scholarly journals A case of the third interdigit squamous cell carcinoma reconstructed by the first web space flap.

Skin Cancer ◽  
1993 ◽  
Vol 8 (1) ◽  
pp. 84-87
Author(s):  
Hiroshi SHIRAI ◽  
Hiko HYAKUSOKU ◽  
Masatoshi FUMIIRI ◽  
Mikako AOKI ◽  
Mitsuyoshi HONDA
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
The Third ◽  
Web Space

Invasive Squamous Cell Carcinoma with Osteomyelitis of the Foot

2015 ◽  
Vol 105 (4) ◽  
pp. 374-376
Author(s):  
Morteza Khaladj ◽  
Rose-Mary Mbibong ◽  
Nisha Shah ◽  
Ayesha Mohiuddin ◽  
Aqsa Siddiqui
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Chronic Wounds ◽  
Squamous Cell Carcinomas ◽  
Initial Presentation ◽  
Invasive Squamous Cell Carcinoma ◽  
The Sun ◽  
The Third

Squamous cell carcinomas are often seen on the sun-exposed areas of the skin and are rarely observed on the digits of the foot. However, there have been incidences of squamous cell carcinoma developing in the presence of chronic wounds with osteomyelitis, thus complicating the treatment. We present a patient with osteomyelitis who developed invasive squamous cell carcinoma of the third digit. We conclude that wounds with osteomyelitis may have underlying pathologic abnormalities that are not obvious on initial presentation.

scholarly journals Squamous Cell Carcinoma in the Third Eyelid of a Dog

2021 ◽  
Vol 49 ◽  
Author(s):  
Beatriz Crepaldi Aléssio ◽  
Juliana Paniago Lordello de Paula ◽  
Gustavo Gomes de Oliveira ◽  
Silvana Marques Caramalac ◽  
Alda Izabel de Souza ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Fine Needle Aspiration ◽  
Fine Needle Aspiration Cytology ◽  
Needle Aspiration ◽  
Aspiration Cytology ◽  
Fine Needle ◽  
The Third ◽  
Needle Aspiration Cytology

Background: Squamous cell carcinoma is a malignant neoplasm that originates from the keratinized stratified squamous epithelium and predominantly affect light-skinned animals. In dogs, breeds such as American Staffordshire Terriers, white or speckled Bull Terriers, and Beagles have a higher predisposition. Squamous cell carcinoma presents in the skin, at slightly pigmented or hairy sites, especially in digits, but also may occur in the nasal planum, oral mucosa, and rarely, in the eye. Considering that few reports have been published on eye neoplasms, the aim of this paper is to describe a dog with a lesion in the third eyelid of his right eye which was diagnosticated with squamous cell carcinoma. Case: A 10-year-old male American Staffordshire dog was admitted to the Veterinary Medical Teaching Hospital of the Veterinary Medicine and Zootechnics College, Universidade Federal de Mato Grosso do Sul (UFMS), Campo Grande, Brazil with injury to the right eye. During the physical examination, there was also a non-adhered lump near the foreskin, measuring 1.5 cm in diameter. In addition, there was another lump in the third eyelid of the right eye, approximately 3 mm in diameter. Cytology of the dermal nodule was performed by fine-needle aspiration cytology; however, the sample was insufficient for cytological evaluation. Therefore, the animal was placed under general anesthesia for skin lump excision and for fine-needle aspiration cytology of the third eyelid nodule. The histopathological exam revealed high cellularity of epithelial cells, intense anisocytosis and pleomorphism, cytoplasmic basophilia and vacuolation, multiple evident nucleoli, and anisocariosis and coarse chromatin. These finds were compatible with squamous cell carcinoma, which was the same result suggested by fine-needle aspiration cytology of the third eyelid sample. Based on these results, the dog underwent a surgical procedure for enucleation and subsequent histopathological evaluation of the nodule in the third eyelid, which confirmed the squamous cell carcinoma diagnosis.Discussion: Squamous cell carcinoma is an extremely aggressive tumor with low metastatic potential, characterized by invasion of the dermis by proliferation of malignant epithelial cells from the prickly layer. It is most common in elderly animals, and American Staffordshires are among the breeds that are predisposed to develop this tumor. The clinical presentation is highly variable, depending on the tissue involved. In this case, the dermal nodule was an elevated area on the skin and the third eyelid nodule resembled an ulcerative mass. Cytological examination from the lesion located on the third eyelid, showed malignancies cytoplasmic changes frequently found in carcinomas such as anisocytosis, cytoplasmic basophilia, and cell pleomorphism. In addition, nuclear changes had also occurred, such as crass chromatin, multiple evident nucleoli, and multinucleated cells. A presumptive diagnosis was made based on cytology and was confirmed after biopsy and histopathological examination. Because it is uncommon in dogs, squamous cell carcinoma of the third eyelid may be misdiagnosed, delaying correct treatment, and accelerating the development of the tumor. Currently, various therapeutic approaches are available, such as surgical excision, electrosurgery, cryosurgery, radiation, and hyperthermia. The choice of treatment depends on the location and stage of the lesions. Surgical treatment should be aimed at removing sufficient tissue to leave surgical margins free of neoplastic cells.

scholarly journals Adenosquamous Carcinoma of the Colon

2018 ◽  
Vol 11 (3) ◽  
pp. 791-796 ◽  
Author(s):  
Tagore Sunkara ◽  
Megan E Caughey ◽  
Priyanka Makkar ◽  
Febin John ◽  
Vinaya Gaduputi
Keyword(s):  
Colorectal Cancer ◽  
Colon Cancer ◽  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Adenosquamous Carcinoma ◽  
Colorectal Cancers ◽  
Men And Women ◽  
Carcinoma Of The Colon ◽  
The Third

Overall, colorectal cancer is the third most commonly diagnosed cancer in both men and women, meaning that it is one of the more widely recognized preventable cancers. Instances of colorectal malignancies though are overwhelmingly attributable to adenocarcinoma. Colorectal cancers with components of squamous cell carcinoma represent a statistical anomaly. Here, we present the case of a 50-year-old male, who complained of abdominal pain and weight loss over a 3-month period of time. Biopsies from a colonoscopy ultimately revealed that this patient’s colon cancer consisted of both adenocarcinoma and squamous cell carcinoma, representing a truly exceptional pathology finding in a patient diagnosed with a colorectal cancer.

scholarly journals EXPERIMENTS ON THE CAUSE OF THE RABBIT CARCINOMAS DERIVED FROM VIRUS-INDUCED PAPILLOMAS

1952 ◽  
Vol 95 (3) ◽  
pp. 299-318 ◽  
Author(s):  
William E. Smith ◽  
John G. Kidd ◽  
Peyton Rous
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Recoverable Strain ◽  
The Third ◽  
Negative Results ◽  
Causative Agents ◽  
Morphological Sign ◽  
Favorable Conditions ◽  
Newborn Animals

Three out of four carcinomas arising from rims-induced, rabbit papillomas have grown well after transplantation to sucklings. Two were propagated serially, and it seems likely that all could have been maintained indefinitely had litters been available of newborn animals of the sort in which they arose. These successes are the more worthy of note because of the well-nigh uniform failure of similar growths on transfer to adults. The tumors enlarged with great rapidity in the sucklings, were extraordinarily destructive, and two of them metastaslzed within a few weeks. Many efforts were made to extract causative agents from the three carcinomas, on the assumption that these might be due to variants of the Shope virus. Highly favorable conditions for the demonstration of this latter were provided in the tests; yet their outcome was wholly negative although all of the cancers derived from papillomas caused by "recoverable" strains of virus, and although one of them appeared to be consequent upon only the slightest of alterations toward malignancy on the part of the papilloma from which it came. Extracts of another of the cancers, an anaplastic, squamous-cell carcinoma devoid of any morphological sign of the influence of the Shope virus, yielded typical virus papillomas on several occasions. The wholly negative results with the third cancer must be considered in the light of the fact that the "recoverable" strain of virus causing the papilloma from which it originated could no longer be recovered from such growths on collateral test.

scholarly journals Synchronous Malignant Otitis Externa and Squamous Cell Carcinoma of the External Auditory Canal

2013 ◽  
Vol 2013 ◽  
pp. 1-4
Author(s):  
R. Y. Chin ◽  
T. B. V. Nguyen
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
External Auditory Canal ◽  
Otitis Externa ◽  
Concomitant Treatment ◽  
The Third ◽  
Intravenous Antibiotics ◽  
Malignant Otitis Externa ◽  
Synchronous Tumour

Objectives. To discuss the management of a squamous cell carcinoma in the presence of malignant otitis externa.Study Design. We present only the third reported case in the literature of a synchronous tumour with malignant otitis externa in the literature.Methods. A case report and review of malignant otitis externa and squamous cell carcinomas of the external auditory canal are discussed.Results. A 66-year-old female is presented here with a 2-month history of a painful, discharging left ear refractory to standard antibiotic therapy. Computerised tomography, magnetic resonance imaging, technetium 99 m, and gallium citrate Ga67 scans were consistent with malignant otitis externa. Biopsy in the operating theatre revealed a synchronous squamous cell carcinoma of the external auditory canal. Primary resection of the tumour and surrounding tissues was performed with concomitant treatment with intravenous antibiotics.Conclusions. This is only the third case to be reported in the literature and highlights several important diagnostic and management issues of these two rare conditions. Both conditions may present in a similar manner on clinical assessment and radiological investigations. Aggressive management with surgical resection and treatment with appropriate intravenous antibiotics is necessary to give the best chance for cure.

scholarly journals Frequency and Evolution of Acute Oral Complications in Patients Undergoing Radiochemotherapy Treatment for Head and Neck Squamous Cell Carcinoma

2019 ◽  
pp. 014556131987924 ◽  
Author(s):  
Michelle Palmieri ◽  
Dmitry J. S. Sarmento ◽  
André P. Falcão ◽  
Victor A. O. Martins ◽  
Thais B. Brandão ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Head And Neck ◽  
Squamous Cell ◽  
Oral Mucositis ◽  
Neck Region ◽  
World Health ◽  
Head And Neck Region ◽  
The Third ◽  
Oral Complications

Despite its effectiveness, radiochemotherapy treatment in the head and neck region is accompanied by acute oral complications such as oral mucositis, dysphagia, xerostomia, and dysgeusia. The aim of this study was to analyze and prospectively assess the frequency and evolution of acute oral complications during radiochemotherapy in patients diagnosed with squamous cell carcinoma in the head and neck region. We have analyzed oral complications of 20 patients during 6 weeks of radiochemotherapy treatment for squamous cell carcinoma. Oral mucositis was evaluated according to the World Health Organization criteria, dysphagia, and dysgeusia according to the National Cancer Institute Common Toxicity Criteria, and xerostomia according to parameters set by the Seminars in Radiation Oncology. Mucositis was first observed in the second week and all patients presented some degree of mucositis in the fourth week of radiotherapy. Xerostomia and dysphagia were initially reported already in the first week of radiotherapy. All patients presented xerostomia in the fourth week; however, dysphagia was observed in all patients, only in the sixth week. Dysgeusia was first observed in the second week, becoming more severe in the third week. Acute oral complications can be observed throughout the treatment, but the third week of radiotherapy seems to represent a critical week, regardless of the grade of the complication. The sixth week presents the worst grades of these complications. Knowledge about the natural course of oral complications during radiotherapy is important to develop better strategies for treatment and improve the patients’ quality of life.

scholarly journals Primary Carcinosarcoma of the Helix of the Ear

2005 ◽  
Vol 84 (11) ◽  
pp. 712-715 ◽  
Author(s):  
Vladimir Vincek ◽  
Marjan Mirzabeigi ◽  
Brian S. Jewett ◽  
W. Jarrard Goodwin
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Malignant Fibrous Histiocytoma ◽  
Squamous Cell ◽  
Basal Cell ◽  
Rare Case ◽  
Fibrous Histiocytoma ◽  
Negative Reaction ◽  
The Third ◽  
Immunohistochemical Reaction

We report our histologic and immunohistochemical findings in a rare case of cutaneous carcinosarcoma involving the helix of the ear. The tumor exhibited cellular features of both basal cell and squamous cell carcinoma and a malignant mesenchymal component that was consistent with malignant fibrous histiocytoma. The epithelial component exhibited a positive immunohistochemical reaction to cytokeratin and a negative reaction to vimentin, whereas the mesenchymal component showed a positive immunohistochemical reaction to vimentin and a negative reaction to cytokeratin. To the best of our knowledge, this is only the third reported case of a carcinosarcoma of the ear and the second case in which it developed on the helix.

scholarly journals Tracheal Squamous Cell Carcinoma Treated with Tracheal Resection and Anastomosis in a Cat

2020 ◽  
Vol 2020 ◽  
pp. 1-8
Author(s):  
Zachary A. Miller ◽  
Sheldon Padgett ◽  
Alex Terreros ◽  
Emily Pearce
Keyword(s):  
Squamous Cell Carcinoma ◽  
Radiation Therapy ◽  
Postoperative Complications ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Intraoperative Complications ◽  
Tracheal Resection ◽  
First Report ◽  
The Third ◽  
Resection And Anastomosis

A 10-year-old male castrated domestic shorthair cat presented for a suspected tracheal mass. Radiographs confirmed an intraluminal tracheal mass. Tracheal resection and anastomosis of 5 tracheal rings was performed with minimal, mild intraoperative complications and no postoperative complications. Histopathology of the tracheal mass revealed a diagnosis of squamous cell carcinoma (SCC) with incomplete margins both cranially and caudally. Further treatment, including surgical revision, radiation therapy, or chemotherapy, was recommended. At the time of publication, no further treatment has been initiated, and a scheduled consultation with the oncologist has been canceled. The cat is doing well at home with no reported signs of recurrence 120 days postoperatively. This is the first report of a cat with a tracheal SCC to be treated with a tracheal resection and anastomosis and only the third feline tracheal SCC to be treated in the veterinary literature.

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