scholarly journals Evaluation Of Vascular Risk Factors İn Alzheimer’s Dementia: Clinical Experience

2012 ◽  
Vol 22 (1) ◽  
pp. 53-58
Author(s):  
Bedile İrem Tiftikcioğlu ◽  
Nilgün Tuncay ◽  
Meltem Korucuk ◽  
Yaşar Zorlu
Keyword(s):  
Risk Factors ◽  
Clinical Experience ◽  
Alzheimer’S Dementia ◽  
Vascular Risk Factors ◽  
Vascular Risk ◽  
Alzheimer's Dementia

scholarly journals Association of anxiety with vascular risk factors in memory clinic patients with MCI and Alzheimer’s dementia

2021 ◽  
Vol 17 (S6) ◽  
Author(s):  
Narges Razavian ◽  
John Dodson ◽  
Leora Horwitz ◽  
Yindalon Aphinyanaphongs ◽  
Thomas Wisniewski ◽  
...  
Keyword(s):  
Risk Factors ◽  
Alzheimer’S Dementia ◽  
Vascular Risk Factors ◽  
Vascular Risk ◽  
Memory Clinic ◽  
Alzheimer's Dementia

The Spectrum of Cerebrovascular Disease and Associated Cognitive Decline

2019 ◽  
pp. 574-599
Author(s):  
Victoria J. Williams ◽  
Steven E. Arnold ◽  
David H. Salat
Keyword(s):  
Risk Factors ◽  
Cognitive Impairment ◽  
Cerebrovascular Disease ◽  
Cognitive Decline ◽  
Vascular Dementia ◽  
Structure And Function ◽  
Vascular Risk Factors ◽  
Vascular Health ◽  
Vascular Risk ◽  
And Function

Throughout the lifespan, common variations in systemic health and illness contribute to alterations in vasculature structure and function throughout the body, significantly increasing risk for cardiovascular and cerebrovascular disease (CVD). CVD is a prevalent cause of mortality in late life; it also promotes brain alterations, contributing to cognitive decline and, when severe, vascular dementia. Even prior to diseased states, individual variation in CVD risk is associated with structural and functional brain alterations. Yet, how cumulative asymptomatic alterations in vessel structure and function contribute to more subtle changes in brain tissue integrity and function that emerge in late life is unclear. Finally, vascular risk factors are associated with the clinical progression of neurodegenerative diseases such as Alzheimer’s disease (AD); however, recent theory posits that vascular degeneration may serve a contributory role in these conditions. This chapter reviews how lifespan changes in vascular health contribute to degenerative changes in neural tissue and the subsequent development of cognitive impairment and/or vascular dementia. It first discusses associations between vascular risk factors and cognition and also how declining vascular health may lead to cognitive impairment and dementia. Next, it identifies basic aspects of cerebrovascular anatomy and physiology sustaining tissue health and discusses how vulnerabilities of this system contribute to neurodegenerative changes. Finally, it reviews evidence of vascular contributions to AD and presents ideas for future research to better understand the full spectrum of cerebrovascular contributions to brain aging, cognitive decline, and dementia.

scholarly journals The impact of vascular risk factors on the thickness and volume of the choroid in AMD patients

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Elżbieta Krytkowska ◽  
Aleksandra Grabowicz ◽  
Katarzyna Mozolewska-Piotrowska ◽  
Zofia Ulańczyk ◽  
Krzysztof Safranow ◽  
...  
Keyword(s):  
Risk Factors ◽  
Vascular Risk Factors ◽  
Age Related Macular Degeneration ◽  
Control Group ◽  
Vascular Risk ◽  
Average Volume ◽  
Central Ring ◽  
Age Related ◽  
The Impact ◽  
Wet Amd

AbstractDisturbances in choroidal microcirculation may lead to the onset and progression of age-related macular degeneration (AMD). We aimed to assess changes in the choroidal volume and thickness in the macular region in AMD eyes and to investigate whether coexisting vascular risk factors alter choroidal status. We enrolled 354 AMD patients (175 dry, 179 wet AMD) and 121 healthy controls. All participants underwent a complete ophthalmologic examination and assessment of choroidal thickness and volume. A multivariate analysis adjusted for age, sex, and smoking status revealed that wet AMD was an independent factor associated with higher average thickness of the central ring area (ATC) and average volume of the central ring area (AVC) and lower choroidal vascularity index (CVI) compared to controls (β =  + 0.18, p = 0.0007, β =  + 0.18, p = 0.0008, respectively) and to dry AMD (β =  + 0.17, p = 0.00003 for both ATC and AVC and β =  − 0.30 p < 0.0001 for CVI). ATC, AVC and average volume (AV) were lower in AMD patients with hypertension and ischaemic heart disease (IHD). The duration of hypertension was inversely correlated with ATC, AVC and AV (Rs =  − 0.13, p < 0.05; Rs =  − 0.12; p < 0.05, Rs =  − 0.12; p < 0.05, respectively) while IHD duration negatively correlated with AV (Rs =  − 0.15, p < 0.05). No such associations were observed in the control group. Our findings show that the choroidal vascular system in eyes with AMD is much more susceptible to damage in the presence than in the absence of systemic vascular disease.

scholarly journals O4-10-05: The effect of vascular risk factors on cognition in older adults: Data from the AIBL study

2012 ◽  
Vol 8 (4S_Part_17) ◽  
pp. P635-P635
Author(s):  
Carolina Restrepo ◽  
Michael Saling ◽  
Paul Yates ◽  
Victor Villemagne ◽  
David Ames ◽  
...  
Keyword(s):  
Risk Factors ◽  
Older Adults ◽  
Vascular Risk Factors ◽  
Vascular Risk

Temporal trends in vascular risk factors and etiology of urban Polish stroke patients from 1995 to 2013

2015 ◽  
Vol 357 (1-2) ◽  
pp. 126-130 ◽  
Author(s):  
Jan P. Bembenek ◽  
Michał Karlinski ◽  
Tadeusz A. Mendel ◽  
Maciej Niewada ◽  
Iwona Sarzynska-Dlugosz ◽  
...  
Keyword(s):  
Risk Factors ◽  
Temporal Trends ◽  
Vascular Risk Factors ◽  
Vascular Risk ◽  
Stroke Patients
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