Particular Aspects on Applying Nanocarbon Quantum Dots for HIV Inhibition and Theranostics: a Review

2021 ◽  
Vol 43 (3) ◽  
pp. 361-361
Author(s):  
Yaung Kwee Yaung Kwee ◽  
Alfinda Novi Kristanti and Mochamad Zakki Fahmi Alfinda Novi Kristanti and Mochamad Zakki Fahmi
Keyword(s):  
Quantum Dots ◽  
Highly Active Antiretroviral Therapy ◽  
Rna Virus ◽  
Carbon Quantum Dots ◽  
Water Soluble ◽  
High Yield ◽  
Highly Active ◽  
Global Pandemic ◽  
Color Tunable ◽  
Current Utilization

Viral infection is a globally leading health issue, causing significantly unfavourable mortality with an adversely decreasing socio-economic growth. To solve those infections of global pandemic HIV specifically, the current utilization of highly active antiretroviral therapy (HAART) in human deficiency virus (HIV) theranostics has remarkably improved the life’s duration of patients infected by human immunodeficiency virus (HIV); however, the unfortunate drawbacks in combination with prolonged HAART therapy need to be used continuously along patient’s lifetime. Additionally, RNA virus of COVID-19 is also associated with viral pneumonia and acute respiratory distress syndrome causing significant morbidity and mortality. Meanwhile, many scientific researchers have explored the successive novelty of carbon quantum dots (CQDs) as alternative to HIV or other related viruses theranostics in the field of antiviral drugs research, but the attempt has been still challenging to introduce perfect antiviral CQDs with excellent biocompatibility, drug resistance, and safety at several areas in the virus’s life cycle. On the contrary, CQDs-based nano-therapy is currently promising because those carbon quantum dots had multiple favourable properties, including significant antiviral response effects, water-soluble activity, color-tunable fluorescence, high yield, low cytotoxic behaviour, and promising biocompatibility. In this review, some effectively recent progress of promising CQDs forviral inhibition and theranostics explored by many studies are systematically summarized.

A simple one-step hydrothermal route towards water solubilization of carbon quantum dots from soya-nuggets for imaging applications

RSC Advances ◽  
2015 ◽  
Vol 5 (106) ◽  
pp. 87528-87534 ◽  
Author(s):  
Prashant Dubey ◽  
Kumud Malika Tripathi ◽  
Ragini Mishra ◽  
Anshu Bhati ◽  
Anupriya Singh ◽  
...  
Keyword(s):  
Quantum Dots ◽  
Hydrothermal Process ◽  
Carbon Quantum Dots ◽  
Single Step ◽  
Water Soluble ◽  
High Yield ◽  
Synthetic Approach ◽  
Hydrothermal Route ◽  
E Coli ◽  
One Step

A high yield simple synthetic approach for water soluble photoluminescent carbon quantum dots via a single step, hydrothermal process, was described. Photoluminescent multi-colored emissions were used to label E. coli cells.

scholarly journals Green Preparation of Fluorescent Carbon Quantum Dots from Cyanobacteria for Biological Imaging

Polymers ◽  
2019 ◽  
Vol 11 (4) ◽  
pp. 616 ◽  
Author(s):  
Xi Wang ◽  
Pei Yang ◽  
Qian Feng ◽  
Taotao Meng ◽  
Jing Wei ◽  
...  
Keyword(s):  
Quantum Dots ◽  
Carbon Source ◽  
Large Scale ◽  
Low Cost ◽  
Average Diameter ◽  
Carbon Quantum Dots ◽  
Water Soluble ◽  
High Concentration ◽  
Wide Range ◽  
Low Cytotoxicity

Biomass-based carbon quantum dots (CQDs) have become a significant carbon materials by their virtues of being cost-effective, easy to fabricate and low in environmental impact. However, there are few reports regarding using cyanobacteria as a carbon source for the synthesis of fluorescent CQDs. In this study, the low-cost biomass of cyanobacteria was used as the sole carbon source to synthesize water-soluble CQDs by a simple hydrothermal method. The synthesized CQDs were mono-dispersed with an average diameter of 2.48 nm and exhibited excitation-dependent emission performance with a quantum yield of 9.24%. Furthermore, the cyanobacteria-derived CQDs had almost no photobleaching under long-time UV irradiation, and exhibited high photostability in the solutions with a wide range of pH and salinity. Since no chemical reagent was involved in the synthesis of CQDs, the as-prepared CQDs were confirmed to have low cytotoxicity for PC12 cells even at a high concentration. Additionally, the CQDs could be efficiently taken up by cells to illuminate the whole cell and create a clear distinction between cytoplasm and nucleus. The combined advantages of green synthesis, cost-effectiveness and low cytotoxicity make synthesized CQDs a significant carbon source and broaden the application of cyanobacteria and provide an economical route to fabricate CQDs on a large scale.

Preparation of functionalized water-soluble photoluminescent carbon quantum dots from petroleum coke

Carbon ◽  
2014 ◽  
Vol 78 ◽  
pp. 480-489 ◽  
Author(s):  
Mingbo Wu ◽  
Yue Wang ◽  
Wenting Wu ◽  
Chao Hu ◽  
Xiuna Wang ◽  
...  
Keyword(s):  
Quantum Dots ◽  
Petroleum Coke ◽  
Carbon Quantum Dots ◽  
Water Soluble

β-Cyclodextrin functionalized carbon quantum dots as sensors for determination of water-soluble C60 fullerenes in water

The Analyst ◽  
2016 ◽  
Vol 141 (9) ◽  
pp. 2682-2687 ◽  
Author(s):  
Angelina Cayuela ◽  
M. Laura Soriano ◽  
Miguel Valcárcel
Keyword(s):  
Quantum Dots ◽  
Direct Determination ◽  
Carbon Quantum Dots ◽  
Water Soluble ◽  
Soluble C ◽  
Water Soluble C ◽  
C60 Fullerenes

A selective photoluminescence method based on Carbon Quantum Dots (CQDs) functionalized with carboxymethyl-β-cyclodextrin for the direct determination of water-soluble C60 fullerene has been developed.

scholarly journals Facile and High-yield Synthesis of N-doped Carbon Quantum Dots from Biomass Quinoa Saponin for the Detection of Co2+

2021 ◽  
Vol 2021 ◽  
pp. 1-11
Author(s):  
Cuo Zhou ◽  
Shunwei Wu ◽  
Shenghui Qi ◽  
Weijun Song ◽  
Chunyan Sun
Keyword(s):  
Quantum Dots ◽  
Metal Ion ◽  
Light Emission ◽  
Low Cost ◽  
Carbon Quantum Dots ◽  
High Yield ◽  
Excitation Wavelength ◽  
Uniform Size ◽  
Orthogonal Experiments ◽  
Co2 Detection

Hydrothermal synthesis of carbon quantum dots (CQDs) from natural biomass is a green and sustainable route for CQDs applications in various fields. In this work, the preparation and characterization of CQDs based on quinoa saponin were investigated. The optimum synthetic conditions determined by orthogonal experiments were as follows: 2 g quinoa saponin powder and 0.04 mol ethylenediamine reacted at 200°C for 10 h. The relative fluorescence quantum yield (QY = 22.2%) can be obtained, which is higher than some results reported in the literatures. The prepared CQDs had a small and uniform size (∼2.25 nm) and exhibited excitation wavelength-dependent blue light emission behavior. The CQDs displayed excellent sensitivity for Co2+ detection along with good linear correlation ranging from 20 to 150 µM and the detection limit of 0.49 µM. The CQDs prepared in this experiment were successfully implanted into soybean sprouts for fluorescence imaging. The sprouts could grow healthily even soaked in the CQDs solution for two weeks, demonstrating the low toxicity of the CQDs. The advantages of the CQDs, such as low cost, ease of manufacture, nontoxicity, and stability, have potential applications in many areas such as metal ion detection and biosensing.

The selective deprotonation of carbon quantum dots for fluorescent detection of phosphate and visualization of latent fingerprints

Nanoscale ◽  
2021 ◽  
Author(s):  
Li Yang ◽  
Qi Zhang ◽  
Ying Han ◽  
Hongjuan Li ◽  
Shiguo Sun ◽  
...  
Keyword(s):  
Quantum Dots ◽  
Rapid Determination ◽  
Carbon Quantum Dots ◽  
Water Soluble ◽  
Fluorescent Detection ◽  
Latent Fingerprints ◽  
Fluorescent Sensing ◽  
Turn On ◽  
Sensing Platform

We developed a water-soluble, stable and selective “turn-on” fluorescent sensing platform based on carbon quantum dots (CQDs) for rapid determination of the phosphate (Pi) in aqueous solutions and visualization of...

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