scholarly journals High Levels of Energy Expenditure in Shorebirds; Metabolic Adaptations to an Energetically Expensive Way of Life

Ardea ◽  
2002 ◽  
Vol 38-90 ◽  
pp. 175-187 ◽  
Author(s):  
Marcel Kersten ◽  
Theunis Piersma
Obesity ◽  
2020 ◽  
Vol 28 (10) ◽  
pp. 1922-1931 ◽  
Author(s):  
E. Matthew Morris ◽  
Roberto D. Noland ◽  
Julie A. Allen ◽  
Colin S. McCoin ◽  
Qing Xia ◽  
...  

2020 ◽  
Vol 134 (5) ◽  
pp. 473-512 ◽  
Author(s):  
Ryan P. Ceddia ◽  
Sheila Collins

Abstract With the ever-increasing burden of obesity and Type 2 diabetes, it is generally acknowledged that there remains a need for developing new therapeutics. One potential mechanism to combat obesity is to raise energy expenditure via increasing the amount of uncoupled respiration from the mitochondria-rich brown and beige adipocytes. With the recent appreciation of thermogenic adipocytes in humans, much effort is being made to elucidate the signaling pathways that regulate the browning of adipose tissue. In this review, we focus on the ligand–receptor signaling pathways that influence the cyclic nucleotides, cAMP and cGMP, in adipocytes. We chose to focus on G-protein–coupled receptor (GPCR), guanylyl cyclase and phosphodiesterase regulation of adipocytes because they are the targets of a large proportion of all currently available therapeutics. Furthermore, there is a large overlap in their signaling pathways, as signaling events that raise cAMP or cGMP generally increase adipocyte lipolysis and cause changes that are commonly referred to as browning: increasing mitochondrial biogenesis, uncoupling protein 1 (UCP1) expression and respiration.


2019 ◽  
Vol 89 (1-2) ◽  
pp. 80-88 ◽  
Author(s):  
Juliana Soares Severo ◽  
Jennifer Beatriz Silva Morais ◽  
Taynáh Emannuelle Coelho de Freitas ◽  
Ana Letícia Pereira Andrade ◽  
Mayara Monte Feitosa ◽  
...  

Abstract. Thyroid hormones play an important role in body homeostasis by facilitating metabolism of lipids and glucose, regulating metabolic adaptations, responding to changes in energy intake, and controlling thermogenesis. Proper metabolism and action of these hormones requires the participation of various nutrients. Among them is zinc, whose interaction with thyroid hormones is complex. It is known to regulate both the synthesis and mechanism of action of these hormones. In the present review, we aim to shed light on the regulatory effects of zinc on thyroid hormones. Scientific evidence shows that zinc plays a key role in the metabolism of thyroid hormones, specifically by regulating deiodinases enzymes activity, thyrotropin releasing hormone (TRH) and thyroid stimulating hormone (TSH) synthesis, as well as by modulating the structures of essential transcription factors involved in the synthesis of thyroid hormones. Serum concentrations of zinc also appear to influence the levels of serum T3, T4 and TSH. In addition, studies have shown that Zinc transporters (ZnTs) are present in the hypothalamus, pituitary and thyroid, but their functions remain unknown. Therefore, it is important to further investigate the roles of zinc in regulation of thyroid hormones metabolism, and their importance in the treatment of several diseases associated with thyroid gland dysfunction.


1996 ◽  
Vol 41 (8) ◽  
pp. 802-802
Author(s):  
Jean A. Carter
Keyword(s):  

2012 ◽  
Author(s):  
Kathryn L. Norsworthy ◽  
Kelly Caniglia ◽  
Sharri Harmel ◽  
Alexandra Lajeunesse ◽  
April Obermeyer ◽  
...  
Keyword(s):  

1987 ◽  
Author(s):  
P. Christopher Earley ◽  
Pauline Wojnaroski ◽  
William Prest
Keyword(s):  

1990 ◽  
Author(s):  
Logan Wright ◽  
Kurt von Bussmann ◽  
Alice G. Friedman ◽  
Mary Khoury ◽  
Fredette Owens ◽  
...  
Keyword(s):  

Author(s):  
U Elbelt ◽  
V Haas ◽  
T Hofmann ◽  
S Jeran ◽  
H Pietz ◽  
...  

2009 ◽  
pp. 123-129
Author(s):  
Yu. Golubitsky

The article considers business practices of Moscow small industry in the XIX century, basing upon physiological sketches of N. Polevoy and I. Kokorev, statistical data and the classification of professions are also presented. The author claims that the heroes of the analyzed sketches are the forefathers of Moscow small businesses and shows what a deep similarity their occupations and a way of life bear to the present-day routine existence of small enterprises.


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