scholarly journals Cytomorphological Spectrum of Salivary Gland Lesions by Fine Needle Aspiration Cytology

2021 ◽  
Vol 8 (7) ◽  
pp. 397-401
Author(s):  
Mayur Ambekar ◽  
Rachana Binayke

Introduction: Salivary gland lesions encompass a baffling subset of lesions with overlapping morphologies on cytomorphology, due to their heterogenous histologies and rare enough to sometimes bewilder even the most knowledgeable cytopathologists. The technique of fine needle aspiration (FNA) cytology in the evaluation of salivary gland lesion is simple to perform, saves time, reliable, safe and inexpensive. FNA is highly accurate when used in proper clinical setting and supported by appropriate clinical and relevant diagnostic data. Rapidity of obtaining a pathological diagnosis allows more intelligent therapeutic approach. Materials and Methods: It was a prospective study carried out in the cytology section of pathology department for a period of two years using fine needle aspiration as a diagnostic tool as per standard protocol. The clinical and radiological data were obtained from the patient’s case papers and collaboration with the operating surgeon, the lesions were analysed on cytology. Haematoxylin & Eosin, Papanicolaou stain and Giemsa were used as standard stains. Results: A total of 66 cases of salivary gland lesions were aspirated for a period of two years. Majority of cases were in the age group of 21-30 years with 36 male patients (55%) and 30 female patients (45%). About 44(66.7%), 19(28.8%), 1(1.5%) and 2(3.0%) cases occurred in parotid gland, submandibular gland, sublingual gland and minor salivary gland respectively. There were 21(32%) cases of non-neoplastic lesions and 45(68%) cases of neoplastic lesions. Histopathological specimens were available in 11 out of 66 cases and showed correlation with cytological findings. Conclusion: Fine needle aspiration cytology of salivary gland lesions has high diagnostic accuracy, helps in appropriate therapeutic management and is useful as a diagnostic procedure because of the availability of earlier diagnosis in comparison with the histopathology. Keywords: Salivary gland lesions, fine needle aspiration cytology, neoplastic, non-neoplastic.

1970 ◽  
Vol 1 (2) ◽  
pp. 108-113 ◽  
Author(s):  
S Vaidya ◽  
A Sinha ◽  
S Narayan ◽  
S Adhikari ◽  
KC Sabira

Background: A wide variety of benign and malignant tumours originate in the salivary glands and insufficient tumour cells make their diagnosis difficult in some patients. The aim of this study was to evaluate the efficacy of fine-needle aspiration cytology in the diagnosis of salivary gland lesions and to correlate cytological findings with histopathology. Materials and Methods: This was a prospective study done from September 2002 to May 2004. Fine needle aspiration cytology was performed in 58 patients with clinically significant salivary gland masses. Results: Fine needle aspiration cytology categorized 67.24% of the salivary gland lesions as neoplastic and 32.76% as non-neoplastic lesions. Amongst the neoplastic lesions, 76.9% were benign and 23.1% were malignant cases. Histopathological examination revealed that 81.05% of the cases were benign and 18.95% were malignant. Fine needle aspiration cytology had a sensitivity, specificity and diagnostic accuracy of 81.82%, 100% and 96.55%, respectively. The positive predictive value and negative predictive value was 100% and 95.9%, respectively. Conclusion: Fine needle aspiration of the salivary gland is a safe and reliable technique in the primary diagnosis of salivary gland lesions. Although, limitations are encountered while predicting specific lesions on cytology, especially when dealing with cystic and some malignant lesions, this study has shown that fine needle aspiration cytology has a high sensitivity, specificity and diagnostic accuracy in diagnosing salivary gland lesions. Keywords: Salivary glands; Fine needle aspiration cytology; Histopathology DOI: http://dx.doi.org/10.3126/jpn.v1i2.5403 JPN 2011; 1(2): 108-113


2017 ◽  
Vol 4 (2) ◽  
pp. 307
Author(s):  
Anil R. Joshi ◽  
Dnyaneshwar S. Jadhav ◽  
Balaji D. Baste ◽  
Shweta K. Ranka

Background: Fine needle aspiration cytology (FNAC) of suspected salivary gland lesions has an established role in preoperative diagnosis and management of patients. However diverse morphological patterns and overlapping features make it a challenging job, to give a precise diagnosis at times.Methods: This was a prospective study done from October 2011 to October 2013. Fine needle aspiration cytology was performed in 64 patients with clinically significant salivary gland lesions.Results: Fine needle aspiration cytology categorized 38 (59.4%) of the salivary gland lesions as neoplastic and 26 (40.6 %) as non- neoplastic lesions. Amongst the neoplastic lesions, 86.9% were benign and 13.2% were malignant cases.Conclusions: FNAC of the salivary gland is simple, cheap, safe and reliable technique in the primary diagnosis of salivary gland lesions.


Cytopathology ◽  
2019 ◽  
Vol 30 (6) ◽  
pp. 662-666
Author(s):  
Aanchal Kakkar ◽  
Nishu Bhardwaj ◽  
Pirabu Sakthivel ◽  
Chirom Amit Singh ◽  
Deepali Jain ◽  
...  

2021 ◽  
Vol 8 (14) ◽  
pp. 893-898
Author(s):  
Pradip Ramabhau Butale ◽  
Sagar Jagdish Gawai

BACKGROUND Fine needle aspiration cytology (FNAC) is a method for the diagnosis of superficial lesions like swellings of the salivary glands since many years. The present study was undertaken to identify the patterns of salivary gland lesions (SGL) on FNAC and histopathology specimens and also describe the age and sex distribution of SGL. METHODS A total 319 cases of SGL were studied from June 2009 to July 2019 which included both retrospective and prospective cases. A detailed history was taken, clinical and necessary laboratory investigations were done; and then FNAC of salivary gland was done. Histopathology examination of specimens was done whenever available; FNAC and histopathology slides of retrospective cases were reviewed. Correlation between cytomorphology and histomorphology was done only where available. RESULTS The majority of cases was in the age group of 21 - 40 years (42.98 %) with female predominance (53 %) and commonest gland involved was parotid gland (52.97 %) in both the sexes. 138 (43 %) cases were non-neoplastic lesions and 181 (57 %) were diagnosed as neoplastic lesions. Of the 138 non neoplastic lesions, on cytology and histopathology, sialadenitis constituted 110 (79.71 %) cases; most being chronic sialadenitis (107). Out of 181 neoplastic lesions, 142 (77.78 %) were benign while 39 (22.22 %) cases were malignant. Pleomorphic adenoma was the commonest benign neoplasm (71.27 %) and mucoepidermoid carcinoma (66.69 %) was the commonest malignant neoplasm. Histopathological correlation was available in 37 cases. CONCLUSIONS FNAC is useful as an outdoor diagnostic procedure because of the availability of earlier diagnosis in comparison with the histopathological diagnosis. Histopathology correlation is helpful in cases where diagnosis at FNAC is difficult. KEYWORDS FNAC, Salivary Glands, Histopathology, Specimens, Cytomorphology, Sialadenitis, Pleomorphic Adenoma, Mucoepidermoid Carcinoma


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