scholarly journals Tranexamic Acid in the Treatment of Hip Fractures: A Clinical Review

2019 ◽  
Author(s):  
Nathan M. Krebs ◽  
Michael J. VanWagner ◽  
Tiffany Marchewka ◽  
Usama Faraj ◽  
Christopher R. Vitale
Keyword(s):  
Tranexamic Acid ◽  
Clinical Review ◽  
Hip Fractures

Tranexamic acid: a clinical review

2015 ◽  
Vol 47 (4) ◽  
pp. 339-350 ◽  
Author(s):  
William Chuk Kit Ng ◽  
Angela Jerath ◽  
Marcin Wasowicz
Keyword(s):  
Tranexamic Acid ◽  
Clinical Review

scholarly journals A Single Dose Versus Two Doses of Tranexamic Acid for Extracapsular Hip Fractures

Cureus ◽  
2022 ◽  
Author(s):  
Max Jiganti ◽  
Olivia Pipitone ◽  
Justin Than ◽  
Richard Stanley ◽  
Angela Passanise ◽  
...  
Keyword(s):  
Single Dose ◽  
Tranexamic Acid ◽  
Hip Fractures

Does perioperative use of tranexamic acid in hip fracture patients increase the risk of venous thromboembolism and reduce the need for postoperative transfusions?

2020 ◽  
Vol 30 (12) ◽  
pp. 378-382
Author(s):  
James Geddes ◽  
Greg McConaghie
Keyword(s):  
Venous Thromboembolism ◽  
Hip Fracture ◽  
Blood Loss ◽  
Tranexamic Acid ◽  
Hip Fractures ◽  
Hip Fracture Surgery ◽  
Postoperative Blood Transfusion ◽  
Increased Risk ◽  
Fracture Surgery ◽  
Postoperative Haemoglobin

Perioperative tranexamic acid use is a popular choice among many surgeons for reducing surgical blood loss and its sequelae. While there is evidence in the literature that tranexamic acid use is effective in reducing blood loss in surgery for patients with hip fractures, there is less information on whether it leads to thromboembolic complications. We undertook a retrospective study in patients with hip fractures at two local hospitals to investigate if there was an increased risk of venous thromboembolism in patients who received tranexamic acid, and whether it reduced perioperative blood loss and the need for transfusion. We found that tranexamic acid used in patients undergoing hip fracture surgery reduced the drop in postoperative haemoglobin and the need for postoperative blood transfusion but was not associated with an increased risk of venous thromboembolism.

scholarly journals Intravenous Tranexamic Acid Decreases Blood Transfusions and Blood Loss for Patients with Surgically Treated Hip Fractures

2021 ◽  
Vol 12 ◽  
pp. 215145932110636
Author(s):  
Phuong Anh N Huynh ◽  
Megan Miller ◽  
Ryan Will
Keyword(s):  
Blood Loss ◽  
Tranexamic Acid ◽  
Risk Reduction ◽  
Hip Fractures ◽  
Absolute Risk ◽  
Blood Transfusions ◽  
Total Blood ◽  
Allogenic Blood ◽  
Operative Care ◽  
Decrease Blood Loss

Introduction Tranexamic acid can decrease blood loss related to surgery and trauma. The primary objective of this study is to examine if the use of a single dose of peri-operative TXA significantly decreases the rate of allogenic blood transfusions in the setting of operative care of hip fractures. Secondary objectives included examining if total blood loss was decreased by TXA in operative hip fractures as well as examining the safety of TXA by measuring the rates venous thromboembolism (VTE). Methods Retrospective chart review of 505 patients who were operatively treated for hip fractures at a single facility was performed. In a non-randomized fashion, 307 patients received TXA and 198 patients did not. Patients received 1 gram of TXA prior to incision. Blood transfusion was the primary end point. Blood loss was calculated using the hemoglobin balance method. Chart was reviewed for VTE events during hospitalization. Results 505 patients were analyzed. The use of single perioperative dose of TXA in the surgical management of hip fracture resulted in absolute risk reduction of transfusion of 7.7% and relative risk reduction of transfusion by 29%. This was statistically significant with P =.04. Patients who received TXA on average lost 235 ml less blood compared to those who did not receive TXA ( P <.0001). No increase in VTE events were found in either group during hospitalization. Conclusion This study supports the use of TXA is decrease blood loss and transfusion rates in patients with hip fractures. TXA can be used routinely to decrease complications in this usually fragile population.

scholarly journals Expanded use of tranexamic acid is safe and decreases transfusion rates in patients with geriatric hip fractures

2021 ◽  
Vol 4 (4) ◽  
pp. e147
Author(s):  
Joseph B. Kahan ◽  
Jensa Morris ◽  
Don Li ◽  
Jay Moran ◽  
Mary I. O’Connor
Keyword(s):  
Tranexamic Acid ◽  
Hip Fractures

Hip Fractures Rose at Start of Antihypertensives

2012 ◽  
Vol 45 (18) ◽  
pp. 2
Author(s):  
PATRICE WENDLING
Keyword(s):  
Hip Fractures
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