scholarly journals The HUPO Human Proteome Project (HPP), a Global Health Research Collaboration

2012 ◽  
Vol 1 (1) ◽  
Author(s):  
Gilbert S. Omenn
Keyword(s):  
Research Collaboration ◽  
Genome Project ◽  
Human Proteome ◽  
Global Health Research ◽  
Preventive Interventions ◽  
World Congress ◽  
Research Teams ◽  
Human Proteome Project ◽  
Biological Foundation ◽  
Sydney Australia

The global Human Proteome Project (HPP) was announced by the Human Proteome Organization (HUPO) at the 2010 World Congress of Proteomics in Sydney, Australia, and launched at the 2011 World Congress of Proteomics in Geneva, Switzerland, with analogies to the highly successful Human Genome Project. Extensive progress was reported at the September 2012 World Congress in Boston, USA. The HPP is designed to map the entire human proteome using available and emerging technologies.The HPP aims to create a molecular and biological foundation for improving health globally through better understanding of disease processes, more accurate diagnoses, and targets for more effective therapies and preventive interventions against many diseases. There are opportunities for individual investigators everywhere to access advanced datasets and to join HPP research teams.

scholarly journals Human Proteome Project and Current Bioinformatics Status in Disease Diagnosis and Treatment

2018 ◽  
pp. 23-40
Author(s):  
Pervez Anwar ◽  
Ayesha Javed ◽  
Izba Amjad ◽  
Iqra Arif ◽  
Attiqa Sadiqa ◽  
...  
Keyword(s):  
Disease Diagnosis ◽  
Extensive Study ◽  
Genome Project ◽  
Protein Profiling ◽  
Human Proteome ◽  
Post Translational Modification ◽  
Human Organ ◽  
Proteomic Data ◽  
Bioinformatics Tools ◽  
Human Proteome Project

Human proteome project was revolutionized about 40 years ago with purpose of summarizing whole proteomic data at one place. It was launched after human genome project to map and observe all proteins. The goal related proteomic study is to draft the entire human proteome in disease diagnosis by using bioinformatics tools. Pillars of human proteome project provide different databases related to proteins at transcriptional and translational level. Human proteome organization(HUPO) published biology disease HUPO whose aim is to measure protein and proteome by life and processes related to human diseases. Different human organ like plasma, liver, brain and diabetic base project are used to characterize human disease and health. Major data resources accumulated in databases like peptides Atlas, GPMDB and neXtProt for proteins. Matrices of human proteome project identify and characterize the protein products as Post translational modification (PTM), splice various isoforms from 20,300 proteins. Matrices related to different years make proteomes counterpart by magnify the research biomedical community with high output of instruments and specimen pre-analytical protocols. CALIPHO multidisciplinary group provides information about protein complexities, interactions, function and structure complexities after Uniport and Swissprot. Different bioinformatics tools are used for structural and functional annotations of protein, disease diagnosis and mutations due to protein. Extensive study of human proteome project has been proved helpful in disease treatment at translational and post- translational levels. In future, human proteome project along with bioinformatics will include protein profiling, biomarkers, Mass spectrophotometer technique and cross analysis of different proteome projects.

scholarly journals Is a gene-centric human proteome project the best way for proteomics to serve biology?

PROTEOMICS ◽  
2010 ◽  
Vol 10 (17) ◽  
pp. 3067-3072 ◽  
Author(s):  
Thierry Rabilloud ◽  
Denis Hochstrasser ◽  
Richard J. Simpson
Keyword(s):  
Human Proteome ◽  
Human Proteome Project

Progress Identifying and Analyzing the Human Proteome: 2021 Metrics from the HUPO Human Proteome Project

2021 ◽  
Author(s):  
Gilbert S. Omenn ◽  
Lydie Lane ◽  
Christopher M. Overall ◽  
Young-Ki Paik ◽  
Ileana M. Cristea ◽  
...  
Keyword(s):  
Human Proteome ◽  
Human Proteome Project

scholarly journals Progress on the HUPO Draft Human Proteome: 2017 Metrics of the Human Proteome Project

2017 ◽  
Vol 16 (12) ◽  
pp. 4281-4287 ◽  
Author(s):  
Gilbert S. Omenn ◽  
Lydie Lane ◽  
Emma K. Lundberg ◽  
Christopher M. Overall ◽  
Eric W. Deutsch
Keyword(s):  
Human Proteome ◽  
Human Proteome Project

Human Proteome Project and Human Pluripotent Stem Cells: Odd Bedfellows or a Perfect Match?

2020 ◽  
Vol 19 (12) ◽  
pp. 4747-4753
Author(s):  
Mehdi Alikhani ◽  
Razieh Karamzadeh ◽  
Pardis Rahimi ◽  
Samane Adib ◽  
Hossein Baharvand ◽  
...  
Keyword(s):  
Stem Cells ◽  
Pluripotent Stem Cells ◽  
Perfect Match ◽  
Human Pluripotent Stem Cells ◽  
Human Proteome ◽  
Human Proteome Project

scholarly journals Positional proteomics in the era of the human proteome project on the doorstep of precision medicine

Biochimie ◽  
2016 ◽  
Vol 122 ◽  
pp. 110-118 ◽  
Author(s):  
Ulrich Eckhard ◽  
Giada Marino ◽  
Georgina S. Butler ◽  
Christopher M. Overall
Keyword(s):  
Precision Medicine ◽  
Human Proteome ◽  
Human Proteome Project
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