Determinants of Gestational Diabetes Mellitus at Tertiary Care Hospital of Lahore

2020 ◽  
pp. 34-38
Author(s):  
OJS Admin
Keyword(s):  
Diabetes Mellitus ◽  
Gestational Diabetes ◽  
Gestational Diabetes Mellitus ◽  
Glucose Intolerance ◽  
Dietary Habits ◽  
Tertiary Care Hospital ◽  
Economic Status ◽  
Tertiary Care ◽  
Care Hospital ◽  
Socio Economic Status

Gestational Diabetes Mellitus (GDM) is defined as glucose intolerance of varying degree with onset or first recognition during pregnancy. Prevalence of GDM is known to vary widely depending on the region of the country, dietary habits, and socio-economic status.

scholarly journals Prevalence of gestational diabetes mellitus and its relationship with various risk factors in a tertiary care hospital in West Bengal with special reference to tribal population, India

2019 ◽  
Vol 7 (4) ◽  
pp. 1098
Author(s):  
Narenrda Kumar Sharma ◽  
Subodh Kumar Mahto ◽  
Rahul Sharma ◽  
Ankita Sheoran ◽  
Sumit Kumar Suman ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Risk Factors ◽  
Risk Factor ◽  
Gestational Diabetes ◽  
Gestational Diabetes Mellitus ◽  
West Bengal ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Care Hospital ◽  
Tribal Population

Background: Gestational diabetes mellitus (GDM) is the most common medical complication and metabolic disorder of pregnancy. The aim and objective of this study was to determine the prevalence of GDM and its relationship with various risk factors with special reference to tribal population.Methods: The study was done in 200 patients between 24 and 28 weeks of gestation, attending antenatal outdoor in a tertiary care hospital of West Bengal.  These patients were given 75gm oral glucose irrespective of the last meal and their plasma glucose was estimated at 2hours. Patients with plasma glucose values ≥140 mg/dl were labelled as GDM. Patients who were diabetic before pregnancy or whose pre pregnancy body mass index was not known or was in labour or had chronic disease, were not included in the study.Results: Prevalence of GDM was 11% in whole population while it was 14.63% and 10.06% in tribal and non-tribal population respectively.  Prevalence of GDM and its correlation with most of risk factors in previous pregnancies was found to be significant in both non-tribal and tribal population. Family history of diabetes mellitus was the most prevalent risk factor in both non-tribal (9.4%) and tribal population (14.63%). There was no single most common risk factor among GDM patients found as there were multiple risk factors present with same frequency in both tribal and non-tribal population.Conclusions: The prevalence of GDM is 14.63% in the tribal population and 10.06% in non-tribal population which is not statically significant (P<0.407). The relation between the prevalence of GDM and risk factors was found to be significant for most of the risk factors.

scholarly journals Maternal and perinatal outcome in gestational diabetes mellitus in a Tertiary Care Hospital in Delhi

2018 ◽  
Vol 22 (1) ◽  
pp. 116 ◽  
Author(s):  
Venus Dalal ◽  
Rajesh Kumari ◽  
Garima Kachhawa ◽  
Ipshita Sahoo ◽  
Rajesh Khadgawat ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Gestational Diabetes ◽  
Gestational Diabetes Mellitus ◽  
Perinatal Outcome ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Care Hospital

Awareness about Gestational Diabetes Mellitus among Antenatal Women Attending tertiary Care Hospital

2012 ◽  
Vol 2 (10) ◽  
pp. 1-3
Author(s):  
Dr. B. Mahalakshmi Dr. B. Mahalakshmi ◽  
◽  
Dr. A. Meriton Stanly ◽  
Dr. Vanishree Dr. Vanishree
Keyword(s):  
Diabetes Mellitus ◽  
Gestational Diabetes ◽  
Gestational Diabetes Mellitus ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Care Hospital

Gestational Diabetes Mellitus in a Tertiary Care Hospital of Kolkata, India: Prevalence, Pathogenesis and Potential Disease Biomarkers

2018 ◽  
Vol 128 (04) ◽  
pp. 216-223
Author(s):  
Jayita Basu ◽  
Chhanda Datta ◽  
Subhankar Chowdhury ◽  
Debasmita Mandal ◽  
Nandan Kumar Mondal ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Risk Factors ◽  
Dna Damage ◽  
Gestational Diabetes ◽  
Gestational Diabetes Mellitus ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Care Hospital ◽  
Disease Pathogenesis ◽  
Disease Biomarkers

Abstract Aims Prevalence of gestational diabetes mellitus (GDM) may vary across a country like India. Risk factors and disease-pathogenesis were also not fully elucidated. This study aimed to examine prevalence of GDM among pregnant women visiting antenatal clinic of a tertiary-care hospital of Kolkata, India; possible mechanism of disease pathogenesis and potency of associated parameters as disease biomarkers were also explored. Methods 735 pregnant women were screened for GDM according to DIPSI (Diabetes in Pregnancy Study Group India) guideline and risk-factors were analyzed. Case-control study was conducted with 114 GDM and 114 matched non-GDM control. Blood sample was collected before glucose load for complete blood count, measurement of reactive oxygen species (ROS) and assessment of DNA damage. Results Prevalence of GDM was found to be 17.2%(127/735). Maternal age, diabetic family history and acanthosis nigricans seemed to be important risk factors. Total ROS, lymphocyte DNA damage (measured by comet-assay) and some inflammatory hematological parameters were significantly higher in GDM compared to control. ROS, comet-tail DNA%, WBC, neutrophil-lymphocyte ratio (NLR) and mean platelet volume (MPV) were established as independent determinants of disease condition after adjustment for pre-gestational body mass index. In receiver operating characteristic analysis, ROS>155.7 arbitrary fluorescent unit, NLR>2.12 and MPV>11.05 fL showed 82.5 & 98.2%, 71.9 & 84.2% and 71.9 & 82.5% sensitivity & specificity respectively in disease prediction. Conclusions Prevalence of GDM seemed to be high in Kolkata on Indian scenario. Oxidative-stress, related DNA-damage and inflammation seemed to have important contribution in pathogenesis of GDM independent of obesity. ROS, NLR and MPV with respective cut-off scores might be used as diagnostic and prognostic biomarkers for better management of the disease.

scholarly journals Prevalence of thyroid dysfunction and autoimmunity among pregnant women with gestational diabetes mellitus in a tertiary care hospital, Visakhapatnam

2020 ◽  
Vol 9 (11) ◽  
pp. 4621
Author(s):  
Srividya Nemani ◽  
Vamsi Krishna Kurumeti
Keyword(s):  
Diabetes Mellitus ◽  
Gestational Diabetes ◽  
Gestational Diabetes Mellitus ◽  
Pregnant Women ◽  
Thyroid Function ◽  
Thyroid Disease ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Care Hospital ◽  
High Prevalence

Background: The most common endocrine conditions encountered in pregnancy are gestational diabetes mellitus (GDM) and thyroid disease which have been known to mutually exist and impact each other to variable extents.Methods: A Cross sectional study was conducted from September 2019 to February 2020 among 150 pregnant women (75 women with GDM and 75 women without GDM) with 24-28 weeks of gestation in a tertiary care hospital. Thyroid function tests (Serum TSH, FT4 and TPO antibodies) were evaluated in all the pregnant women. All the information regarding family history of diabetes mellitus, GDM and thyroid disease was determined in both groups and analyzed by statistical methods in SPSS trial version 21.Results: Obtained data showed that TSH level (p=0.14) and anti- TPO (p=0.04) in women with GDM were more than in euglycemic pregnant women and FT4 (p≤0.001) level was lower. There is higher prevalence of hypothyroidism among GDM patients compared to that of euglycaemic women (29.3% vs 14.6%). TPO Ab was positive among 29.3% of GDM and 8% of the normal pregnant women (p<0.05). High prevalence of hypothyroidism was noticed among TPO Ab positive patients in both the groups, but more in the GDM group comparatively indicating that TPO Ab positivity is associated with a higher risk of hypothyroidism in GDM (p<0.05).Conclusions: The high prevalence of thyroid disorders and autoimmunity among GDM group warrants the importance of evaluating thyroid function in pregnant women with impaired glucose tolerance, in view of their increased risk of hypothyroidism.

Sign in / Sign up

Export Citation Format

Share Document