scholarly journals Does Advice Based on Less Restrictive Sucrose Intake Affect Glycaemic Control in Individuals with Established Type 2 Diabetes?

2014 ◽  
pp. 1-14
Author(s):  
Jacqueline Cleator ◽  
Karen Allan ◽  
Elizabeth Smith ◽  
Gemma Jaggard ◽  
John Wilding
2007 ◽  
Vol 61 (6) ◽  
pp. 916-919
Author(s):  
E. O. Okoro ◽  
S. O. Funsho ◽  
O. A. Oyedokun ◽  
B. A. Oyejola

2013 ◽  
Vol 3 (1) ◽  
pp. 11-18 ◽  
Author(s):  
Zafar Ahmed Latif ◽  
Md. Faruque Pathan ◽  
Md. Nazrul Islam Siddiqui ◽  
MA Mannan ◽  
SM Ashrafuzzaman ◽  
...  

Objective: To present results from the Bangladesh cohort of the A1chieve study receiving insulin detemir (Levemir) ± oral anti diabetic drugs. Methods: Out of 1093 patients recruited from 49 sites in Bangladesh, 370 were initiated on insulin detemir (Levemir).Study visits were defined as baseline, interim (around 12 weeks from baseline) and final (around 24 weeks from baseline) visit. Results: Glycaemic control was poor in all the groups at baseline. In the entire cohort at 24 weeks, significant reductions from baseline were observed in mean HbA1c (from 10.0 % to 7.2%, p<0.001), FPG (from 10.5 to 6.7 mmol/L, p<0.001) and PPPG (from 15.3 to 8.9 mmol/L, p<0.001) levels. Overall 45.5% of the participants achieved target HbA1c level of < 7% after 24 weeks. The rate of all hypoglycaemic events in the entire cohort reduced from 1.34 (baseline) to 0.12 events/person year after 24 weeks of insulin detemir therapy (p<0.0001). There was no clinically relevant change in body weight in insulin naïve or prior insulin users groups after 24 weeks of insulin detemir therapy. Conclusions: The current study suggests that insulin detemir may be considered as a safe and effective option for initiating insulin therapy for type 2 diabetes in Bangladesh. Birdem Med J 2013; 3(1): 11-18 DOI: http://dx.doi.org/10.3329/birdem.v3i1.17121


Diabetes ◽  
2019 ◽  
Vol 68 (Supplement 1) ◽  
pp. 774-P
Author(s):  
YOSHITAKA HASHIMOTO ◽  
MASAHIDE HAMAGUCHI ◽  
AYUMI KAJI ◽  
RYOSUKE SAKAI ◽  
RYO INOUE ◽  
...  

2011 ◽  
pp. 5-10
Author(s):  
Huu Dang Tran

The incretins are peptide hormones secreted from the gut in response to food. They increase the secretion of insulin. The incretin response is reduced in patients with type 2 diabetes so drugs acting on incretins may improve glycaemic control. Incretins are metabolised by dipeptidyl peptidase, so selectively inhibiting this enzyme increases the concentration of circulating incretins. A similar effect results from giving an incretin analogue that cannot be cleaved by dipeptidyl peptidase. Studies have identified other actions including improvement in pancreatic β cell glucose sensitivity and, in animal studies, promotion of pancreatic β cell proliferation and reduction in β cell apoptosis.


2017 ◽  
Vol 24 (4) ◽  
pp. 384-403 ◽  
Author(s):  
Demetres Leonidas ◽  
Joseph Hayes ◽  
Atsushi Kato ◽  
Vassiliki Skamnaki ◽  
Demetra Chatzileontiadou ◽  
...  

2014 ◽  
Vol 10 ◽  
pp. P907-P908 ◽  
Author(s):  
Jolien Janssen ◽  
Esther van den Berg ◽  
Michaela Mattheus ◽  
Odd Erik Johansen ◽  
Geert Jan Biessels

Sign in / Sign up

Export Citation Format

Share Document