scholarly journals Comparison of Antibiotic Resistance Patterns Between AmpC Producers, ESBL Producers, AmpC and ESBL Coproducers of Cefoxitin-insusceptible Clinical Isolates of Escherichia coli and Klebsiella pneumoniae

ANKEM Dergisi ◽  
2012 ◽  
Vol 25 (4) ◽  
pp. 244-249
Author(s):  
Serpil Coskun ◽  
Nurten Altanlar
Keyword(s):  
Escherichia Coli ◽  
Antibiotic Resistance ◽  
Klebsiella Pneumoniae ◽  
Clinical Isolates ◽  
Resistance Patterns ◽  
Antibiotic Resistance Patterns ◽  
Esbl Producers

scholarly journals Incidence of ?-lactamase producing Escherichia coli amongst clinical isolates in Dhaka, Bangladesh

2016 ◽  
Vol 5 (1) ◽  
pp. 18-21
Author(s):  
Anindita Bhowmik ◽  
Sunjukta Ahsan ◽  
Marufa Zerin Akhtar ◽  
Md Shahidul Kabir
Keyword(s):  
Escherichia Coli ◽  
Antibiotic Resistance ◽  
Point Of View ◽  
Clinical Isolates ◽  
Clinical Samples ◽  
Drug Of Choice ◽  
Resistance Patterns ◽  
Lactam Antibiotic ◽  
Antibiotic Resistance Patterns

Escherichia coli is one of the most important clinical pathogens that demonstrate antibiotic resistance through their ? -lactamase activity. The present study reflected on the presence of ?-lactam antibiotic resistance in clinical samples. Antibiotic resistance patterns of 20 clinical isolates of Escherichia coli against ? -lactam antibiotics were investigated. These isolates were collected from a hospital in Dhaka city and MIC values were determined against Imipenem, Cefotaxime and Ceftriaxone. In case of Ceftriaxone the highest MIC was >4096 ?g/mL for 50% isolates with a minimum MIC of 1 ?g/ml for 10% isolates. In case of Cefotaxime, MIC values ranged between 1 ?g/ml and >4096 ?g/ml for 20% and 10% isolates, respectively. In contrast, 80% of the isolates had an MIC of Imipenem at 1 ?g/mL with only 5% isolate having MIC of 8 ?g/mL. Eight out of 20 (40%) isolates were ESBL producers, 14 (70%) were ? -lactamase producers. Two isolates exhibited ESBL activity against Cefotaxime and Ceftriaxone, 3 against only Cefotaxime and 3 against only Ceftriaxone. Ceftriaxone resistance in 10 randomly picked isolates was found to be stable for 21days in stability assay. Considering the findings of the present study, it appears that Imipenem still remains the drug of choice for E. coli infections; alternatively, combination therapy may be prescribed. In vitro stability of Ceftriaxone resistance raises concern from a public health point of view as this may aid antibiotic resistance transfer to other bacteria in the environment.Stamford Journal of Microbiology, Vol.5(1) 2015: 18-21

scholarly journals Differential Etiological Profiles and Antibiotic Resistance Patterns of Urinary Tract Infection Among Different Age Categories: A Retrospective Study from a Tertiary General Hospital During a 12-Year Period

2021 ◽  
Author(s):  
Lei Huang ◽  
Chenwei Huang ◽  
Yan Yan ◽  
Liying Sun ◽  
Haixia Li
Keyword(s):  
Escherichia Coli ◽  
Antibiotic Resistance ◽  
Urinary Tract ◽  
Klebsiella Pneumoniae ◽  
General Hospital ◽  
Enterococcus Faecalis ◽  
Enterococcus Faecium ◽  
Resistance Patterns ◽  
Resistance Rates ◽  
Antibiotic Resistance Patterns

Abstract Background: Urinary tract infections (UTIs) are among the most common infections worldwide. With continuing trends of antibiotic resistance, the etiological distribution and antibiotic susceptibility surveillance are of great importance for empirical antimicrobial therapy. However, the data may change with different ages. The aim of this study was to compare the etiological profiles and antibiotic resistance patterns of UTIs sorted by different age categories from a tertiary general hospital during a 12-year period.Methods: All positive urine culture results from non-repetitive UTI patients in our hospital from January 2009 to December 2020 were collected retrospectively. The microbial distribution and antibiotic resistance rates were analyzed by WHONET 5.6 software. The etiological profiles sorted by different age categories (newborn, pediatric, adult, and geriatric) and antibiotic resistance rates of the top 5 pathogens were analyzed.Results: A total of 13308 non-repetitive UTI patients were included in our study. Enterococcus faecium was dominant in newborn, and replaced by Escherichia coli in other age categories. The etiological profiles of different age categories were divergent, sorted by genders (male and female) and ward types (outpatient, in-patient, ICU, and emergency). Escherichia coli, Klebsiella pneumoniae, Enterococcus faecalis, Enterococcus faecium, and Pseudomonas aeruginosa were the top 5 pathogens in all age categories. The resistance rates of cefperazone-sulbactam and piperacillin-tazobactam in Escherichia coli were low in all age categories. The resistance rates of cephalosporins, carbapenems, and fluoroqinolones in Klebsiella pneumoniae were higher in geriatric patients overall. Enterococcus faecium was more resistant than Enterococcus faecalis in all age categories.Conclusions: The UTI etiological profiles and antibiotic resistance patterns were divergent among different age categories, thus different empirical antibiotic therapies should be considered for different ages.

Occurrence of Enteropathogenic Escherichia coli Serotypes in Butter

1987 ◽  
Vol 50 (10) ◽  
pp. 829-831 ◽  
Author(s):  
F. M. ABBAR ◽  
M. TAHIR MOHAMED
Keyword(s):  
Escherichia Coli ◽  
Antibiotic Resistance ◽  
Fecal Coliforms ◽  
Enteropathogenic Escherichia Coli ◽  
Heat Stable ◽  
Resistance Patterns ◽  
Antibiotic Resistance Patterns

A total of 30 samples of butter analysed during the course of the investigation showed that fecal coliforms were absent from only 13.3% of samples. One hundred forty colonies of fecal coliforms were biochemically characterized with the following types obtained (Escherichia sp. 41.4%, Enterobacter sp. 25.7%, Citrobacter sp. 20%, Klebsiella sp. 10%). Five different serotypes, namely 0 125 K70(2), 0 142K86(1), 0 127K63(1), 0 114 K90(2), 0 111 K58(1) were detected in 7 of 58 Escherichia coli isolates and 51 strains were untypable. Three strains produced heat stable (ST) enterotoxin and belonged to the enteropathogenic serotype. The antibiotic resistance patterns of coliform strains are presented.

scholarly journals Molecular Detection of Avian Pathogenic Escherichia coli (APEC) for the First Time in Layer Farms in Bangladesh and Their Antibiotic Resistance Patterns

2020 ◽  
Vol 8 (7) ◽  
pp. 1021 ◽  
Author(s):  
Samina Ievy ◽  
Md. Saiful Islam ◽  
Md. Abdus Sobur ◽  
Mithun Talukder ◽  
Md. Bahanur Rahman ◽  
...  
Keyword(s):  
Escherichia Coli ◽  
Antibiotic Resistance ◽  
Virulence Genes ◽  
Molecular Detection ◽  
Avian Pathogenic Escherichia Coli ◽  
Internal Organs ◽  
Pathogenic Escherichia Coli ◽  
Resistance Patterns ◽  
Antibiotic Resistance Patterns ◽  
First Time

Avian pathogenic Escherichia coli (APEC) causes significant economic losses in poultry industries. Here, we determined for the first time in Bangladesh, the prevalence of APEC-associated virulence genes in E. coli isolated from layer farms and their antibiotic resistance patterns. A total of 99 samples comprising internal organs, feces, and air were collected from 32 layer farms. Isolation was performed by culturing samples on eosin–methylene blue agar plates, while the molecular detection of APEC was performed by PCR, and antibiograms were performed by disk diffusion. Among the samples, 36 were positive for the APEC-associated virulence genes fimC, iucD, and papC. Out of 36 isolates, 7, 18, and 11 were positive, respectively, for three virulence genes (papC, fimC, and iucD), two virulence genes, and a single virulence gene. Although the detection of virulence genes was significantly higher in the internal organs, the air and feces were also positive. The antibiograms revealed that all the isolates (100%) were resistant to ampicillin and tetracycline; 97.2%, to chloramphenicol and erythromycin; 55.5%, to enrofloxacin; 50.0%, to norfloxacin and ciprofloxacin; 19.4%, to streptomycin; 11.1%, to colistin; and 8.33%, to gentamicin. Interestingly, all the isolates were multidrug-resistant (MDR). Spearman’s rank correlation coefficient analysis revealed the strongest significant correlation between norfloxacin and ciprofloxacin resistance. This is the first study in Bangladesh describing the molecular detection of APEC in layer farms. Isolated APEC can now be used for detailed genetic characterization and assessing the impact on public health.

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