Evaluation of Candidal Carriage Among Smokers and Non-Smokers

2020 ◽  
Vol 10 (4) ◽  
pp. 266-270
Author(s):  
Umar Irfan ◽  
Salik Rasool ◽  
Perveen Memon ◽  
Shazia Irum ◽  
Bushra Jabeen ◽  
...  

Objectives: To determine the Candidal carriage among smokers and non-smokers and with different intra-oral sites including examination of various biotypes of Candida. Study design and setting: Cross-sectional based study conducted at Dr. Ishrat ul Ebad Khan Institute of Oral Health Sciences and Dow International Dental College, Karachi, from May 2017 till April 2018. Methodology: Comprised 100 patients (50 smokers and 50 nonsmokers) between 20 and 60 years of age. The collection was performed through sterile cotton swab to evaluate oral Candidal carriage and the colonizing Candida species using Sabouraud Dextrose Agar (SDA) and API20C AUX (BIOMERIEUX). Data was analyzed Spss version 20. Results: A total of 100 participants (50 smokers and 50 non-smokers) were evaluated for candidal carriage. The common age group was 20-30 years in both the groups, without significant difference (p-value 0.79). Frequency of candidal carriage was comparable among smokers 14 (28.0%) to non-smokers 10 (20.0%), with a statistically insignificant p-value 0.35. Based on various biotypes among smokers and non-smokers, Candida albicans was 9(18%) and 7(14%), Candida glabrata was 4(8%) and 2(4%); and Candida tropicallis was 1(2%) each for both smokers and non smokers. Dorsum of tongue harbored all prevalent biotypes i.e. Candida albicans, Candida glabrata and Candida tropicalis as statistically significant among smokers (p-value 0.04). Conclusion: Candidal carriage was comparable among smokers and non-smokers. Candida albicans and Candida glabrata were the common biotypes predominantly among smokers

Author(s):  
Atul V. Rajkondawar ◽  
Amit Yele

Background: Chronic kidney disease (CKD) remains one of the major health problems in India. Renal function steadily deteriorates as age advances and advancing age has been indicted to have adverse implications in the disease progression to end stage renal disease (ESRD). With the present study, clinico-biochemical profiling of chronic kidney disease patients in geriatric age group as well as comparison with non-elderly patients was undertaken.Methods: In this cross-sectional observational study, 100 patients of CKD admitted in the tertiary care study centre were enrolled consecutively and assessed for symptoms, signs and biochemical parameters over two years. Study subjects were divided into two groups:- Group 1: Elderly patients- aged 60 years or more, and Group 2: Non-elderly patients- less than 60 years of age. Relevant comparisons were drawn statistically and tested for significance.Results: Pallor and pedal edema were observed to be the commonest clinical features across groups. Elderly group shows higher prevalence of severe anaemia (mean hemoglobin- 7.4 gm%). Higher prevalence of clinical and biochemical derangement was found in patients with relatively lower GFR. Elderly age group also had more prevalence of electrolyte abnormalities compared with non-elderly population, with statistically significant difference observed for hyponatremia (p value- 0.023), hypoproteinemia (p value- 0.0078) and blood urea level (p value- 0.0054).Conclusions: Understanding beforehand the biochemical abnormalities associated with old age in CKD patients helps in appropriate modifications in patient management.


2020 ◽  
Vol 23 (1) ◽  
pp. 32-40
Author(s):  
Syed Mohammed Tipu Sultan ◽  
Md Abdus Sattar ◽  
Mahiuddin Khan ◽  
Zahedul Alam ◽  
Golam Mostafa ◽  
...  

Introduction: Epistaxis is a common problem which may affect all age groups. It has bimodal presentation.Nontraumatic epistaxis may affect more frequently among older male. Objective: It is important to observe the common factors related with the different etiological types of epistaxis. It is also important to observe the various socio demographic characteristic of the patient with pattern of presentation of the epistaxis. Mehods: Cross-sectional study in tertiary level hospital. From July 2012 to June 2013, 176 participants were selected. Results: Traumatic epistaxis was more frequent (70.51%) among younger age group (age <45yeras), whereas non-traumatic epistaxis was more frequent (72.92%) among older age group (age >45yeras). There was a statistically significant difference between the different age group with their etiology of the epistaxis (P = <0.001). Bangladesh J Otorhinolaryngol; April 2017; 23(1): 32-40


Author(s):  
Fauzia Aamer

Introduction: Bleeding issues specific to women and adolescent females are common across the world. These issues can present either due to gynecological causes or obstetric one; however these can result in significant morbidity and work up needs to be done to rule out any underlying bleeding diathesis. Aims & Objectives: To determine frequency of various bleeding disorders among gynecological and obstetric patients presenting with bleeding. Place and duration of study: It is a cross sectional study which was conducted in the Hematology Department, Services Institute of Medical Sciences, Lahore. The duration of study was 6 months i.e from 21st Oct, 2018 to 30th April, 2019. Material & Methods: Females with age range of 15 to 50 years irrespective of pregnancy presenting as menorrhagia, metrorrhagia or obstetrical bleeding were included. Results: In the present study there were total 140 cases with mean age of 30.14±9.59 years. There were 98 (70%) cases that were pregnant. There were 35 (25%) cases presented with PPH (Post Partum Hemorrhage), 42 (30%) with IPH (Intra Partum Hemorrhage), 49 (35%) with menorrhagia and 14 (10%) with metrorrhagia. HELLP (Hemolysis, Elevated Liver enzymes and Low Platelet count) syndrome was seen in 13 (9.29%) cases, DIC (Disseminated Intravascular Coagulation) in 2 (1.43%), gestational thrombocytopenia in 7 (5%), while factor deficiency in 34 (24.29%) cases; and 84 (60%) of cases revealed none of the bleeding disorder. Out of total 34 cases of factor deficiencies, vWD was the most common, seen in 20 (58.82%) cases. There was none of the cases seen having deficiency of factor II, VII, VIII, XI, XII. HELLP syndrome was seen in 11 (84.62%) of the cases with age group 15 to 32 years and similarly both cases of DIC were seen in same age group; but the difference in both the age groups regarding these bleeding disorders was not statistically significant with p= 0.38. There was no significant difference in terms of pregnancy; however, both cases of DIC were seen in pregnancy with insignificant p value of 0.51. HELLP syndrome was more seen in IPH affecting 5 (38.40%), factor deficiency in menorrhagia affecting 13 (38.2%) with p value of 0.61. vWD and factor V Leiden presented in 44.4% cases each with PPH, and vWD affected 87.5% of cases in IPH without any significant difference with p= 0.42. Conclusion: Bleeding disorders are not uncommon in gynecological and obstetric conditions. Factor deficiency were the most common causes and amongst these vWD was the most deficient factor. There was no significant association with any confounding variable; however, DIC was only seen in obstetrical conditions. Key words: Bleeding, menorrhagia, HELLP, DIC, IPH, PPH


Author(s):  
KS Manjula ◽  
R Reena ◽  
Swapna Jaswanth ◽  
SMR Usha

Introduction: Higher prevalence of thyroid diseases are noted with increasing age. Symptoms of thyroid disorders often develop so insidiously, that they go unnoticed and there is also the risk of being misinterpreted for menopausal symptoms. Present study was executed in view of paucity of data regarding thyroid disorders among tribal perimenopausal age group and there was a need for timely intervention of this chronic non-communicable disorder among these women. Aim: To determine the thyroid function and anti-Thyroid Peroxidase Antibody (anti-TPO Ab) status among the tribal perimenopausal women. Materials and Methods: A descriptive, cross-sectional study was conducted for a period of six months from July 2017 to December 2017 among perimenopausal women in the age group of 40-55 years residing at Hakki Pikki Tribal Colony near Bengaluru, Karnataka, India. Thyroid Stimulating Hormone (TSH), Total T3 (Total Tri iodothyronine), Total T4(Total Tetraidiodothyronine) and anti-TPO antibody levels were estimated by Chemiluminescence Immuno Assay (CLIA). Data was analysed using Open Epi software to find out Mean±SD, p-value (Student’s t-test with significance set at p<0.05) and r-value (Pearson’s correlation coefficient). Results: Subclinical Hypothyroidism (SCH) was observed in 3 (7.32%) women and anti-TPO Ab positivity (anti-TPO antibody level >30 IU/mL) was found in 14 (34.14%) women amongst 41 perimenopausal subjects. Raised anti-TPO Ab was observed in all the 3 (100%) SCH women and 11 (26.82%) euthyroid women. Significant difference (p<0.001) between anti-TPO Ab values among SCH and euthyroid women with significant positive correlation (r-value 0.7023 and p<0.05) between TSH and anti-TPO Ab values in anti-TPO Ab positive women was noted. Conclusion: Anti-TPO Ab positivity was seen in 34% of perimenopausal women, out of them majority 79% was in euthyroid state and 21% had SCH. Hence in addition to routine thyroid profile, we suggest estimation of anti-TPO Ab levels in this age group.


2021 ◽  
Vol 15 (6) ◽  
pp. 1285-1288
Author(s):  
M. J. A . Zahrani ◽  
S. H. Qahtani ◽  
W. A. Baig ◽  
F. S. Alasmari

Background: Awareness and knowledge about prevention of infections are important to prevent transmission of diseases from healthcare workers to patients. Aim: To evaluate the students’ attitude towards infection control at Prince Sultan Military College of Health Sciences, Dhahran, Saudi Arabia. Study Design: Cross sectional study. Methodology: Present study enrolled 415 participants involving both genders from different allied health specialties at PSMCHS. A standardized, anonymous online questionnaire was utilized to gather the data necessary to assess students’ attitudes through answering seven statements. Informed written consent was taken. Unwilling participants were excluded. All collected information was kept confidential. Data analyzed by SPSS 25.0. Frequency and percentage were given for gender distribution and knowledge assessment through questionnaire. Moreover, F- test was applied by keeping CI (95%) with p-value of ≤ 0.05 taken as significant. Results: There was a significant difference between female and male students regarding the positive attitude towards infection control. Dental and Oral Health students scored the highest degree of agreement using Analysis of Variance (F-test). This high score was obtained because dedicates an entire course infection control while it was embedded in the other departments’ courses. Conclusion: This study concluded that a dedicated course on infection control was an effective tool in instilling positive attitude towards infection control among PSMCHS students from different specialties. Keywords: Attitude, Awareness, Infection control and Students.


2017 ◽  
Vol 5 (1) ◽  
pp. 226
Author(s):  
Kumarasamy Kalyanasundaram ◽  
Harikrishnan Elangovan ◽  
Madhivanan Sailavasan

Background: Acute Renal Failure (ARF) is one of the common causes of morbidity and mortality in children. With the availability of increasing knowledge and awareness, dialysis facilities and excellent supportive treatment, the overall outcome is changing. This study is undertaken to find out the outcome of ARF in children.Methods: This prospective cross-sectional study was done in Institute of Child Health and Hospital for Children, (ICH and HC) Egmore, Chennai from February 2014 to January 2016. Children with elevated blood urea (>40 mgs/dl) and serum creatinine (>1 mg/dl) were included and evaluated for etiology, treatment modality and outcome and other co-morbid features. Data was analysed on SPSS 20.0. P value of <0.05 was considered significant.Results: A total of 105 children (65 boys, 40 girls) from newborn period to 12 years were examined. The common age of presentation of ARF is 1-4 years with a male preponderance and acute glomerulonephritis were found to be commonest cause. There was no statistically significant difference in mortality in relation to age group (P 0.98). There was a statistically significant difference in mortality in relation to duration of oliguria (P 0.02), Serum creatinine levels (P 0.03). The role of other biochemical values like serum potassium (P 0.14), serum bicarbonate (P 0.59) were not found statistically significant. Peritoneal dialysis in general improves survival, but it is not statistically significant (P 0.33). Systemic complications associated with ARF increases mortality and it is statistically significant (Chi- square value = 9.13, P = 0.003).Conclusions: ARF in children is due to transient disorders and early referral to major centres even with 1-2 days oliguria and early treatment will improve the prognosis. Peritoneal dialysis in severe ARF with associated complications really helped the children.


2018 ◽  
Vol 1 (2) ◽  
pp. 114
Author(s):  
Wahdaniah Wahdaniah ◽  
Sri Tumpuk

Abstract: Routine blood examination is the earliest blood test or screening test to determine the diagnosis of an abnormality. Blood easily froze if it is outside the body and can be prevented by the addition of anticoagulants, one of which Ethylene Diamine Tetra Acetate (EDTA). Currently available vacuum tubes containing EDTA anticoagulants in the form of K2EDTA and K3EDTA. K3EDTA is usually a salt that has better stability than other EDTA salts because it shows a pH approaching a blood pH of about 6.4. The purpose of this research is to know the difference of erythrocyte index results include MCH, MCV and MCHC using K3EDTA anticoagulant with K2EDTA. This research is a cross sectional design. This study used venous blood samples mixed with K2EDTA anticoagulant and venous blood mixed with K3EDTA anticoagulants, each of 30 samples. Data were collected and analyzed using paired different test. Based on data analysis that has been done on MCH examination, p value <0,05 then there is a significant difference between samples with K3EDTA anticoagulant with K2EDTA to erythrocyte index value. Then on the examination of MCV and MCHC obtained p value <0.05 then there is no significant difference between samples with K3EDTA anticoagulant with K2EDTA to erythrocyte index value.Abstrak: Pemeriksaan darah rutin merupakan pemeriksaan darah yang paling awal atau screening test untuk mengetahui diagnosis suatu kelainan. Darah mudah membeku jika berada diluar tubuh dan bisa dicegah dengan penambahan antikoagulan, salah satunya Ethylene Diamine Tetra Acetate (EDTA). Dewasa ini telah tersedia tabung vakum yang sudah berisi antikoagulan EDTA dalam bentuk  K2EDTA dan  K3EDTA. K3EDTA  biasanya berupa garam yang mempunyai stabilitas yang lebih baik dari garam EDTA yang lain karena menunjukkan pH yang mendekati pH darah yaitu sekitar 6,4. Tujuan dari penelitian ini adalah untuk mengetahui perbedaan hasil indeks eritrosit meliputi MCH, MCV dan MCHC menggunakan antikoagulan K3EDTA dengan K2EDTA. Penelitian ini merupakan penelitian dengan desain cross sectional. Penelitian ini menggunakan sampel darah vena yang dicampur dengan antikoagulan K2EDTA dan darah vena yang dicampur dengan antikoagulan K3EDTA, masing-masing sebanyak 30 sampel. Data dikumpulkan dan dianalisis menggunakan uji beda berpasangan. Berdasarkan analisis data yang telah dilakukan pada pemeriksaan MCH didapatkan nilai p < 0,05 maka ada perbedaan yang signifikan antara sampel dengan antikoagulan K3EDTA dengan K2EDTA terhadap nilai indeks eritrosit. Kemudian pada pemeriksaan MCV dan MCHC didapatkan nilai p < 0,05 maka tidak ada perbedaan yang signifikan antara sampel dengan antikoagulan K3EDTA dengan K2EDTA terhadap nilai indeks eritrosit.


2020 ◽  
Vol 2 (CSI) ◽  
pp. 12-18
Author(s):  
Ali Al-Rubaye ◽  
Dhurgham Abdulwahid ◽  
Aymen Albadran ◽  
Abbas Ejbary ◽  
Laith Alrubaiy

Background: There has been a rapid rise in cases of COVID-19 infection and its mortality rate since the first case reported in February 2020. This led to the rampant dissemination of misinformation and rumors about the disease among the public. Objectives: To investigate the scale of public misinformation about COVID-19 in Basrah, Iraq. Methods: A cross-sectional study based on a 22-item questionnaire to assess public knowledge and understanding of information related to the COVID-19 infection. Results: A total of 483 individuals completed the questionnaire. The most frequent age group was 26–35 years (28.2%); there were 280 (58%) males and 203 (42%) females. Of the participants, 282 (58.4%) were with an education level below the Bachelor’s degree, 342 (70.8%) were married, and 311 (64%) were living in districts in Basra other than the central district. Overall, 50.8% (11.8/ 22 * 100%) of individuals had the correct information regarding COVID-19. There was a significant association between the level of COVID-19 related misinformation and participants’ educational levels and occupation (p <0.05). However, there was no significant difference found across sex, age group, marital state, and area of residence. Conclusions: Misinformation related to COVID-19 is widely spread and has to be addressed in order to control the pandemic. Keywords: COVID-19, misinformation, knowledge, Iraq


Work ◽  
2021 ◽  
pp. 1-8
Author(s):  
Javad vatani ◽  
Zahra Khanikosarkhizi ◽  
Mohammad Ali Shahabi Rabori ◽  
mohammad khandan ◽  
Mohsen aminizadeh ◽  
...  

BACKGROUND: Safety climate is a common insight of staff that indicates individuals’ attitudes toward safety and priority of safety at work. OBJECTIVES: Nursing is a risky job where paying attention to safety is crucial. The assessment of the safety climate is one of the methods to measure the safety conditions in this occupation. The aim of this study was to assess the safety climate of rehabilitation nurses working in hospitals in Tehran. METHODS: This is a cross-sectional study which was carried out on 140 rehabilitation nurses selected from all hospitals and clinics in Tehran in 2019. To collect the required data, a two-section questionnaire was used. The first section was related to demographic factors and the second part (22 statements) was to measure the safety climate using nurses’ safety climate assessment questionnaire. The collected data were analyzed by SPSS V16 using independent t-test, ANOVA, Kruskal-Wallis and Mann-Whitney U test at the 5% level. RESULTS: Findings showed that the total mean of safety climate was 3.06±0.56. According to the results, a significant difference was found between the positive and negative satisfaction of nurses with safety climates (P-value = 0.03), communication with nurses (P-value = 0.01) and supervisors’ attitude (P-value = 0.02). Furthermore, a significant difference in safety climate between the individual with the second job and the individual without second could be observed (P-value = 0.01). CONCLUSIONS: The results indicated that the safety climate was not at an acceptable level. Thus, it is essential to introduce safety training courses (e.g. safety, work-rest balance, and so on) and to improve the safety performance at work.


2021 ◽  
Vol 11 (02) ◽  
pp. 65-69
Author(s):  
Maria Shakoor Abbasi ◽  
Naseer Ahmed ◽  
Azad Ali Azad ◽  
Fatima Fouad ◽  
Humza Daudpota ◽  
...  

Objectives: To assess the concepts of complete denture occlusion among dental fraternity. Study Design And Setting: Cross-sectional study conducted at various dental hospitals and institutes of Karachi, for a period of six months, from 1st June’2019 to 30th November’2019 Methodology: Total 849 dental practitioners who are currently practising were included. A well-structured and validated questionnaire was used for data collection. SPSS version 25 was used. Results: Bilateral balanced occlusion was an ideal occlusion by majority subjects i.e, 530(62.4%) in patients with wellformed ridges, followed by 464(54.7%) candidates with skeletal class 1, total 376(44.3%) chose it with uncontrolled diabetes mellitus, 365(43%) in single complete denture cases, 339(39.9%) with increased inter-arch space, 298(35.1%) with parafunction habits, 296(34.9%) in patients with history of neuromuscular disorder and 271(31.9%) where a complete denture opposes a removable partial denture. Furthermore, Lingualized occlusion was preferred by 341(40.25%) participants for patients with skeletal class 3. Total 316(37.2%) candidates chose it for patients with displaceable supporting tissue followed by 264(31.1%) who chose it for skeletal 2 and 260(30.6%) for cases of highly resorbed ridges. Lastly, 311(36.6%) chose canine guided occlusion with highly resorbed ridges accompanied by high aesthetic demand A significant difference between education level and knowledge of occlusal schemes was also found. Chi-square (73.87), df 6, p-value =0.000. Conclusion: Dental practitioners lack adequate knowledge of occlusal schemes in terms of prescription in complete denture patients. A significant difference between the education level and knowledge of occlusal schemes was found. Therefore, awareness of various occlusal schemes should be increased at undergraduate level.


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