scholarly journals Adherence to Antihypertensive Medications and Its Determinants in Hypertensive Patients - A Complete Review

2021 ◽  
Vol 8 (2) ◽  
pp. 42-48
Author(s):  
Satish S ◽  
Manju Jose ◽  
A R Shabaraya

Hypertension is a global health problem, it causes complications of cardiovascular diseases, stroke, and renal failure leading to early mortality and disability. Adherence to antihypertensive medications helps to control blood pressure levels. WHO defines adherence as ''the extent to which a person's behavior taking medication, following a diet, and / or executing lifestyle changes-corresponds with agreed recommendations from a health care provider. Poor adherence is the major cause of uncontrolled BP. Common barriers to adherence are under the patient's control, so that attention to them is a necessary and important step in improving adherence. The factors driving patients’ adherence to medication are multifactorial, but can be grouped under five main domains including socioeconomic factors, healthcare system related factors, disease related factors, therapy-related factors and patient-related factors. Identifying factors that affect medication adherence is the first step towards improving adherence. This article covers various factors influencing medication non adherence among hypertensive patients. Keywords: Hypertension, medication adherence.

2020 ◽  
Vol 26 (1) ◽  
Author(s):  
Fahad M. Algabbani ◽  
Aljoharah M. Algabbani

Abstract Background Hypertension is a major risk factor for cardiovascular disease, which is the leading cause of mortality globally. Patient’s adherence to treatment is a cornerstone factor in controlling hypertension and its complications. This study assesses hypertension patients’ adherence to treatment and its associated factors. Methods This cross-sectional study conducted in Riyadh, Saudi Arabia. The study targeted outpatients aged ≥18 years who were diagnosed with hypertension. Participants were recruited using a systemic sampling technique. The two main measurements were assessing adherence rate of antihypertensive medications using Morisky scale and identifying predictors of poor medication adherence among hypertensive patients including socio-economic and demographic data, health status, clinic visits, medication side effects, medications availability, and knowledge. Descriptive and logistic regression analyses were performed to assess factors associated with poor adherence. Results A total of 306 hypertensive outpatients participated in this study. 42.2% of participants were adherent to antihypertensive medications. Almost half of participants (49%) who reported having no comorbidities were adherent to antihypertensive medications compared to participants with one or more than one comorbidities 41, 39% respectively. The presence of comorbid conditions and being on multiple medications were significantly associated with medication adherence (P-values, respectively, < 0.004, < 0.009). Patients with good knowledge about the disease and its complications were seven times more likely to have good adherence to medication (P <  0.001). Conclusions Non-adherence to medications is prevalent among a proportion of hypertensive patients which urges continuous monitoring to medication adherence with special attention to at risks groups of patients. Patients with comorbidities and on multiple medications were at high risk of medication non-adherence. Patients’ knowledge on the disease was one of the main associated factors with non-adherence.


2021 ◽  
Vol 8 (7) ◽  
pp. 30-35
Author(s):  
Satish S ◽  
Minnu Sara Sam ◽  
A R Shabaraya

Prevalence of hypertension is increasing exponentially in India. Hence hypertension has become a crucial public health problem in India. High blood pressure (BP) could be a major risk factor for cardio vascular disease and better control can result in prevention of 300,000 of the 1.5 million annual deaths from cardiovascular diseases in India. Various studies among Indian patients evident that not adherence to their antihypertensive regimen and this might end in poor blood pressure control. Adherence to medication among the hypertensive people from the current studies is poor. A comprehensive strategy to enhance adherence to antihypertensive medications is the need of the hour. In this article an attempt has been made to compile all the research evidence on prevalence of Medication Adherence among hypertensive patients in India. Keywords: Medication, Adherence, Prevalence, Hypertension, India.


Nutrients ◽  
2020 ◽  
Vol 12 (6) ◽  
pp. 1548 ◽  
Author(s):  
Marika Massaro ◽  
Egeria Scoditti ◽  
Maria Annunziata Carluccio ◽  
Nadia Calabriso ◽  
Giuseppe Santarpino ◽  
...  

The increasing access to antihypertensive medications has improved longevity and quality of life in hypertensive patients. Nevertheless, hypertension still remains a major risk factor for stroke and myocardial infarction, suggesting the need to implement management of pre- and hypertensive patients. In addition to antihypertensive medications, lifestyle changes, including healthier dietary patterns, such as the Dietary Approaches to Stop Hypertension (DASH) and the Mediterranean diet, have been shown to favorably affect blood pressure and are now recommended as integrative tools in hypertension management. An analysis of the effects of nutritional components of the Mediterranean diet(s) on blood pressure has therefore become mandatory. After a literature review of the impact of Mediterranean diet(s) on cardiovascular risk factors, we here analyze the effects of olive oil and its major components on blood pressure in healthy and cardiovascular disease individuals and examine underlying mechanisms of action. Both experimental and human studies agree in showing anti-hypertensive effects of olive oil. We conclude that due to its high oleic acid and antioxidant polyphenol content, the consumption of olive oil may be advised as the optimal fat choice in the management protocols for hypertension in both healthy and cardiovascular disease patients.


2020 ◽  
Vol 30 (1) ◽  
Author(s):  
Ebrahim Aliafsari Mamaghani ◽  
Edris Hasanpoor ◽  
Esmaiel Maghsoodi ◽  
Farzaneh Soleimani

BACKGROUND: Poor adherence to medication regimen leads to poor health outcomes, increased medical costs and increased death rate due to hypertension. The aim of this study was to evaluate baseline barriers to medication adherence among hypertensive patients in deprived rural areas.METHODS: A cross-sectional study was conducted on 238 hypertensive patients living in deprived rural areas of Iran. Data were collected using a questionnaire consisting of demographic information, Morisky medication adherence scale and the barriers to medication adherence that were reliable and valid.RESULTS: The results of the study showed that medication adherence was significantly decreased and had a significant positive correlation with gender and economic status, while it had a negative correlation with age. Medication Adherence had a positive correlation with the duration of hypertension, while it had a negative correlation with the number of medications used and concurrently with other diseases.CONCLUSIONS: Based on the present study it can be concluded that enhanced knowledge about illness and treatment in rural communities is improves the medical adherence. Financial supports along with the reduced number of prescribed drugs are also found to be the determining factors in the medical adherence. 


2021 ◽  
Vol 18 (5) ◽  
pp. 1123-1132
Author(s):  
Muhammad Amer ◽  
Nisar-Ur-Rahman ◽  
Saeed-Ur-Rashid Nazir ◽  
Atif Raza ◽  
Humayun Riaz ◽  
...  

Purpose: To determine knowledge regarding hypertension, adherence to medication and HealthRelated Quality of Life (HRQoL), and their associations in hypertensive patients in Pakistan. Methods: A cross-sectional study was conducted among 384 hypertensive patients attending a tertiary health care public sector hospital in Islamabad, Pakistan. Data were collected using knowledge questionnaire regarding hypertension, Morisky Medication Adherence Scale, and EuroQol (EQ-5D) scale. Results: The mean systolic and diastolic blood pressures of the 384 patients were 140.39 ± 15.485 and 88.74 ± 10.683 mmHg, respectively. The coefficient of correlation between knowledge regarding hypertension and adherence was 0.638 (p < 0.001), showing a positive association. The correlation coefficient between knowledge and HRQoL was 0.709 (p < 0.001), suggesting a good association. The correlation coefficient between adherence to medication and HRQoL was 0.545 (p < 0.001), which indicated a positive correlation. Conclusion: These results indicate that there are statistically significant associations between hypertension knowledge and HRQoL, hypertension knowledge and medication adherence, and between adherence and HRQoL in the hypertensive patients studied.


2020 ◽  
Vol 33 (11) ◽  
pp. 1038-1046 ◽  
Author(s):  
Wenjuan Gao ◽  
Hong Liu ◽  
Caiying Ge ◽  
Xinying Liu ◽  
Hongyan Jia ◽  
...  

Abstract BACKGROUND Hypertension remains a global health problem. Since, there is a significant positive correlation between antihypertensive medication adherence and blood pressure control, it is therefore of great importance to elucidate the determinants of adherence to antihypertensive medications among hypertensive patients. METHODS Hereby, we retrospectively analyzed the medical records of a hypertensive cohort recruited from a community hospital in Beijing, China, to investigate the factors affecting adherence to antihypertensive medications using decision trees. In addition, all data were assigned into a training set (75%) and testing set (25%) by the random number seed method to build and validate a compliance predictive model. We identified that how many times patients became nonadherent to antihypertensive medications in the year before the first prescription, types of antihypertensive drugs used in the year before the first prescription, body weight, smoking history, total number of hospital visits in the past year, total number of days of medication use in the year before enrollment, age, total number of outpatient follow-ups in the year after the first prescription, and concurrent diabetes greatly affected the compliance to antihypertensive medications. RESULTS The compliance predictive model we built showed a 0.78 sensitivity and 0.69 specificity for the prediction of the compliance to antihypertensive medications, with an area under the representative operating characteristics curve of 0.810. CONCLUSIONS Our data provide new insights into the improvements of the compliance to antihypertensive medications, which is beneficial for the management of hypertension, and the compliance predictive model may be used in community-based hypertension management.


2019 ◽  
Vol 34 (Supplement_2) ◽  
pp. ii36-ii44 ◽  
Author(s):  
Matthew Hing ◽  
Risa M Hoffman ◽  
Juliet Seleman ◽  
Florence Chibwana ◽  
Daniel Kahn ◽  
...  

Abstract Non-communicable diseases like hypertension are increasingly common among individuals living with HIV in low-resource settings. The prevalence of hypertension among people with HIV in Malawi, e.g. has been estimated to be as high as 46%. However, few qualitative studies have explored the patient experience with comorbid chronic disease. Our study aimed to address this gap by using the health belief model (HBM) to examine how comparative perceptions of illness and treatment among participants with both HIV and hypertension may affect medication adherence behaviours. We conducted semi-structured interviews with 75 adults with HIV and hypertension at an urban clinic in Lilongwe, Malawi. Questions addressed participants’ experiences with antiretroviral and antihypertensive medications, as well as their perspectives on HIV and hypertension as illnesses. Interviews were performed in Chichewa, transcribed, translated into English and analysed using ATLAS.ti. Deductive codes were drawn from the HBM and interview guide, with inductive codes added as they emerged from the data. Self-reported medication adherence was much poorer for hypertension than HIV, but participants saw hypertension as a disease at least as concerning as HIV—primarily due to the perceived severity of hypertension’s consequences and participants’ limited ability to anticipate them compared with HIV. Differences in medication adherence were attributed to the high costs of antihypertensive medications relative to the free availability of antiretroviral therapy, with other factors like lifestyle changes and self-efficacy also influencing adherence practices. These findings demonstrate how participants draw on past experiences with HIV to make sense of hypertension in the present, and suggest that although patients are motivated to control their hypertension, they face individual- and system-level obstacles in adhering to treatment. Thus, health policies and systems seeking to provide integrated care for HIV and hypertension should be attentive to the complex illness experiences of individuals living with these diseases.


2016 ◽  
Vol 2016 ◽  
pp. 1-7 ◽  
Author(s):  
Azin Behnood-Rod ◽  
Omid Rabbanifar ◽  
Pirouz Pourzargar ◽  
Alireza Rai ◽  
Zahra Saadat ◽  
...  

Introduction. Appropriate adherence to medication is still a challenging issue for hypertensive patients. We determined adherence to antihypertensive(s) and its associated factors among 280 Iranian patients.Methods. They were recruited consecutively from private and university health centers and pharmacies in four cities. The validated Persian version of the 8-item Morisky Medication Adherence Scale (MMAS-8) was administered to measure adherence.Results. Mean (±SD) overall MMAS-8 score was 5.75 (±1.88). About half of the sample (139 cases, 49.6%) showed low adherence (MMAS-8 score < 6). There was a negative linear association between the MMAS-8 score and systolic BP (r=-0.231,P<0.001) as well as diastolic BP (r=-0.280,P<0.001). In linear regression model, overweight/obesity (B=-0.52,P=0.02), previous history of admission to emergency services due to hypertensive crisis (B=-0.79,P=0.001), and getting medication directly from drugstore without refill prescription in hand (B=-0.51,P=0.04) were factors recognized to have statistically significant association with the MMAS-8 score.Conclusion. Antihypertensive adherence was unsatisfactory. We suggest that health care providers pay special attention and make use of the aforementioned findings in their routine visits of hypertensive patients to recognize those who are vulnerable to poor adherence.


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