scholarly journals Real world management of esophageal ulcers : analysis of their presentation, etiology, and outcomes

2021 ◽  
Vol 84 (3) ◽  
Author(s):  
D.L. Cohen ◽  
A Bermont ◽  
V Richter ◽  
H Shirin

Background and study aims : Esophageal ulcers are a rare cause of upper gastrointestinal morbidity and may be due to different etiologies. We sought to systematically evaluate patients with esophageal ulcers and describe their presentations, endoscopic findings, etiologies, treatments, and outcomes. Patients and methods : Patients diagnosed with esophageal ulcers over an 11-year period were retrospectively identified from our institution’s electronic medical records. Results : We identified 100 patients with esophageal ulcers (0.49% of patients undergoing upper endoscopy). Half of them presented due to gastrointestinal bleeding and three-quarters were admitted to the hospital. The majority were in the lower esophagus. Twenty-two unique etiologies, including multiple iatrogenic causes, were diagnosed in 91 of the cases. The most common etiology was gastroesophageal reflux disease (57%), followed by non-steroidal anti-inflammatory drug use (7%), malignancies (3%), vomiting (3%), caustic ingestion (2%), pill esophagitis (2%) and radiation (2%). Many etiologies showed a predilection for specific segments of the esophagus. Nine ulcers required endoscopic intervention and all were treated successfully. Repeat endoscopies were performed 5 times for diagnostic or “second look” reasons, none of which changed the patients’ diagnosis or treatment. No patients required surgery or stricture dilation. One patient’s ulcer was complicated by perforation and he subsequently died. Four other patients died from non-ulcer related causes. Conclusions : While the majority of ulcers were due to gastro-esophageal reflux disease, 22 different etiologies were identified. Many were due to medication or iatrogenic causes. Repeat endoscopy did not appear to be helpful. While the incidence was low, they were frequently associated with significant morbidity.

2016 ◽  
Vol 5 (1) ◽  
Author(s):  
Fadhil Alfino Azmi ◽  
Saptino Miro ◽  
Detty Iryani

AbstrakPerdarahan saluran cerna bagian atas adalah kehilangan darah dalam lumen saluran cerna yang bermula dari esofagus sampai duodenum. Manifestasi kinis berupa hematemesis (muntah darah) dan atau melena (tinja hitam). Kasus ini masih banyak dilaporkan dari berbagai rumah sakit. Etiologi yang sering dilaporkan adalah varises esofagus, ulkus peptikum, gastritis erosif dan lain-lain. Tujuan penelitian ini adalah mengetahui frekuensi diagnosis esofagogastroduodenoskopi (EGD) pasien hematemesis dan atau melena di RSUP M Djamil Padang. Jenis penelitian yang digunakan adalah deskriptif retrospektif. Data diambil secara total sampling dari rekam medik pasien hematemesis dan atau melena yang dilakukan pemeriksaan EGD di Instalasi Diagnostik Terpadu (IDT) RSUP M Djamil Padang periode.Januari.2010.–.Desember.2013. Hasil penelitian menunjukkan 162 pasien kasus terbanyak adalah ulkus gaster (27,8%). Menurut jenis kelamin, pria lebih banyak dibanding wanita yaitu pria (64,8%) dan wanita (35,2%) rasio 1,8 : 1. Kelompok umur terbanyak adalah 51-60 tahun yaitu (20,0%). Lokasi lesi yang paling banyak ditemukan adalah gaster (48,8%).Kata kunci: esofagogastroduodenoskopi, perdarahan saluran cerna bagian atas, hematemesis, melena AbstractUpper gastrointestinal bleeding is a loss of blood in lumen of the gastrointestinal tract from esophagus to duodenum. Clinical manifestations are hematemesis (vomiting of blood) and/or melena (black stools). Many cases were widely reported from various hospitals. The most common etiology that often being reported are esophageal varices, peptic ulcer, erosive gastritis, etc. The objective of this study was to determine the frequency of esophagogastroduodenoscopy(EGD) findings in patients with hematemesis and/or melena in M Djamil Hospital Padang. The design of this research was retrospective descriptive. Data was taken from the result of patient's EGD examination(medical records) that having hematemesis and/or melena in Integrated Diagnostics Installation of M Djamil Hospital Padang from January 2010 to December 2013. The results showed that the highest cases of 162 patients were gastric ulcer (27.8%). According to gender, more men cases than women cases.  Men (64.8%) and women (35.2%) with ratio 1.8 : 1. Most cases occurred on 51-60 years old (20.0%). Location of lesions were most commonly found in gaster (48.8%).Keywords: esophagogastroduodenoscopy, upper gastrointestinal bleeding, hematemesis, melena


Author(s):  
Jhon F. Martinez-Paredes ◽  
Razan Alfakir ◽  
Jan L. Kasperbauer ◽  
Amy Rutt

Abstract Introduction Zenker diverticulum (ZD) usually affects adults after the 7th decade of life. Treatment for ZD is indicated for all symptomatic patients, but some patients prefer to defer surgical treatment until symptoms get worse and decrease their quality of life. Objective To evaluate the association of the preoperative symptoms in ZD patients with the size of the ZD. Methods A retrospective study design. Electronic medical records were used to identify patients diagnosed with ZD and treated over 11 years. Data collection included the chief complaints and symptoms, medical history, and findings on radiologic swallow evaluations of the patients. The diverticulum size was stratified into 3 groups: small (< 1 cm), moderate (1–3 cm), and large (> 3 cm). Results A total of 165 patients were enrolled and stratified by diverticulum size (48 small, 67 medium, and 50 large). Dysphagia, cough, and regurgitation were the most prevalent symptoms. Dysphonia was more frequent among patients with a small pouch. Logistic regression analysis showed that dysphagia and choking were associated with large and medium diverticulum size (p < 0.05). Additionally, dysphonia was significantly associated with the presence of a small-sized ZD (p < 0.04). Conclusion Upper gastrointestinal symptoms such as dysphagia and choking may be associated with a ZD > 1 cm and should always be evaluated. Additionally, the presence of dysphonia was found to be correlated with a ZD < 1 cm, suggesting that a prompt and appropriate fluoroscopic evaluation must be considered in those patients in whom no other clear cause of dysphonia is evident.


2014 ◽  
Author(s):  
C. McKenna ◽  
B. Gaines ◽  
C. Hatfield ◽  
S. Helman ◽  
L. Meyer ◽  
...  

Diabetes ◽  
2020 ◽  
Vol 69 (Supplement 1) ◽  
pp. 908-P
Author(s):  
SOSTENES MISTRO ◽  
THALITA V.O. AGUIAR ◽  
VANESSA V. CERQUEIRA ◽  
KELLE O. SILVA ◽  
JOSÉ A. LOUZADO ◽  
...  

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