Widespread Osseous Metaplasia in Malign Tumors: High Grade Papillary Urothelial Carcinoma of The Bladder and Metastatic Colonic Adenocarcinoma

2016 ◽  
Author(s):  
Güldidar Basmacı ◽  
Nuket Eliyatkın ◽  
Senem Ersavaş ◽  
Hakan Postacı
Keyword(s):  
Urothelial Carcinoma ◽  
Osseous Metaplasia ◽  
High Grade ◽  
Colonic Adenocarcinoma ◽  
Papillary Urothelial Carcinoma ◽  
Carcinoma Of The Bladder

Incidentally Discovered Osseous Metaplasia Within High-grade Urothelial Carcinoma of the Bladder

Urology ◽  
2012 ◽  
Vol 79 (4) ◽  
pp. e59-e60 ◽  
Author(s):  
Anne G. Dudley ◽  
Jeffrey J. Tomaszewski ◽  
Amber H. Hughes ◽  
Benjamin J. Davies
Keyword(s):  
Urothelial Carcinoma ◽  
Osseous Metaplasia ◽  
High Grade ◽  
Carcinoma Of The Bladder

scholarly journals Seeding of a high-grade papillary urothelial carcinoma of the bladder along a nephroureterostomy tract

2017 ◽  
Vol 12 (3) ◽  
pp. 542-545 ◽  
Author(s):  
Mark Gemender ◽  
Elliot Rinzler ◽  
Gabriel Werder ◽  
Anthony P. Trace
Keyword(s):  
Urothelial Carcinoma ◽  
High Grade ◽  
Papillary Urothelial Carcinoma ◽  
Carcinoma Of The Bladder

High-grade urothelial carcinoma of the bladder with rhabdoid features: cytological and histological report of two cases

Cytopathology ◽  
2014 ◽  
Vol 26 (1) ◽  
pp. 54-56 ◽  
Author(s):  
A. Kagotani ◽  
M. Ishida ◽  
K. Yoshida ◽  
M. Iwai ◽  
H. Okabe
Keyword(s):  
Urothelial Carcinoma ◽  
High Grade ◽  
Carcinoma Of The Bladder ◽  
Rhabdoid Features

Carcinomas in the bladder with papillary and pseudopapillary morphology - not always urothelial

2020 ◽  
Vol 3 (1) ◽  
Author(s):  
Daniel Abensur Athanazio ◽  
Maiara Ferreira de Souza ◽  
Maria Estela Pompeu do Amaral
Keyword(s):  
Urinary Tract ◽  
Urothelial Carcinoma ◽  
Final Diagnosis ◽  
Prostate Adenocarcinoma ◽  
High Grade ◽  
Case Presentation ◽  
Carcinoma Prostate ◽  
Papillary Urothelial Carcinoma ◽  
Primary Bladder ◽  
Bladder Adenocarcinoma

Abstract Background Urothelial carcinoma shows wide plasticity and broad morphologic spectrum. In many instances, the presence of papillary morphology is reassuring of the urothelial histogenesis of a high-grade invasive lesion but is not pathognomonic. Case presentation We reported herein four cases of carcinomas in the bladder with papillary morphology that had a final diagnosis different from urothelial carcinoma (3% of cases in a 42-month period). In high-grade tumors involving the urinary tract, the presence of papillary/pseudopapillary morphology is not sufficient to render a diagnosis of papillary urothelial carcinoma. Prostate adenocarcinoma, primary bladder adenocarcinoma or metastasis must be excluded in selected case scenarios.

1780 FEMALE GENDER IS ASSOCIATED WITH HIGHER RISK OF DISEASE RECURRENCE IN PATIENTS WITH PRIMARY T1 HIGH GRADE UROTHELIAL CARCINOMA OF THE BLADDER

2013 ◽  
Vol 189 (4S) ◽  
Author(s):  
Luis A Kluth ◽  
Harun Fajkovic ◽  
Evanguelos Xylinas ◽  
Joseph J Crivelli ◽  
Niccolo Passoni ◽  
...  
Keyword(s):  
Urothelial Carcinoma ◽  
Female Gender ◽  
Disease Recurrence ◽  
High Grade ◽  
Risk Of Disease ◽  
Carcinoma Of The Bladder

Dermatomyositis in a patient with high grade papillary urothelial carcinoma of urinary bladder

2007 ◽  
Vol 10 (2) ◽  
pp. 153-155
Author(s):  
Aman SHARMA ◽  
Susheel KUMAR ◽  
Ajay WANCHU ◽  
A. K. MANDAL ◽  
Surjit SINGH ◽  
...  
Keyword(s):  
Urinary Bladder ◽  
Urothelial Carcinoma ◽  
High Grade ◽  
Papillary Urothelial Carcinoma

scholarly journals Recurrence and upstaging rates of T1 high-grade urothelial carcinoma of the bladder on repeat resection in a Canadian, resource-limited, healthcare system

2018 ◽  
Vol 12 (8) ◽  
Author(s):  
Adam Kinnaird ◽  
Peter Dromparis ◽  
Howard Evans
Keyword(s):  
Urothelial Carcinoma ◽  
Healthcare System ◽  
Bladder Tumour ◽  
Muscularis Propria ◽  
High Grade ◽  
Recurrence Rates ◽  
Repeat Resection ◽  
Resource Limited ◽  
Carcinoma Of The Bladder ◽  
Muscle Invasive

Introduction: Non-muscle-invasive bladder cancer is the most expensive malignancy to treat. Current Canadian guidelines recommend repeat transurethral resection of bladder tumour (TURBT) within six weeks after initial resection of T1 high-grade (T1HG) urothelial carcinoma, prior to initiation of intravesical bacillus Calmette- Guerin treatment. This is a burden on operating room usage and adds further cost and risk of complications. Internationally, major cancer centres report significant rates of recurrence and upstaging on repeat resection, however, minimal Canadian data is available. We aimed to determine the rate of recurrence and upstaging in a resource-limited, Canadian healthcare system.Methods: A retrospective review of patients receiving TURBT between November 2009 and November 2014 was performed. Patients were included if they had all three of the following: a pathological diagnosis of T1HG, adequate muscularis propria present in the specimen, and a repeat resection.Results: We reviewed 3166 patients who underwent TURBT and found 173 to meet our inclusion criteria. The overall recurrence and upstaging rates were 57.2% and 9.2%, respectively. Tumour recurrence and upstaging occurred more often in patients who had repeat resection after 12‒24 weeks compared to those patients whose repeat resection occurred within 12 weeks.Conclusions: Although recurrence rates are similar, we have found upstaging rates to be three- to four-fold lower than those previously reported. Despite this, one in 10 patients will be upstaged, justifying use of this resource within our healthcare system. Finally, timely repeat resection, within 12 weeks appears to be associated with preventing disease progression.

Umbrella Cells Mimicking Focal High-Grade Urothelial Carcinoma in Low-Grade Papillary Urothelial Carcinoma

2019 ◽  
Vol 152 (Supplement_1) ◽  
pp. S121-S121
Author(s):  
Muhammad Masood Hassan ◽  
Tammey Naab ◽  
Ali Afsari
Keyword(s):  
Urothelial Carcinoma ◽  
Proliferation Index ◽  
Low Grade ◽  
High Grade ◽  
Ki 67 ◽  
Prostate Hyperplasia ◽  
History Of ◽  
Papillary Urothelial Carcinoma ◽  
Artery Disease ◽  
Umbrella Cells

Abstract Objectives Low-grade papillary urothelial carcinoma (LGUC) has overall a preserved orderly appearance, minimal variability in architecture, and lack of significant cytologic atypia and mitotic activity without pleomorphism. A total of 53.8% of LGUC cases recur with 18.3% progression to high-grade UC. Even focal HGUC in LGUC can be a harbinger of progression. Accurate pathological interpretation is paramount in predicting recurrence and determining treatment. Methods A 63-year-old male with a past medical history of coronary artery disease, benign prostate hyperplasia, and obesity was referred to urology with a chief complaint of chronic hematuria. Cystoscopy with transurethral resection of bladder tumor was performed, which revealed mainly LGUC with focal high-grade-appearing UC. Results Histologic sections revealed papillary architecture with fused fronds, low-grade nuclear atypia, and scattered mitoses comprising 95% of the tissue submitted. No muscular wall invasion by carcinoma was seen. However, in one section, collections of large cells with well-defined cytoplasmic borders, multinucleation, and rare nuclear grooves were identified. The morphology raised the suspicion of a focal HGUC. Diffuse expression of CK20 and low Ki-67 proliferation index (1%) favored umbrella cells. Conclusion Our case reinforces the fact that sectioning can reveal foci, suspicious for HGUC, especially in urothelium. However, proper interpretation of morphology combined with the help of immunohistochemistry aids in accurate diagnosis, which is critical in determining proper clinical management of the patient.

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