scholarly journals Cytomegalovirus (CMV) Adrenalitis Leading to Adrenal Insufficiency in a Patient with AIDS, Disguised by Concomitant Corticosteroid Administration: A Case Report

2015 ◽  
pp. 1-4
Author(s):  
Sonakshi Sharma ◽  
Ian Holdaway
Keyword(s):  
Case Report ◽  
Adrenal Insufficiency ◽  
Corticosteroid Administration

scholarly journals Nitrofurantoin-Associated Acute Granulomatous Interstitial Nephritis

2021 ◽  
Vol 9 ◽  
pp. 232470962110016
Author(s):  
B. K. Anupama ◽  
Parth Sampat ◽  
Harvir S. Gambhir
Keyword(s):  
Acute Kidney Injury ◽  
Renal Function ◽  
Case Report ◽  
Interstitial Nephritis ◽  
Visual Hallucination ◽  
Kidney Injury ◽  
Corticosteroid Administration ◽  
Granulomatous Interstitial Nephritis ◽  
Rare Association ◽  
New Onset

We report the case of a 71-year-old female who was incidentally found to have nonoliguric acute kidney injury on a routine workup for new-onset visual hallucination. Further history revealed inadvertent usage of nitrofurantoin for 3 months for an anticipated urological procedure. Renal biopsy demonstrated acute granulomatous interstitial nephritis. The renal function significantly improved following discontinuation of nitrofurantoin and corticosteroid administration. We highlight a rare association of nitrofurantoin with acute granulomatous interstitial nephritis through this case report.

scholarly journals Primary adrenal insufficiency due to bilateral adrenal infarction in COVID-19: a case report

2021 ◽  
Author(s):  
Iza F R Machado ◽  
Isabel Q Menezes ◽  
Sabrina R Figueiredo ◽  
Fernando Morbeck Almeida Coelho ◽  
Debora R B Terrabuio ◽  
...  
Keyword(s):  
Case Report ◽  
Adrenal Insufficiency ◽  
Antiphospholipid Syndrome ◽  
Antiphospholipid Antibodies ◽  
Case Reports ◽  
Serum Cortisol ◽  
Primary Adrenal Insufficiency ◽  
Acute Adrenal Insufficiency ◽  
Adrenal Infarction ◽  
New Onset

Abstract Context Coronavirus disease 2019 (COVID-19) is a proinflammatory and prothrombotic condition, but its impact on adrenal function has not been adequately evaluated. Case report A 46-year-old woman presented with abdominal pain, hypotension, skin hyperpigmentation after COVID-19 infection. The patient had hyponatremia, serum cortisol <1.0 ug/dL, ACTH of 807 pg/mL and aldosterone <3 ng/dL. Computed tomography (CT) findings of adrenal enlargement with no parenchymal and minimal peripheral capsular enhancement after contrast were consistent with bilateral adrenal infarction. The patient had autoimmune hepatitis and positive antiphospholipid antibodies, but no previous thrombotic events. The patient was treated with intravenous hydrocortisone, followed by oral hydrocortisone and fludrocortisone. Discussion Among 115 articles, we identified nine articles, including case reports, of new-onset adrenal insufficiency and/or adrenal hemorrhage/infarction on CT in COVID-19. Adrenal insufficiency was hormonally diagnosed in five cases, but ACTH levels were measured in only three cases (high in one case and normal/low in other two cases). Bilateral adrenal non- or hemorrhagic infarction was identified in five reports (two had adrenal insufficiency, two had normal cortisol levels and one case had no data). Interestingly, the only case with well-characterized new-onset acute primary adrenal insufficiency after COVID-19 had a previous diagnosis of antiphospholipid syndrome. In our case, antiphospholipid syndrome diagnosis was established only after the adrenal infarction triggered by COVID-19. Conclusions Our findings support the association between bilateral adrenal infarction and antiphospholipid syndrome triggered by COVID-19. Therefore, patients with positive antiphospholipid antibodies should be closely monitored for symptoms or signs of acute adrenal insufficiency during COVID-19.

scholarly journals SINDROM TOLOSA HUNT DENGAN KETERLIBATAN SARAF OPTIKUS

2019 ◽  
Vol 37 (1) ◽  
Author(s):  
Astra Dea Simanungkalit ◽  
Maria Larasati Susyono ◽  
Vivien Puspitasari
Keyword(s):  
Visual Acuity ◽  
Case Report ◽  
Optic Nerve ◽  
Pain Relief ◽  
Clinical Syndrome ◽  
Orbital Apex ◽  
Corticosteroid Administration ◽  
Hunt Syndrome ◽  
Nerve Dysfunction ◽  
Optic Nerve Involvement

TOLOSA HUNT SYNDROME WITH OPTIC NERVE INVOLVEMENTABSTRACTTolosa Hunt syndrome (THS) is a very rare clinical syndrome, which is characterized by unilateral headaches accompanied by dysfunction and painful ophthalmic nerves. In some cases, optic nerve involvement can be found due to inflammation at the orbital apex. Corticosteroid administration is a management of THS with pain relief generally occurring in the first 72 hours. However, corticosteroid administration is not significantly associated with nerve dysfunction or visual acuity improvement.This article is a case report of women with STH and optic nerve involvement.Keywords: Tolosa Hunt syndrome, painful ophtalmoplegia, orbital apex, superior orbital fissureABSTRAKSindrom Tolosa Hunt (STH) adalah sindrom klinik yang sangat jarang, yang ditandai oleh nyeri kepala unilateral disertai disfungsi dan nyeri saraf penggerak bola mata (painful ophtamloplegia). Pada beberapa kasus, dapat ditemukan keterlibatan saraf optikus akibat inflamasi pada apeks orbita. Pemberian kortikosteroid merupakan tatalaksana STH dengan perbaikan nyeri umumnya terjadi pada 72 jam pertama. Meskipun demikian pemberian kortikosteroid tidak berhubungan secara signifikan dengan perbaikan disfungsi saraf penggerak bola mata maupun tajam penglihatan. Artikel ini merupakan laporan kasus perempuan dengan STH dan keterlibatan saraf optikus.Kata kunci: Sindrom Tolosa Hunt, painful ophtalmoplegia, apeksorbita, fisura orbitalis superior

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