scholarly journals Quantitative Assessment Of The Variations In Thyroid Dimensions In Relation To Increase In Serum TSH In Euthyroids

2018 ◽  
Vol 08 (02) ◽  
pp. 72-76
Author(s):  
Mahrukh Kamran ◽  
Sahar Mubeen ◽  
Iffat Raza ◽  
Sanobar Bughio ◽  
Hira Waseem ◽  
...  
Keyword(s):  
Total Variation ◽  
Cross Sectional Study ◽  
Thyroid Stimulating Hormone ◽  
Left Lobe ◽  
University Hospital ◽  
P Value ◽  
Cross Sectional ◽  
Right Lobe ◽  
The Right ◽  
Serum Tsh

Objectives: To determine the effect of serum TSH on thyroid dimensions of each lobe and to measure the amount of effect of per unit increase in serum TSH on thyroid dimensions of each lobe in euthyroids. Study Design: It was a cross-sectional study. Setting: The study was conducted at Ziauddin University Hospital, Clifton, Karachi. Methodology: Healthy participants aged 21 years and above were included through convenient sampling. Serum Thyroid stimulating hormone was evaluated and ultrasound of thyroid gland TG of 192 euthyroid participants was performed. Spearman correlation and regression analysis was applied to evaluate the relationship between TSH and TG dimensions Results: Relationship of increase in serum TSH with decrease in light lobe AP dimension was most significant. (r= -0.142 P-Value=0.001) and CC dimension least significant (r= -0.0098 P-Value=0.001). Where as in the left lobe AP dimension decreases significantly with increase serum TSH (r= -0.147 P-value=0.001). 11.7% of total variation in AP dimension, 3.5% of total variation in ML dimension and 6.5% of total variation in CC dimension in right lobe thyroid are because of serum TSH. While 9.5% of the total variation in AP dimension in left lobe is also due to serum TSH. Conclusion: Negative and significant correlation between serum TSH and thyroid dimensions was observed. Serum TSH inversely and significantly affects all the dimensions of the right lobe and only one dimension in the left lobe

scholarly journals Recurrent Miscarriage and Consanguinity among Omani Women– A Cross Sectional Study

2021 ◽  
Vol 5 (1) ◽  
Author(s):  
Fatma Al Hoqani ◽  
Wadha Al Ghafri ◽  
Saneya El tayeb ◽  
Yahya Al Farsi ◽  
Vaidyanathan Gowri
Keyword(s):  
Recurrent Miscarriage ◽  
Cross Sectional Study ◽  
University Hospital ◽  
Control Group ◽  
P Value ◽  
Cross Sectional ◽  
Recurrent Miscarriages ◽  
Sultan Qaboos University ◽  
Chi Squared ◽  
History Of

Objective: to determine the prevalence of explained and unexplained recurrent miscarriages (RM) and to find out if there is a significant relationship between recurrent miscarriages and consanguinity. Methods: A cross sectional in which the cases group included all women with RM attending the outpatient clinic at Sultan Qaboos University Hospital from July 2006 to April 2012 and the controls group included women with no history of RM after matching them with cases for age (case to control ratio was 1:1). The main outcome measures were the prevalence of consanguinity in women with or without recurrent miscarriages. Results: During study period a total of 290 women with RM were seen. Of which, 150 (51.7%) women had unexplained RM. Control group with no history of RM were 300 women. Consanguinity rate among cases (49.5%) %) was less than the controls (52.7 %%). Both first cousin and second cousin marriages were more common in the controls than the cases and it was not statistically significant (p value 0.476, chi squared test). Conclusion: In this study we found that more than half of RM cases were unexplained and there was no significant association between RM and consanguinity.

scholarly journals Thyroid dysfunction in patients of metabolic syndrome: A study from a tertiary care center in India

2021 ◽  
Vol 12 (10) ◽  
pp. 47-50
Author(s):  
Ritu Gupta ◽  
Akhil K Vijayan ◽  
Sushma Choudhary
Keyword(s):  
Metabolic Syndrome ◽  
Thyroid Dysfunction ◽  
Care Center ◽  
Tertiary Care ◽  
Cross Sectional Study ◽  
Thyroid Stimulating Hormone ◽  
P Value ◽  
Overt Hypothyroidism ◽  
Free T4 ◽  
Cross Sectional

Background: Metabolic syndrome is characterized by hypertension, dyslipidemia, central obesity, glucose intolerance, insulin resistance. Thyroid hormone acts as general pacemaker, accelerating metabolic process and may be associated with metabolic syndrome. There is no information available in literature regarding the prevalence and association of thyroid dysfunction in metabolic syndrome in this central region of the country. Aims and Objective: To estimate the prevalence of thyroid dysfunction in patients of metabolic syndrome. Materials and Methods: It is a duration based prospective cross sectional study including 200 patients of metabolic syndrome. A detailed history, clinical examination and relevant investigations including serum Free T4 (FT4), Free T3 (FT3), Thyroid Stimulating Hormone (TSH) were done. Range, frequencies, percentage, mean, standard deviation and P value were calculated. P value of < 0.05 was taken as significant. Results: Prevalence of thyroid dysfunction in metabolic syndrome patients was 28.5%. Prevalence of subclinical and overt hypothyroidism was 18.5% and 8.5% respectively. In patients with both metabolic syndrome and thyroid dysfunction, most common components associated are diabetes mellitus and hypertriglyceridemia. Conclusion: Thyroid dysfunction is significantly common in metabolic syndrome patients. It should be aggressively detected and treated in these patients for better outcome.

scholarly journals EFFECT OF PREANALYTICAL VARIABLES ON SERUM THYROID STIMULATING HORMONE ANALYSIS BY CHEMILUMINESCENCE METHOD

2021 ◽  
Vol 71 (Suppl-1) ◽  
pp. S102-05
Author(s):  
Ambreen Rehman ◽  
Naveed Asif ◽  
Saima Shakeel Malik ◽  
Waqas Sheikh ◽  
Quratulain . ◽  
...  
Keyword(s):  
Venous Blood ◽  
Armed Forces ◽  
Epidemiological Studies ◽  
Cross Sectional Study ◽  
Thyroid Stimulating Hormone ◽  
P Value ◽  
Cross Sectional ◽  
Specimen Handling ◽  
Tsh Levels ◽  
Stimulating Hormone

Objective: To identify effect of pre-analytical variables on serum thyroid stimulating hormone. Study Design: Cross sectional study. Place and Duration of Study: Armed Forces Institute of Pathology (AFIP) Rawalpindi, Department of Chemical Pathology & Endocrinology, from Mar 2018 to Aug 2018. Methodology: Hundred subjects with ages ranging from 18 to 34 years, irrespective of gender, were randomly selected for this study. Five milliliters venous blood sample was collected from each subject in a serum separator and divided into two aliquots. First aliquot was centrifuged and analyzed immediately for TSH, while second aliquot was stored for 24 hours and was then analyzed. TSH was measured by third generation assay usingchemiluminescence technique on ADVIA Centaur® XP. Serum TSH levels were also analyzed twice daily; in the morning (0800 to 0900 hours) and afternoon (1400 to 1600 hours). Data was analyzed using SPSS version 24. Frequency and percentages were calculated for qualitative variables like gender and pre-analytical variables. Test of significance Mann-Whitney U-test was applied and p-value <0.05 was taken as significant. Results: Mean age of subjects was 23 ± 3.4 years. Change in circadian rhythm was observed in 17 (28%) males and 14 (36%) females. Statistically significant association was found between morning and evening TSH levels, while no change was observed in TSH level by early and late centrifugation of samples. Conclusion: TSH levels vary significantly between blood samples collected at different timings of the day from the same person. TSH is resistant to degradation, immunologically stable, and reasonably insensitive to potential problems associated with routine specimen handling, when measured by immunoassay technique. Therefore, it is helpful in large epidemiological studies and small size laboratory, which require long transportation time and storage.

scholarly journals Assessment of Finger Proprioception and Lateral Pinch Strength in Amateur and Professional Guitarists

2020 ◽  
Vol 06 (04) ◽  
pp. 6-11
Author(s):  
Hannah D’souza ◽  
Keyword(s):  
Demographic Data ◽  
Movement Patterns ◽  
Cross Sectional Study ◽  
Pinch Strength ◽  
P Value ◽  
Sectional Study ◽  
Cross Sectional ◽  
Left Hand ◽  
Good Strength ◽  
The Right

Background: Guitarists use complex and different movement patterns in both hands simultaneously. Applying pressure on the strings and strumming both require good strength whereas playing the melody on the fret-board demands good proprioception. There is a need to find out if guitarists perform functionally well with respect to pinch strength and proprioception which are prerequisites for playing the guitar. Therefore, the aim of the study is to assess and compare finger proprioception and pinch strength in amateur and professional guitarists. Methodology: A cross sectional study was conducted on 50 amateur and 50 professional guitarists from Mumbai. A self-made questionnaire including their demographic data was asked to be filled. Proprioception was measured using the pinch aperture proprioception device and lateral pinch strength was measured using the Jamar® Hydraulic Pinch Gauge. The average of 3 trials was taken for finger proprioception and lateral pinch strength. The data obtained was then taken for further analysis. Result: Professional guitarists had better finger proprioception (p value = 0.0001 for both right & left hands) and lateral pinch strength (p value =0.0159, 0.0001 for the right & left hand respectively) than amateur guitarists. Also, the left hand had better finger proprioception (p value <0.0001, 0.0059 for amateur & professional guitarists respectively) and right hand had better lateral pinch strength (p value=0.0001 for both professional and amateur guitarists) in both professional and amateur guitarists. Conclusion: Professional guitarists had significantly better finger Proprioception and lateral pinch strength as compared to the amateur guitarists.

scholarly journals CELIAC DISEASE

2015 ◽  
Vol 22 (01) ◽  
pp. 072-075
Author(s):  
Sana Zulfiqar ◽  
Amin Fahim ◽  
Aneela Qureshi ◽  
Sadia Adnan ◽  
Shomail Saeed Siddiqui ◽  
...  
Keyword(s):  
Celiac Disease ◽  
Histopathological Examination ◽  
Duodenal Mucosa ◽  
Cross Sectional Study ◽  
University Hospital ◽  
P Value ◽  
Cross Sectional ◽  
Marsh Type ◽  
History Of ◽  
And Gender

Objective: To find out the Modified Marsh type of celiac disease (CD)patients on histopathological examination of duodenal (D2) biopsies and to correlate it withtissue transglutaminase IgA levels. Study Design: Cross sectional study. Place of Study:Histopathology laboratory (Department of Pathology), Isra University Hospital and AsianInstitute of Medical Sciences (AIMS), Hyderabad. Duration of Study: July 2013 to December2013. Materials and Methods: 96 patients with a history of malabsorption or atypical symptomswith clinical suspicion of CD were subjected to endoscopy. Endoscopic duodenal (D2) biopsieswere taken regardless of age and gender. D2 biopsies were processed for histopathologicalexamination under light microscopy. Results: Out of 96 patients, 45 (46.9%) patients hadmoderate type of lamina propria inflammation along with highly significant p-value (0.0001).CDtype 3a was observed in 34 patients (35.4%). In this study the comparison of serological level oftissue Transglutaminase IgA (tTGA) and histological severity revealed significant correlation. AllModified Marsh types of CD with tTGA level seen in our study were highly significant (p-value0.001). Conclusion: In this study strong correlation was observed between the serologicaltTGA level and histological findings by Modified Marsh classification along with lamina propriainflammation of duodenal mucosa in CD patients.

scholarly journals Penentuan Jenis Kelamin berdasarkan Indeks Kaninus (Sex Determination Based on Canine Index)

MEDULA ◽  
2020 ◽  
Vol 7 (2) ◽  
Author(s):  
Raja Al Fath Widya Iswara
Keyword(s):  
Sex Determination ◽  
Cross Sectional Study ◽  
Forensic Identification ◽  
P Value ◽  
Test Results ◽  
Research Subjects ◽  
Cross Sectional ◽  
Lower Jaw ◽  
Spearman Correlation Test ◽  
The Right

Background: Identification is an effort made to determine a person's identity. One of the important things in identification is sex determination. Teeth are the hardest part of the human body and are protected in the oral cavity so they have a major role in forensic identification. Canine is the longest teeth and oftentimes used in identification. Purpose: To  determine the sex based on the canine index. Methods: An observational analytic cross-sectional study design with 250 research subjects of Halu Oleo University Medical Faculty students from October to December 2018, ages 18-25 years, who met the inclusion criteria, male (n = 125) and female (n = 125). Canine index by calculating the ratio of mesiodistal width (a measure of the width of canines measured from the two widest ends) divided by the distance between canines in four regions namely upper right jaw, upper left jaw, lower right jaw and upper left jaw. Result: Spearman correlation test results of canine index to sex, namely the upper right jaw value of p = 0.124, the upper left jaw value of p = 0.117, the right and right lower jaw with the p value = 0,000. Conclusion: The lower jaw canine index can be used in sex determination, where male have greater lower jaw canine index than female.Keywords: identification, canine index, sex ABSTRAKLatar Belakang: Identifikasi merupakan upaya yang dilakukan untuk menentukan identitas seseorang. Salah satu hal penting dalam identifikasi adalah penentuan jenis kelamin. Gigi merupakan bagian paling keras dari tubuh manusia dan terlindung di dalam rongga mulut sehingga mempunyai peran besar dalam identifikasi forensik. Kaninus/gigi taring merupakan gigi yang paling panjang diantara semua gigi dan sering digunakan dalam identifikasi. Penelitian ini bertujuan untuk mengetahui penentuan jenis kelamin berdasarkan indeks kaninus. Metode: Penelitian analitik observasional rancangan cross sectional dengan 250 subyek penelitian mahasiswa Fakultas Kedokteran Universitas Halu Oleo Periode Oktober-Desember 2018, usia 18-25 tahun, yang memenuhi kriteria inklusi, laki-laki (n=125) dan perempuan (n=125). Indeks kaninus dengan menghitung rasio lebar mesiodistal (ukuran lebar dari gigi taring yang diukur daripada kedua ujung yang terlebar) dibagi jarak antar kaninus pada empat regio yaitu rahang atas kanan, rahang atas kiri, rahang bawah kanan dan rahang bawah kiri. Hasil: Hasil uji korelasi Spearman indeks kaninus terhadap jenis kelamin yaitu pada rahang kanan atas nilai p=0,124, rahang kiri atas nilai p=0,117, rahang kanan dan kiri bawah dengan nilai p=0,000. Simpulan:  Indeks kaninus rahang bawah dapat digunakan dalam penentuan jenis kelamin, laki-laki mempunyai indeks kaninus rahang bawah lebih besar dibanding perempuan.Kata kunci: identifikasi, indeks kaninus, jenis kelamin

scholarly journals Priority Setting of Ventilators in the COVID-19 Pandemic from the public’s perspective

2020 ◽  
Author(s):  
Fariba Asghari ◽  
Alireza Parsapour ◽  
Ehsan Shamsi Gooshki
Keyword(s):  
Health Care Providers ◽  
Healthcare Workers ◽  
Public Discourse ◽  
Cross Sectional Study ◽  
P Value ◽  
Care Providers ◽  
Cross Sectional ◽  
Health Crisis ◽  
The Right ◽  
Periodic Evaluation

AbstractBackgroundVentilator allocation plan for public health crisis should be developed through recognizing the values of society and engaging the general public. This study was conducted to assess the Iranian citizens’ attitude about a number of principles and criteria for allocation of ventilators in current COVID-19 epidemic.Materials and MethodsAn electronic self-administered questionnaire was publicly distributed through social networks of Telegram and WhatsApp to perform this cross-sectional study. The questionnaire consisted of 11 statements about the selection and prioritization of patients for the use of a ventilator.Results1262 persons, including 767 citizens and 495 health care providers participated in this study. More than 95% of participants agreed upon the necessity to avoid discrimination and avoid prioritization according to patients’ gender, economic and political status. While 40.9% of citizens and 49.6% of healthcare workers believed that a ventilator can be disconnected from a patient with a poor prognosis to help a patient who has a better prognosis (P-value=0.13), 34.3% of people and 29.6% of healthcare workers believed that the earlier admitted patients have the right to receive the device even if the likeliness of his/her survival is less than the next patient (P-value=0.009).ConclusionsThis study showed that people accept maximizing health benefits as a measure of ventilator allocation in the pandemic of COVID-19. At the same time, periodic evaluation of patients and disconnecting the device from a patient that no longer benefits from ICU services requires its scientific and ethical basis to be brought in public discourse.

scholarly journals Patients’ attitude and factors influencing the acceptance of medical students’ participation in pelvic examination

2022 ◽  
Vol 7 (1) ◽  
pp. 87-97
Author(s):  
Nisakorn Deesaen ◽  
Kongpop Sutantikorn ◽  
Punyanuch Phonngoenchai ◽  
Sakchai Chaiyamahapruk ◽  
Patcharada Amatyakul
Keyword(s):  
Medical Student ◽  
Medical Students ◽  
Clinical Skills ◽  
Cross Sectional Study ◽  
University Hospital ◽  
P Value ◽  
Pelvic Examination ◽  
Cross Sectional ◽  
Pelvic Examinations ◽  
Matters Of Concern

Introduction: Pelvic examination of patients in the department of obstetrics and gynaecology (Ob-Gyn) is an important skill for medical students. Because it involves a physical assessment of the patients' genitalia, patients may refuse medical students to participate in the examination, affecting the medical students' clinical skills. Methods: This cross-sectional study was conducted at Naresuan University Hospital to determine the factors that influence the acceptance of medical student participation in the pelvic examinations. A total of 198 out-patients from the Ob-Gyn department were included. A Likert scale questionnaire was designed which featured topics on patients’ attitudes and circumstances related to medical student involvement in gynaecological procedures. Results: The majority of outpatients (71.7%) accepted the participation of medical students in pelvic examinations. Patients with prior experiences in physical and pelvic examination by medical students had a significant impact on the patients' acceptance (P-value<0.001). The patients’ impressions had an influence on the decision to accept students in pelvic exam participation. Approximately 40% of patients were concerned about the breach of confidentiality. However, most patients strongly agreed that allowing medical students to perform pelvic examination would benefit their medical education. Conclusion: Most of the participants permitted medical students to participate in pelvic examinations and preferred that the medical instructor be the one to request permission. The patients’ impressions of medical students were crucial factors that significantly influence their decision whether to allow or deny them to participate in the procedure. Disclosure of confidentiality was found to be matters of concern to most patients.

Computed tomography assessment of the ethmoid roof based on Keros classification in Iraqi patients undergoing functional endoscopic sinus surgery

2021 ◽  
Vol 4 (2) ◽  
pp. 365-370
Author(s):  
Baseem Natheer Abdulhadi ◽  
Ali Ibrahim Shyaa ◽  
Laith ALTamimi
Keyword(s):  
Endoscopic Sinus Surgery ◽  
Cross Sectional Study ◽  
Common Type ◽  
Functional Endoscopic Sinus Surgery ◽  
Sinus Surgery ◽  
P Value ◽  
Type I ◽  
Cross Sectional ◽  
And Gender ◽  
The Right

Background: Among the most popular methods employed to classify the depth of the olfactory fossa is Keros classification. This study aims to assess Keros classification of the ethmoid roof, any possible association between Keros types and gender, and the incidence of asymmetry between right and left sides among Iraqi patients.  Methods: A retrospective cross-sectional study was conducted at Al-Shaheed Gazi Al-Hariri Teaching Hospital, Medical City, Baghdad, Iraq. The archived reports and the CT scans images (nose and paranasal sinuses) of 126 patients who have undergone functional endoscopic sinus surgery between January 2019 and January 2020 were reviewed. Univariate and bivariate statistical analysis was performed using SPSS version 24. The statistically significant was considered at less than 0.05. Results: More than half of patients were females (54.0%) with a mean age of 31.52 ± 11.38 (SD) years (range: 10-57 years). Among the total patients, the mean depth of olfactory fossa (OF) was 3.58 ± 0.02 mm. Results showed that Keros type I was the most common type (71.0%), followed by type II (27.4%) and type III (1.6%) respectively. The difference in the olfactory fossa depth between the right and left sides was ≥ 1 mm in 16 (12.7%) patients and < 1 mm in 110 (87.3%) patients. Moreover, there was no significant relation between symmetry/asymmetry and gender ( p-value > 0.05). Conclusion: Keros type I was the most common type, which carries the lowest risk of inadvertent intracranial injury during endoscopic sinus surgery; besides the relatively low percentage of asymmetry in the depth of the two olfactory fossae among patients, surgeons should always be cautious during surgery to avoid iatrogenic injury concerning the thin lateral lamella of the cribriform plate.

scholarly journals Spontaneous Bacterial Empyema in Cirrhotic patients with Hepatic hydrothorax.

2020 ◽  
Vol 27 (01) ◽  
pp. 115-119
Author(s):  
Ehsan Rahim Memon ◽  
Prem Kumar Maheshwari ◽  
Shabana Lakho ◽  
Huma Mehmood
Keyword(s):  
Cell Count ◽  
Cross Sectional Study ◽  
University Hospital ◽  
P Value ◽  
Hepatic Hydrothorax ◽  
Cross Sectional ◽  
Class B ◽  
Cirrhotic Patients ◽  
One Year ◽  
Spontaneous Bacterial Empyema

Objectives: To determine the frequency of spontaneous bacterial empyema in cirrhotic patients with hepatic hydrothorax. Study Design: Descriptive cross sectional study. Setting: Conducted in gastroenterology unit at Isra University Hospital, Hyderabad. Periods: One year from April 2016 to March 2017. Material & Methods: Sample of 174 patients of Hepatic Hydrothorax was taken. Patients were of both gender and age ≥ 18 years, having diagnosed cirrhosis since last 5 years and currently having child class B & C severity were included. Hepatic hydrothorax was confirmed on ultrasound chest. After aseptic measures 50ml of pleural fluid was aspirated and sent to Isra University Hospital laboratory following the ultrasound guidelines. Spontaneous bacterial empyema was assessed as “polymorph nuclear cell count” more than 500 cells/mm3 or +ve culture with PMN cell count more than 250 cells/mm3 without parapneumonic effusion. All the data was recorded in the proforma. Results: The mean ± SD age of patients was 53.52 ± 5.52 years. Males were 60.92% while 39.08% were females. The frequency of spontaneous bacterial empyema was about 14.9%. Frequency of spontaneous bacterial empyema was little more in male gender than females (p value = 0.391), while it was significantly increased with increasing age as most common in age group of 61-65 years (p-value = 0.017). Conclusion: It was concluded that spontaneous bacterial empyema in cirrhosis patients was 14.9%.

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