scholarly journals Management of Vaccination Failure in a Case of HIV -HBV Co-infection: A Case Report

2014 ◽  
Vol 2 (2) ◽  
pp. 68-70
Author(s):  
Andre Small ◽  
Hilary Schroeder ◽  
Raghu Maramraj ◽  
Marianinha Joanes
Keyword(s):  
African American ◽  
Case Report ◽  
Immune System ◽  
Hiv Infection ◽  
African American Female ◽  
Cell Dysfunction ◽  
The Past ◽  
Immune System Dysfunction ◽  
B Virus ◽  
Chronic Hiv Infection

Background: A 60-year-old African American female patient, with chronic HIV infection since 1999, presented with markers of acute hepatities B virus (HBV) infection for the past 15 months. The patient was previously vaccinated for HBV. Immunoglobulin dysfunction was hypothesized, but electrophoresis yielded no conclusive result. Results: Investigation suggests that the patient is a non-responder: someone who fails to sero-convert to standard vaccinations. This condition can be linked to B-cell dysfunction due to chronic HIV infection. Conclusion: It is suggested that non-responders may require a 6-dose regimen to achieve sero-conversion for vaccination. Prevention of co-infection should be the mainstay of treatment, which is achieved by vaccination. However, immune system dysfunction can lead to complications.

scholarly journals A Giant Cell Fibroma and Focal Fibrous Hyperplasia in a Young Child: A Case Report

2012 ◽  
Vol 2012 ◽  
pp. 1-5 ◽  
Author(s):  
Rodney J. Vergotine
Keyword(s):  
African American ◽  
Case Report ◽  
Young Child ◽  
Giant Cell ◽  
Clinical Impact ◽  
The Other ◽  
African American Female ◽  
Distinct Entity ◽  
Anterior Maxilla ◽  
Attached Gingiva

A case of two fibrotic lesions of the oral mucosa in a 17-month-old African-American female is reported. Both lesions occurred on the anterior maxilla, one lesion pedunculated on the buccal attached gingiva and the other lesion sessile on the palate. Histological examination characterized the buccal lesion as focal fibrous hyperplasia (FFH) and the palatal lesion as a giant cell fibroma (GCF). A case is made for continuing the consideration of GCF as a histologically distinct entity from FFH but that no difference in clinical impact between the two lesions exists.

A rare case report of hemochromatosis in an African-American female

2000 ◽  
Vol 95 (9) ◽  
pp. 2580-2580 ◽  
Author(s):  
Hitender Jain ◽  
M.A. Albornoz ◽  
J. Collazo ◽  
J.M. Greenblatt ◽  
J.M. Draganescu ◽  
...  
Keyword(s):  
African American ◽  
Case Report ◽  
Rare Case ◽  
African American Female ◽  
Rare Case Report

scholarly journals Free Light Chains as a Novel Diagnostic Biomarker of Immune System Abnormalities in Multiple Sclerosis and HIV Infection

2019 ◽  
Vol 2019 ◽  
pp. 1-7
Author(s):  
Monika Gudowska-Sawczuk ◽  
Barbara Mroczko
Keyword(s):  
Multiple Sclerosis ◽  
Immune System ◽  
Hiv Infection ◽  
Light Chains ◽  
Laboratory Diagnostics ◽  
Elevated Concentration ◽  
Free Light Chains ◽  
Heavy Chains ◽  
Immune System Dysfunction ◽  
Pubmed Database

Introduction. Immunoglobulins are molecules composed of two heavy and two light chains. Light chains are produced by B lymphocytes during the synthesis of immunoglobulins, and physiologically light chains are generally produced in excess compared to heavy chains. Light chains that are not combined to heavy chains in a whole immunoglobulin are called free light chains (FLCs). B-cell abnormalities are associated with disorders leading to an abnormal concentration of free light chains. In this study, we focus on the described changes of serum and cerebrospinal fluid concentration of free light chains in inflammatory disorders: multiple sclerosis, HIV infection, and HIV-associated lymphomas. Methods. We performed broad research of the literature pertaining to our investigation via the MEDLINE/PubMed database. Results. It has been proven that FLC determination can provide rapid information about intrathecal inflammation in patients with multiple sclerosis. Moreover, literature data suggest that free light chain determination is the most interesting alternative for oligoclonal band analysis. In the present review, we also described that HIV-related immune system dysfunction is associated with an elevated concentration of serum-free light chains. Additionally, FLCs are potentially a strong and sensitive predictor of the risk of developing HIV-associated lymphomas. Conclusion. Based on these published findings, we suggest that free light chains have high diagnostic sensitivity, which probably enables application in laboratory diagnostics.

scholarly journals Case Report: A case report of Moyamoya disease in a 36 year old African American woman

F1000Research ◽  
2014 ◽  
Vol 3 ◽  
pp. 297 ◽  
Author(s):  
Rohit Kumar Gudepu ◽  
Mohtashim A. Qureshi ◽  
Ihtesham A. Qureshi ◽  
Lakshman Rao
Keyword(s):  
African American ◽  
Case Report ◽  
Blood Vessels ◽  
Medical Therapy ◽  
Moyamoya Disease ◽  
African American Woman ◽  
American Woman ◽  
African American Female ◽  
Ct Angiogram ◽  
The Brain

Moyamoya is a rare idiopathic progressive vaso-occlusive disease characterized by irreversible condition of main blood vessels to the brain as they enter into the skull. We present a case of 36 year old African American female presenting to the Out Patient Clinic with headache which were on and off for 4-6 months and did not relieve on routine medical therapy. It was associated with weakness on right side for last few days. The patient was investigated with CT Angiogram, diagnosed as Moyamoya disease and operated. She has been followed up for the last 5 years and the patient has not complained of any headaches or focal neurological symptoms.

Hyperpigmented nodular rash in a 61-year-old African American female

2022 ◽  
pp. 42-44
Author(s):  
Danielle C. Ware
Keyword(s):  
African American ◽  
Family Health ◽  
Aneurysm Rupture ◽  
African American Female ◽  
The Past ◽  
Below The Knee ◽  
Back Face ◽  
History Of ◽  
Skin Nodules

A 61-year-old African American female presents to an outpatient family health center with a hyperpigmented nodular rash of 2 months’ duration. The rash first appeared on her abdomen before spreading across her upper arms, lower leg, back, face and scalp. She has a history of controlled type 2 diabetes mellitus, cerebral aneurysm rupture, Sjögren’s syndrome, asthma and a left below-the-knee amputation due to osteomyelitis. She smokes cigarettes but does not use alcohol or illicit substances. She has also noticed a dry cough with mild dyspnea on exertion over the past 6 months. On physical exam, hyperpigmented nodules are palpable in both the intradermal and subcutaneous layers of the skin. Nodules are firm, mobile and nontender. Alopecia is noted where scalp nodules are present. Her lungs exhibit diminished air movement throughout, with scattered, end-expiratory wheezing.

scholarly journals African American female with renal failure presenting with skin lesions: a case report

Cases Journal ◽  
2009 ◽  
Vol 2 (1) ◽  
pp. 8701 ◽  
Author(s):  
Sajitha MF Rahman ◽  
Nejla Israel ◽  
Tsveti Markova
Keyword(s):  
Renal Failure ◽  
African American ◽  
Case Report ◽  
Skin Lesions ◽  
African American Female

scholarly journals Hepatotoxicity due to Clindamycin in Combination with Acetaminophen in a 62-Year-Old African American Female: A Case Report and Review of the Literature

2016 ◽  
Vol 2016 ◽  
pp. 1-5 ◽  
Author(s):  
Jerome Okudo ◽  
Nwabundo Anusim
Keyword(s):  
African American ◽  
Case Report ◽  
Side Effects ◽  
Broad Spectrum ◽  
Tooth Extraction ◽  
African American Female ◽  
Review Of The Literature ◽  
Dental Clinic ◽  
Metallic Taste ◽  
Liver Transaminases

Clindamycin is a bacteriostatic lincosamide antibiotic with a broad spectrum. Side effects include nausea, vomiting, diarrhea, and metallic taste; however, hepatotoxicity is rare. The incidence is unknown. It is characterized by increases in aspartate and alanine transaminases. There may be no symptoms and the treatment is to stop the administration of clindamycin. We have described a 62-year-old African American female medicated with acetaminophen and clindamycin who had initially presented to the dental clinic for the evaluation of gum pain following tooth extraction. She had significantly increased levels of liver transaminases, which trended downwards on quitting the medication.

scholarly journals Catatonia and Schizophrenia: A Case Report

2017 ◽  
Vol 2 (1) ◽  
Keyword(s):  
Case Report ◽  
Psychiatric Care ◽  
Drug Withdrawal ◽  
Past History ◽  
Paranoid Schizophrenia ◽  
African American Female ◽  
The Past ◽  
History Of ◽  
Catatonic Schizophrenia ◽  
Ward Patient

This case is of a 47 year old African American female diagnosed with catatonic schizophrenia and paranoid schizophrenia which has deteriorated over the past two weeks. The patient recently attacked her father, has been mute and has also been throwing herself onto the floor expressing disorganized thoughts, poorly taking care of self and insomnia. The patient was first admitted for psychiatric care at the age of 20 and has a past history of DVT of lower extremities, hypertension, obesity and anemia. No signs of intoxication or drug withdrawal were observed. Patient had been on Haldol decanoate 300 mg IM. After admission in ward patient was continued on Haldol decanoate, Depakote and Lorazepam. Patient responded well to treatment and a certain level of independence wasachieved

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