scholarly journals Cat-scratch Disease with Parinaud's Oculoglandular Syndrome

2020 ◽  
Vol 58 (1) ◽  
pp. 48-51
Author(s):  
Ana Sousa Menezes ◽  
◽  
Daniela Ribeiro ◽  
Antonio Fontes Lima ◽  
◽  
...  
2018 ◽  
Vol 379 (18) ◽  
pp. e31 ◽  
Author(s):  
Catalina Arango-Ferreira ◽  
Jorge Castano

2005 ◽  
Vol 132 (3) ◽  
pp. 353-358 ◽  
Author(s):  
Gerd Jürgen Ridder ◽  
Carsten Christof Boedeker ◽  
Katja Technau-Ihling ◽  
Anna Sander

OBJECTIVE: The bacteria Bartonella henselae has been known as the principal causative agent of cat-scratch disease (CSD) since 1992. It is an important cause of infectious lymphadenopathies in the head and neck. Nevertheless, CSD often remains unrecognized in cases of cervicofacial lymph node enlargement. STUDY DESIGN: Between January 1997 and May 2003, we conducted a prospective clinical study including 721 patients with primarily unclear masses in the head and neck. RESULTS: CSD was diagnosed by serology and molecular investigations in 99 patients (13.7%; median age 33 years). Cervicofacial lymphadenopathy was the most common manifestation. Atypical manifestation of CSD including Parinaud's oculoglandular syndrome, swelling of the parotid gland and erythema nodosum were diagnosed in 8.1%, 8.1%, and 2.0% of cases, respectively. CONCLUSIONS: Our results demonstrate that CSD is a major cause of enlarged cervicofacial lymph nodes and should therefore be included in the differential diagnosis of lymphadenopathy in the head and neck region.


Ophthalmology ◽  
1985 ◽  
Vol 92 (9) ◽  
pp. 1282-1287 ◽  
Author(s):  
Douglas J. Wear ◽  
Raga H. Malaty ◽  
Lorenz E. Zimmerman ◽  
Ted L. Hadfield ◽  
Andrew M. Margileth

PEDIATRICS ◽  
1968 ◽  
Vol 42 (5) ◽  
pp. 803-818
Author(s):  
A. M. Margileth

Of 145 patients with nonbacterial lymphadenitis observed over a period of 10 years, 115 had clinical cat scratch disease (CSD) with a positive cat scratch antigen skin test. In this group 86% had a typical benign course of CSD; the remaining 16 (14%) had an atypical form. These unusual forms were: Parinaud's oculoglandular syndrome in 7, encephalopathy in 3, atypical pneumonia in 2, and recurrent suppurative lymphadenopathy in 1. Two typical cases occurred after a dog scratch or bite, and one after a monkey scratch. The disease was most prevalent in late fall and early winter; 80% of patients were under age 20 years. Primary lesions were detected in 55%, node suppuration occurred in 26%, and lymphadenopathy lasted 2 weeks to 2 months in most patients. Symptoms were absent in 35% of cases. Fever occurred in 26%, and exanthem was present in 4%. Lymphadenopathy was most common in the extremities (57%), and head and neck (43%). Cat scratch antigen was found to be a reliable diagnostic skin test. A negative test was found in 98% of control patients; a positive test was found in 94% of patients who were clinically suspected to have CSD and a history of cat scratch. Management consisted of reassurance, symptomatic therapy, and closed aspiration of enlarged nodes if suppuration occurred. Antibiotics were not effective. The disease is self-limited and has an excellent prognosis in the majority of patients. An etiologic agent could not be isolated in this study. Until the causative agent is known, it will be difficult to carry out preventive measures.


2020 ◽  
Vol 104 (12) ◽  
pp. 1640-1646 ◽  
Author(s):  
Alan Johnson

Cat scratch disease (CSD) in humans is caused by infection with Bartonella henselae or other Bartonella spp. The name of the disease reflects the fact that patients frequently have a history of contact (often involving bites or scratches) with infected cats. Patients with CSD typically develop lesions at the site where the skin is broken together with regional lymphadenopathy but may go on to exhibit systemic symptoms and with deep-seated infections at a range of sites including the eye. Patients with CSD may present with a range of inflammatory eye conditions, including Parinaud’s oculoglandular syndrome, neuroretinitis, multifocal retinitis, uveitis and retinal artery occlusion. Bartonella spp. are fastidious bacteria that are difficult to culture from clinical specimens so microbiological diagnosis is frequently made on the basis of positive serology for anti-Bartonella antibodies or detection of bacterial DNA by PCR. Due to the lack of clinical trials, the evidence base for optimal management of patients with CSD-associated eye infections (including the role of antibiotics) is weak, being derived from single reports or small, uncontrolled case series.


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