scholarly journals Sjogren’s Syndrome Presenting with Central Nervous System Involvement: A Case Report

2015 ◽  
Author(s):  
Ali Taylan ◽  
Vedat Gerdan ◽  
Ferhat Ekinci
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Case Report ◽  
Sjögren’S Syndrome ◽  
Sjögren's Syndrome ◽  
Central Nervous System Involvement ◽  
Sjogren’S Syndrome ◽  
Sjogren's Syndrome ◽  
System Involvement ◽  
Sjögren‘S Syndrome

Central Nervous System Sjögren's Syndrome in a Child: Case Report and Review of the Literature

2001 ◽  
Vol 16 (9) ◽  
pp. 683-685 ◽  
Author(s):  
Jay A. Gottfried ◽  
Terri H. Finkel ◽  
Jill V. Hunter ◽  
David F. Carpentieri ◽  
Richard S. Finkel
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Case Report ◽  
Sjögren’S Syndrome ◽  
Sjögren's Syndrome ◽  
Sjogren’S Syndrome ◽  
Sjogren's Syndrome ◽  
Review Of The Literature ◽  
Sjögren‘S Syndrome

Diagnosis and management of central nervous system Sjögren's syndrome

2020 ◽  
pp. 189-209
Author(s):  
Pantelis P. Pavlakis ◽  
Theresa Lawrence–Ford ◽  
Shalini Mahajan ◽  
Janet Lewis ◽  
Arun Varadhachary ◽  
...  
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Sjögren’S Syndrome ◽  
Sjögren's Syndrome ◽  
Sjogren’S Syndrome ◽  
Sjogren's Syndrome ◽  
Diagnosis And Management ◽  
Sjögren‘S Syndrome

scholarly journals Primary peripheral T-cell central nervous system lymphoma

2021 ◽  
Vol 12 ◽  
pp. 465
Author(s):  
Cylaina E. Bird ◽  
Jeffrey I. Traylor ◽  
Jenna Thomas ◽  
James P. Caruso ◽  
Benjamin Kafka ◽  
...  
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
T Cell ◽  
Sjögren’S Syndrome ◽  
Sjögren's Syndrome ◽  
Central Nervous System Lymphoma ◽  
Sjogren’S Syndrome ◽  
Sjogren's Syndrome ◽  
History Of ◽  
Sjögren‘S Syndrome

Background: Primary peripheral T-cell central nervous system lymphoma (PCNSL) is a rare, aggressive tumor that arises in the craniospinal axis and has an increased risk in individuals who are immunocompromised. This lesion often mimics other benign and malignant processes on radiographic imaging, leading to misdiagnosis and delays in treatment. We present a case of a patient with a history of Sjögren’s syndrome and progressive neurologic symptoms who underwent craniotomy for diagnosis. Case Description: A 61-year-old woman with a history of Sjögren’s syndrome, progressive aphasia, left facial droop, and right-sided paresthesias for 4 months presented for evaluation and management. An enhancing, infiltrative lesion in the left frontal lobe with underlying vasogenic edema was appreciated and suggestive of a primary or metastatic neoplasm. The patient underwent an open biopsy for further evaluation of the lesion. Extensive histopathologic evaluation revealed a diagnosis of T-cell PCNSL. The patient was started on induction methotrexate and temozolomide followed by consolidative radiotherapy. Conclusion: Autoimmune conditions are a risk factor for T-cell PCNSL development. T-cell PCNSL has radiographic and gross histologic features that are consistent with a broad differential, including gliomas and inflammatory processes. Prompt diagnosis and extensive histopathological evaluation is essential to ensure appropriate treatment.

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