scholarly journals Birth Injuries: Assessment Of Clinical Findings And Maternal, Fetal And Obstetric Risk Factors

2017 ◽  
Author(s):  
Rüya Çolak ◽  
Kazım Çoban ◽  
Kıymet Çelik ◽  
Ezgi Yangın Ergon ◽  
Senem Alkan Özdemir ◽  
...  
Keyword(s):  
Risk Factors ◽  
Clinical Findings ◽  
Birth Injuries

scholarly journals Birth Injury: Birth Asphyxia and Birth Trauma

2018 ◽  
Vol 8 (4) ◽  
pp. 788-864
Author(s):  
Kim A. Collins ◽  
Edwina Popek
Keyword(s):  
Risk Factors ◽  
Birth Asphyxia ◽  
Birth Trauma ◽  
Mechanical Trauma ◽  
Birth Injury ◽  
Permanent Damage ◽  
Severe Morbidity ◽  
Birth Injuries ◽  
Clinical Presentations ◽  
Organ Systems

Injury to a fetus or neonate during delivery can be due to several factors involving the fetus, placenta, mother, and/or instrumentation. Birth asphyxia results in hypoxia and ischemia, with global damage to organ systems. Birth trauma, that is mechanical trauma, can also cause asphyxia and/or morbidity and mortality based on the degree and anatomic location of the trauma. Some of these injuries resolve spontaneously with little or no consequence while others result in permanent damage and severe morbidity. Unfortunately, some birth injuries are fatal. To understand the range of birth injuries, one must know the risk factors, clinical presentations, pathology and pathophysiology, and postmortem autopsy findings. It is imperative for clinicians and pathologists to understand the causes of birth injury; recognize the radiographic, gross, and microscopic appearances of these injuries; differentiate them from inflicted postpartum trauma; and work to prevent future cases.

Ocular Complications

2019 ◽  
pp. 447-452
Author(s):  
James P. Dunn
Keyword(s):  
Risk Factors ◽  
Systemic Therapy ◽  
Treatment Options ◽  
Clinical Findings ◽  
Immune Recovery ◽  
Ocular Complications ◽  
Immune Recovery Uveitis ◽  
Cmv Retinitis ◽  
Symptoms And Signs

Upon completion of this chapter, the reader should be able to • Describe the symptoms and signs of cytomegalovirus (CMV) retinitis in patients with AIDS. • Describe treatment options for CMV retinitis and the need for systemic therapy whenever possible. • Identify risk factors, clinical findings, and treatment of immune recovery uveitis....

Developmental Hip Dysplasia

2019 ◽  
pp. 297-300
Author(s):  
Dorothy L. Gilbertson-Dahdal
Keyword(s):  
Risk Factors ◽  
Problem Solving ◽  
Imaging Modality ◽  
Treatment Options ◽  
Hip Dislocation ◽  
Clinical Findings ◽  
Developmental Dysplasia ◽  
Developmental Hip Dysplasia ◽  
Hormonal Factors ◽  
Dysplasia Of The Hip

Chapter 112 focuses on developmental dysplasia of the hip, which includes a spectrum of abnormalities ranging from a stable hip with a mildly dysplastic acetabulum to complete hip dislocation. Pathophysiology, clinical findings, and screening studies are explored. The pathophysiology is multifactorial including mechanical, genetic and hormonal factors. Imaging strategies, findings, and treatment options are also discussed. Screening US, which is the imaging modality of choice, is performed on infants with predisposing risk factors. Outcome is quite variable with many cases resolving spontaneously without treatment whereas others stabilize with acetabular dysplasia. Treatment options include immobilization and surgery. MRI is used for problem solving in postoperative patients.

Venous Thromboembolic Diseases

2014 ◽  
pp. 346-355
Author(s):  
Gregory Piazza ◽  
Samuel Z. Goldhaber
Keyword(s):  
Risk Factors ◽  
High Risk ◽  
Risk Stratification ◽  
Laboratory Testing ◽  
Clinical Findings ◽  
Venous Thromboembolic ◽  
Long Term Consequences ◽  
Practical Recommendations

This chapter reviews the pathophysiology of VTE, including its risk factors and long-term consequences. Diagnostic algorithms that integrate clinical findings, laboratory testing, and imaging are described. The role of risk stratification for identification of high-risk PE patients is highlighted. Options for the management of VTE are reviewed. Finally, practical recommendations for the prevention of VTE are provided.

scholarly journals Risk Factor Assessment and a Ten-Year Experience of DDH Screening in a Well-Child Population

2019 ◽  
Vol 2019 ◽  
pp. 1-6 ◽  
Author(s):  
Bahar Kural ◽  
Esra Devecioğlu Karapınar ◽  
Pınar Yılmazbaş ◽  
Tijen Eren ◽  
Gülbin Gökçay
Keyword(s):  
Risk Factors ◽  
Multiple Pregnancy ◽  
Breech Presentation ◽  
Clinical Findings ◽  
Developmental Dysplasia ◽  
Control Group ◽  
Case Group ◽  
Retrospective Case ◽  
Female Sex ◽  
Dysplasia Of The Hip

Aim. Risk based screening for developmental dysplasia of the hip (DDH) with ultrasound is common. However, risk factors vary from one country to the other since data are insufficient to give clear recommendations. We aimed to evaluate the risk factors for developmental dysplasia of the hip (DDH). Methods. In this retrospective case-control study, the health records of all children, who were followed up between 2004 and 2014 at a well-child unit, were investigated for the diagnosis of DDH in Turkey. Of 9758 children, 57 children were found to have abnormal ultrasonographic findings (according to Graf classification) and these constituted the case group. As the control group, healthy 228 children who matched the case children in birth months were selected. Two groups were compared for the risk factors. Results. A total of 19516 hips of 9758 children were examined for DDH. 97 hips of 57 children were found to have abnormal ultrasonographic findings. When the two groups were compared, breech presentation, multiple pregnancy, and torticollis were identified as risk factors. The female sex was also found to have a significantly high prevalence among the children in the case group. Limited hip abduction, positive Ortolani, and Barlow signs were important clinical findings in the case group. Conclusion. According to our findings, breech presentation, female sex, torticollis, and multiple pregnancy were found to be the risk factors of this disorder. Infants with these risk factors should be investigated carefully for DDH.

scholarly journals Predicting the Risk of Malignancy of Lung Nodules Diagnosed as Indeterminate on Radial Endobronchial Ultrasound-Guided Biopsy

2020 ◽  
Vol 9 (11) ◽  
pp. 3652
Author(s):  
Sungmin Zo ◽  
Sook-young Woo ◽  
Seonwoo Kim ◽  
Jung Eun Lee ◽  
Byeong-Ho Jeong ◽  
...  
Keyword(s):  
Risk Factors ◽  
Medical Center ◽  
Area Under The Curve ◽  
Final Diagnosis ◽  
Clinical Findings ◽  
Chest Ct ◽  
Endobronchial Ultrasound ◽  
Lung Nodules ◽  
Guided Biopsy ◽  
Risk Of Malignancy

The next diagnostic step in cases of indeterminate radial probe endobronchial ultrasound (radial EBUS)-guided biopsy results remains uncertain. This study aimed to identify risk factors for malignancy based on clinical findings, chest computed tomography (CT), and radial EBUS images, and to estimate the risk of malignancy in lung nodules that showed indeterminate radial EBUS-guided biopsy results by constructing a nomogram. This retrospective study included 157 patients with indeterminate results on an initial radial EBUS biopsy performed at the Samsung Medical Center from January 2017 to December 2018, but with a definitive final diagnosis. Medical records, chest CT, radial EBUS images, and the final diagnoses were reviewed. Patients were randomly divided into training and validation sets. Factors related to malignancy were identified through logistic regression analysis, and a nomogram was constructed using the training set and subsequently applied to the validation set. Six factors in univariable and multivariable analyses, including upper lobe location, spiculation, satellite nodules, echogenicity, presence of dots or linear arcs, and patency of vessels and bronchi predicted malignancy. A nomogram was constructed based on these predictors. The area under the curve (AUC) value of the nomogram was 0.858 using the chest CT factors, which improved to 0.952 when radial EBUS factors were added. The calibration curve showed good agreement between the actual and nomogram-predicted malignancy outcomes. The utility of radial EBUS images for revealing risk factors of malignancy was confirmed. Furthermore, our nomogram was able to predict the probability of malignancy in lung nodules with indeterminate radial EBUS-guided biopsy results.

scholarly journals Risk Factors Associated with Sleep Disturbance following Traumatic Brain Injury: Clinical Findings and Questionnaire Based Study

PLoS ONE ◽  
2013 ◽  
Vol 8 (10) ◽  
pp. e76087 ◽  
Author(s):  
Lijun Hou ◽  
Xi Han ◽  
Ping Sheng ◽  
Wusong Tong ◽  
Zhiqiang Li ◽  
...  
Keyword(s):  
Risk Factors ◽  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Sleep Disturbance ◽  
Clinical Findings ◽  
Factors Associated

scholarly journals Characteristics of Nontuberculous Mycobacterial Infections at a Midwestern Tertiary Hospital: A Retrospective Study of 365 Patients

2020 ◽  
Vol 7 (6) ◽  
Author(s):  
Claire E Hannah ◽  
Bradley A Ford ◽  
Jina Chung ◽  
Dilek Ince ◽  
Karolyn A Wanat
Keyword(s):  
Risk Factors ◽  
Mycobacterium Avium ◽  
Disease Surveillance ◽  
Mycobacterium Avium Complex ◽  
Retrospective Chart Review ◽  
Common Species ◽  
Tertiary Hospital ◽  
Population Based ◽  
Clinical Findings ◽  
Infection Prevalence

Abstract Background The prevalence of infections due to nontuberculous mycobacteria (NTM) is increasing worldwide, yet little is known about the epidemiology and pathophysiology of these ubiquitous environmental organisms. Pulmonary disease due to Mycobacterium avium complex is most prevalent, but many other NTM species can cause disease in virtually any organ system. As NTM becomes an increasingly common cause of morbidity and mortality, more information is needed about the epidemiology of NTM disease. Methods We conducted a retrospective chart review of all patients with cultures that grew NTM at a Midwestern tertiary hospital from 1996 to 2017. Information on demographics, medical history, clinical findings, treatment, and outcome was obtained from medical records of all NTM isolates. American Thoracic Society/Infectious Diseases Society of America criteria were used to define pulmonary NTM infections. Results We identified 1064 NTM isolates, 365 of which met criteria for NTM infection. Pulmonary cases predominated (185 of 365; 50.7%), followed by skin/soft tissue (56 of 365; 15.3%), disseminated (40 of 365; 11%), and lymphatic (28 of 365; 7.7%) disease. Mycobacterium avium complex was the most common species (184 of 365; 50.4%). Individuals aged >50 years were most affected (207 of 365; 56.7%). Common comorbidities included structural lung disease (116 of 365; 31.8%), use of immunosuppressive medications (78 of 365; 21.4%), malignancy (59 of 365; 16.2%), and human immunodeficiency virus (42 of 365; 11.5%). Conclusions This large cohort provides information on the demographics, risk factors, and disease course of patients with pulmonary and extrapulmonary NTM infections. Most patients had medical comorbidities that resulted in anatomic, genetic, or immunologic risk factors for NTM infection. Further population-based studies and increased disease surveillance are warranted to further characterize NTM infection prevalence and trends.

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