scholarly journals Cancer Care Ayurvedic perspective-A Review

The Healer ◽  
2021 ◽  
Vol 2 (02) ◽  
pp. 62-68
Author(s):  
Arshathjyothi ◽  
RamaKant Yadava
Keyword(s):  
Cancer Care ◽  
Treatment Modality ◽  
Research Question ◽  
Integrative Treatment ◽  
Classical Literature ◽  
Anticancer Activities ◽  
Cancer Management

The classical literature of Ayurveda explains the clinical entities of Arbuda and Granthi mentioned in Sushrutha Samhita that resemble Cancer. Anticancer activities of various herbs are known. Effective integrative treatment modality in Cancer still exists as a research question. The multidimensional Ayurvedic approach can be effective in cancer care which includes preventive, curative, and restorative aspects. This article is a review regarding the potential of Ayurvedic aspects of Cancer management.

Quality Measures for Symptoms and Advance Care Planning in Cancer: A Systematic Review

2006 ◽  
Vol 24 (30) ◽  
pp. 4933-4938 ◽  
Author(s):  
Karl A. Lorenz ◽  
Joanne Lynn ◽  
Sydney Dy ◽  
Anne Wilkinson ◽  
Richard A. Mularski ◽  
...  
Keyword(s):  
Advance Care Planning ◽  
Cancer Care ◽  
English Language ◽  
Basic Research ◽  
Quality Measures ◽  
Self Report ◽  
Care Planning ◽  
Cancer Management ◽  
Patient Goals ◽  
Advance Care

Purpose Measuring quality of care for symptom management and ascertaining patient goals offers an important step toward improving palliative cancer management. This study was designed to identify systematically the quality measures and the evidence to support their use in pain, dyspnea, depression, and advance care planning (ACP), and to identify research gaps. Methods English-language documents were selected from MEDLINE, Cumulative Index to Nursing and Allied Health, PsycINFO (1995 to 2005); Internet-based searches; and contact with measure developers. We used terms for each domain to select studies throughout the cancer care continuum. We included measures that expressed a normative relationship to quality, specified the target population, and specified the indicated care. Dual data review and abstraction was performed by palliative care researchers describing populations, testing, and attributes for each measure. Results A total of 4,599 of 5,182 titles were excluded at abstract review. Of 537 remaining articles, 19 contained measures for ACP, six contained measures for depression, five contained measures for dyspnea, and 20 contained measures for pain. We identified 10 relevant measure sets that included 36 fully specified or fielded measures and 14 additional measures (16 for pain, five for dyspnea, four for depression, and 25 for ACP). Most measures were unpublished, and few had been tested in a cancer population. We were unable to describe the specifications of all measures fully and did not search for measures for pain and depression that were not cancer specific. Conclusion Measures are available for assessing quality and guiding improvement in palliative cancer care. Existing measures are weighted toward ACP, and more nonpain symptom measures are needed. Additional testing is needed before the measures are used for accountability, and basic research is required to address measurement when self-report is impaired.

scholarly journals GC/MS analysis, free radical scavenging, anticancer and β-glucuronidase inhibitory activities of Trillium govanianum rhizome

2015 ◽  
Vol 10 (3) ◽  
pp. 577 ◽  
Author(s):  
Shafiq ur Rahman ◽  
Muhammad Ismail ◽  
Muhammad Raza Shah ◽  
Marcello Iriti ◽  
Muhammad Shahid
Keyword(s):  
Free Radical ◽  
Saturated Fatty Acids ◽  
Radical Scavenging ◽  
Free Radical Scavenging ◽  
Chloroform Fraction ◽  
Anticancer Activities ◽  
Cancer Management ◽  
Scavenging Capacity ◽  
Phytochemical Constituents ◽  
Trillium Govanianum

<p>The current study aims to investigate the phytochemical constituents, antioxidant, β-glucuronidase inhibitory and anticancer activities of<em> Trillium govanianum</em> rhizome. Phytochemical screening revealed the presence of steroidal glycosides, saponins, sterols, flavonoids and carbohydrates. GC/MS analyses of n-hexane fraction identified 12 compounds, including 70% unsaturated and 30% saturated fatty acids. Higher free radical scavenging capacity was observed in n-hexane and chloroform fraction compared with the other fractions. Based on IC<sub>50</sub> (μg/mL) values, antiproliferative activity on HeLa cells was observed for  chloroform (0.8 ± 0.2), ethyl acetate (1.4 ± 0.1) and butanol (1.6 ± 0.3) fractions by comparison to anticancer drug doxorubicin (0.3 ± 0.0). Similarly, all fractions exhibited cytotoxicity on PC-3 cells. Moreover, the methanol extract (IC<sub>50</sub>: 140.8 ± 3.8) and butanol fraction (196.2 ± 1.9) exhibited a moderate level of β-glucuronidase inhibitory activity. These findings may validate the folkloric uses of<em> T. govanianum</em> rhizome in cancer management, and can be a promising candidate as an anticancer agent.</p><p> </p>

scholarly journals Restructuring Skin Cancer Care in Ontario: A Provincial Plan

2021 ◽  
Vol 28 (2) ◽  
pp. 1183-1196
Author(s):  
John Milkovich ◽  
Tim Hanna ◽  
Carolyn Nessim ◽  
Teresa M. Petrella ◽  
Louis Weatherhead ◽  
...  
Keyword(s):  
Systematic Review ◽  
Skin Cancer ◽  
Patient Care ◽  
Cancer Care ◽  
Literature Search ◽  
Performance Metrics ◽  
Grey Literature ◽  
Care Needs ◽  
Cancer Management ◽  
Cancer Biopsy

There is a global rise in skin cancer incidence, resulting in an increase in patient care needs and healthcare costs. To optimize health care planning, costs, and patient care, Ontario Health developed a provincial skin cancer plan to streamline the quality of care. We conducted a systematic review and a grey literature search to evaluate the definitions and management of skin cancer within other jurisdictions, as well as a provincial survey of skin cancer care practices, to identify care gaps. The systematic review did not identify any published comprehensive skin cancer management plans. The grey literature search revealed skin cancer plans in isolated regions of the United Kingdom (U.K.), National Institute for Health and Care Excellence (NICE) guidelines for skin cancer quality indicators and regional skin cancer biopsy clinics, and wait time guidelines in Australia and the U.K. With the input of the Ontario Cancer Advisory Committee (CAC), unique definitions for complex and non-complex skin cancers and the appropriate cancer services were created. A provincial survey of skin cancer care yielded 44 responses and demonstrated gaps in biopsy access. A skin cancer pathway map was created and a recommendation was made for regional skin cancer biopsy clinics. We have created unique definitions for complex and non-complex skin cancer and a skin cancer pathways map, which will allow for the implementation of both process and performance metrics to address identified gaps in care.

Using a framework for resource stratification to adapt palliative care guidelines to Sub-Saharan Africa.

2017 ◽  
Vol 35 (31_suppl) ◽  
pp. 145-145
Author(s):  
Maria Cristina Dans ◽  
Kunuz Abdella ◽  
Dinah Baah-Odoom ◽  
Rinty Kintu ◽  
Israel Kolawole ◽  
...  
Keyword(s):  
Palliative Care ◽  
Cancer Care ◽  
The United States ◽  
Sub Saharan Africa ◽  
Rational Approach ◽  
Care Providers ◽  
Nccn Guidelines ◽  
Cancer Management ◽  
The Us ◽  
Sub Saharan

145 Background: The National Comprehensive Cancer Network (NCCN) is a not-for-profit alliance of 27 leading cancer centers in the United States (US), but the NCCN’s mission to improve cancer care extends world-wide. Nearly half of the registered users of the NCCN Guidelines are based outside the US, and the NCCN has developed a process for adapting its Guidelines to lower-resourced settings. The cancer burden in Sub-Saharan Africa (SSA) is significant – by 2030, annual cancer deaths in the region are projected to reach 1,000,000 people – and most cancers diagnosed in SSA are late-stage. Methods: The NCCN Framework outlines a rational approach for constructing cancer management systems to provide the highest achievable care. Each of the 4 NCCN Framework levels builds on the one before it, so care can evolve as resources grow: “Basic Resources” are essential for care; “Core Resources” add services improving disease outcomes; and “Enhanced Resources” include more cost-prohibitive services. The Guidelines themselves are the final level: evidence-based, consensus-driven recommendations from each NCCN Panel. Resource-stratification begins with modification of the Guidelines by a NCCN Framework Committee within each Panel. Results: In the case of SSA, organizers from the NCCN, American Cancer Society, Clinton Health Access Initiative, and IBM arranged 3 consensus meetings in which resource-stratified drafts of the Guidelines for Palliative Care and Cancer Pain will be refined by a committee of NCCN representatives, oncologists, and palliative care providers from Burundi, Ethiopia, Ghana, Kenya, Nigeria, Uganda, and the US. Important themes emerging from the first meeting included early screening for palliative care needs, even before tissue diagnosis, in areas with limited availability of anti-cancer therapy. In addition, cultural differences on the topic of “Physician-Aid-in-Dying” led to its replacement with guidance on caring for patients expressing a wish to die. Conclusions: Collaboration with colleagues in SSA, and other areas around the globe, to resource-stratify NCCN Guidelines will allow more systematic use of the guidelines and improve the quality, effectiveness, and efficiency of cancer care.

scholarly journals Role of real-world evidence in informing cancer care: lessons from colorectal cancer

2019 ◽  
Vol 26 (1) ◽  
Author(s):  
A. Batra ◽  
W. Y. Cheung
Keyword(s):  
Colorectal Cancer ◽  
Real World ◽  
Cancer Care ◽  
Clinical Care ◽  
Real World Data ◽  
Cancer Management ◽  
Randomized Controlled ◽  
Real World Evidence ◽  
Research Questions

The term “real-world evidence” (rwe) describes the analysis of data that are collected beyond the context of clinical trials. The use and application of rwe have become increasingly common and relevant, especially in oncology, because there is growing recognition that randomized controlled trials (rcts) might not be sufficiently representative of the entire patient population that is affected by cancer, and that specific clinical research questions might be best addressed by real-world data. In this brief review, our main aim is to highlight the role of rwe in informing cancer care, particularly focusing on specific examples from colorectal cancer. Our hope is to illustrate the ways in which rwe can complement rcts in improving the understanding of cancer management and how rwe can facilitate cancer treatment decisions for real-world patients encountered in routine clinical care.

scholarly journals 86P Overview of breast cancer management: Yangon private sector cancer care

2016 ◽  
Vol 27 ◽  
pp. ix25
Author(s):  
S. Mon ◽  
T.T. Aye ◽  
M. Khine ◽  
E.P.P. Aung ◽  
A.S. Nyunt ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Private Sector ◽  
Cancer Care ◽  
Cancer Management ◽  
Breast Cancer Management

scholarly journals FINANCIAL COSTS OF PAEDIATRIC CANCER MANAGEMENT IN AFRICA: SYSTEMATIC REVIEW AND META-ANALYSIS

2021 ◽  
Author(s):  
Criss Koba ◽  
Désiré Kulimba ◽  
Oscar Numbi ◽  
Murielle Nkumuyaya ◽  
Yves Chabu ◽  
...  
Keyword(s):  
Systematic Review ◽  
Childhood Cancer ◽  
Cancer Care ◽  
Financial Burden ◽  
Meta Analysis ◽  
World Health ◽  
African Countries ◽  
Financing System ◽  
Cancer Management ◽  
Financial Costs

Background: Pediatric cancer is one of the leading causes of death and a matter of constant concern worldwide. The objective of this study was to estimate the financial cost of treating children suffering from cancer in Africa. Methods: We conducted a systematic review and meta-analysis of expert opinions with peer review by searching PubMed and other databases for World Health Organization data for the African region published in French and English between March 2000 and March 2020. The key search terms included ‘cost’, ‘cancer’ and ‘child’; we selected articles that specifically addressed the financial costs of childhood cancer in African countries. Results: Of 79 articles found, 15 met the inclusion criteria; four of the articles came from Rwanda. Cancer care was a heavy financial burden in most of the countries studied, although costs varied from country to country; the average healthcare expenditure was US$1017.39 ± US$319.1 per year. In countries without a health insurance system, the highest proportion of cancer care costs, 62.7%, was indirect (e.g., travel costs to a different country for oncology care), whereas in countries with a cancer financing system, the direct cost of treatment was low, 37.3%. Conclusion: The cost of treating childhood cancer is high in Africa in relation to the standard of living of individuals residing in this region. More studies on financing cancer care on this continent could improve treatment and patient management. Keywords: Childhood cancer, financial costs, Africa, systematic review, meta-analysis.

Cancer care in the time of COVID-19: A conceptual framework to improve cancer outcomes during a pandemic.

2021 ◽  
Vol 39 (15_suppl) ◽  
pp. e18628-e18628
Author(s):  
Vivienne Milch ◽  
Cleola Anderiesz ◽  
Debra Hector ◽  
Scott Turnbull ◽  
Melissa Austen ◽  
...  
Keyword(s):  
Decision Making ◽  
Health System ◽  
Conceptual Framework ◽  
Cancer Patients ◽  
Cancer Care ◽  
Cancer Outcomes ◽  
System Planning ◽  
Screening Programs ◽  
Cancer Management ◽  
Health System Planning

e18628 Background: At the start of the COVID-19 pandemic, a plan for cancer management during a pandemic did not exist. It soon became clear that without proper planning, cancer outcomes would worsen. Cancer patients are at increased risk of COVID-19 infection, morbidity, and mortality. Health sectors internationally reduced or paused non-urgent cancer care to protect cancer patients from COVID-19. However, disproportionate delays in screening, diagnosis, and treatment can unduly impact cancer outcomes, and backlogs can further burden a strained health system. Tailored approaches to cancer management are required which balance health resource availability along with the risks of exposure and benefits of treatment. Australia’s relatively low COVID-19 case numbers afforded Cancer Australia an opportunity to proactively plan for optimal cancer management during this, and future, pandemics. Methods: Cancer Australia’s Cancer care in the time of COVID-19: A conceptual framework for the management of cancer during a pandemic (the framework) maps evidence-based cancer care considerations in relation to a health system’s capacity across acute and recovery pandemic phases, in relation to steps of the cancer care pathway. The framework promotes infection control and resource prioritisation in the context of innovative care models, triaging approaches and individualised treatment plans, underpinned by effective communication and shared decision-making. Results: The framework supports health system planning and risk-stratified approaches to guide decision-making and improve cancer outcomes. Many aspects of cancer care are recommended to continue (to varying degrees) in most pandemic phases, with modifications or pauses in some aspects of care as the pandemic curve approaches or exceeds health system capacity. Principles of the framework were employed during the second wave of COVID-19 in the Australian state of Victoria, with continuation of cancer screening programs, diagnostic investigations, and treatments wherever it was safe to do so. This resulted in reductions in cancer services and treatment being relatively smaller than in the first wave. Conclusions: Cancer management in a pandemic is not a one-size-fits-all. Countries and jurisdictions need to tailor cancer care according to the risk of the health system becoming overwhelmed. The framework guides optimal cancer care to improve outcomes for people with cancer, while minimising COVID-19 infection. As further evidence becomes available from this pandemic or in future pandemics, this framework can be refined to inform ongoing and future pandemic health system planning.

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