scholarly journals Impact of Haplotype TNF-LTA Locus with Susceptibility to Cervical Cancer in Indian Population

2014 ◽  
pp. 1-18
Author(s):  
Indu Kohaar ◽  
◽  
Showket Hussain ◽  
Anoop Kumar ◽  
Pallavi Singhal ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Indian Population

Effect of aberrant promoter methylation ofFHITandRASSF1Agenes on susceptibility to cervical cancer in a North Indian population

Biomarkers ◽  
2008 ◽  
Vol 13 (6) ◽  
pp. 597-606 ◽  
Author(s):  
M. Kausar Neyaz ◽  
R. Suresh Kumar ◽  
Showket Hussain ◽  
Samar Naqvi ◽  
Indu Kohaar ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Promoter Methylation ◽  
Indian Population ◽  
North Indian Population ◽  
Aberrant Promoter Methylation

scholarly journals Perception of Human Papillomavirus Infection, Cervical Cancer and HPV Vaccination in North Indian Population

PLoS ONE ◽  
2014 ◽  
Vol 9 (11) ◽  
pp. e112861 ◽  
Author(s):  
Showket Hussain ◽  
Vilas Nasare ◽  
Malasha Kumari ◽  
Shashi Sharma ◽  
Mohammad Aijaz Khan ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Human Papillomavirus ◽  
Indian Population ◽  
Hpv Vaccination ◽  
North Indian Population ◽  
Human Papillomavirus Infection ◽  
Papillomavirus Infection

Effect of NBS1 Gene Polymorphism on the Risk of Cervix Carcinoma in a Northern Indian Population

2008 ◽  
Vol 23 (3) ◽  
pp. 133-139 ◽  
Author(s):  
R.C. Sobti ◽  
M. Shekari ◽  
D.M. Kordi Tamandani ◽  
P. Kaur ◽  
V. Suri ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Immune Response ◽  
Oral Contraceptives ◽  
Indian Population ◽  
Cervix Cancer ◽  
Cervix Carcinoma ◽  
Nbs1 Gene ◽  
Increased Risk ◽  
History Of ◽  
Cellular Immune

Cervical cancer is one of the most common neoplastic diseases affecting women, with a worldwide incidence of almost half a million cases. A history of smoking and use of oral contraceptives have been confirmed to be risk factors for cervical cancer. Genetic susceptibility and immune response, especially impaired cellular immune response, may well be related to the development of cervical cancer. NBS1 is one of the key proteins participating in the recognition and repair of double-strand breaks that may lead to genomic instability and cancer if unrepaired. The objective of the present study was therefore to investigate NBS1 Glu185Gln gene polymorphisms and the risk of cervix cancer in a northern Indian population. We found that passive smokers having particular NBS1 genotypes (Glu/Gln, Gln/Gln or Glu/Gln + Gln/Gln) have an increased risk of developing cervix cancer (OR 5.21, p=0.000001; OR 4.60, p=0.001; OR 5.10, p=0.0000009, respectively). The risk was increased 2.4-fold in oral contraceptive users with a Glu/Gln genotype. We conclude that the risk of cervical cancer is increased in passive smokers and in users of oral contraceptives with certain NBS1 genotypes.

Cyclooxygenase-2 Gene Polymorphisms and Risk of Cervical Cancer in a North Indian Population

2010 ◽  
Vol 20 (4) ◽  
pp. 625-630 ◽  
Author(s):  
Saumya Pandey ◽  
Rama Devi Mittal ◽  
Madhu Srivastava ◽  
Kirti Srivastava ◽  
Balraj Mittal
Keyword(s):  
Cervical Cancer ◽  
Gene Polymorphisms ◽  
Indian Population ◽  
Cyclooxygenase 2 ◽  
North Indian Population
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