scholarly journals Prenatal diagnosis of caudal regression syndrome without maternal diabetes mellitus

2011 ◽  
Vol 12 (3) ◽  
pp. 186-188 ◽  
Author(s):  
Ahmet Ozgur Yeniel ◽  
Ahmet Mete Ergenoglu ◽  
Sermet Sagol
2019 ◽  
Vol 38 (2) ◽  
pp. 132-134
Author(s):  
Md Abu Bakkar Siddique ◽  
Sudip Saha ◽  
Kallol Bose ◽  
Sudipta Ghorai ◽  
Kalimuddin Khan

We report a case of sirenomelia baby (Mermaid syndrome) born to a twenty three years old female at 37 weeks of gestation. Sirenomelia is characterized by fusion of the lower limbs with absent kidneys, absent external genitalia and other gastrointestinal defects. It results from the failure of normal vascular supply from the lower aorta in vitro, maternal Diabetes mellitus has been associated with caudal regression syndrome and sirenomelia.  


2005 ◽  
Vol 25 (3) ◽  
pp. 264-266 ◽  
Author(s):  
Chih-Ping Chen ◽  
Chen-Yu Chen ◽  
Ching-Yi Lin ◽  
Sheng-Wen Shaw ◽  
Wayseen Wang ◽  
...  

2021 ◽  
Vol 224 (2) ◽  
pp. S188-S189
Author(s):  
Stacey Gold ◽  
Catherine Lopez ◽  
Jessica L. Quistorff ◽  
Sarah Downs ◽  
Sara Iqbal ◽  
...  

Hypertension ◽  
2019 ◽  
Vol 73 (1) ◽  
Author(s):  
Joana Oliveira Miranda ◽  
Rui João Cerqueira ◽  
Henrique Barros ◽  
José Carlos Areias

Intrauterine fetal conditions can have lifelong cardiovascular effects. The impact of maternal diabetes mellitus on children’s cardiovascular profile is not well established. The goal of this study was to explore the association between maternal diabetes mellitus and offspring’s blood pressure (BP) ≤10 years of age. Generation XXI is a prospective birth cohort, which enrolled 8301 mother-offspring pairs, including 586 (7.1%) children of diabetic mothers. The associations between maternal diabetes mellitus and BP at 4, 7, and 10 years of age was modeled using linear regression. A mixed-effects model was built to assess differences in BP variation over time. Path analysis was used to quantify effects of potential mediators. Maternal diabetes mellitus was associated with higher BP in offspring at the age of 10 (systolic: β, 1.48; 95% CI, 0.36–2.59; and diastolic: β, 0.86; 95% CI, 0.05–1.71). This association was independent of maternal perinatal characteristics, and it was mediated by child’s body mass index and, to a lesser extent, by gestational age, type of birth, and birth weight (indirect effect proportion, 73%). No significant differences in BP were found at 4 and 7 years of age. Longitudinal analysis showed an accelerated systolic BP increase on maternal diabetes mellitus group (β, 1.16; 95% CI, 0.03–2.28). These finding were especially relevant in males, suggesting sex differences in the mechanisms of BP prenatal programing. Our results provide further evidence that maternal diabetes mellitus is associated with high BP late in childhood, demonstrating a significant role of child’s body mass in the pathway of this association.


Sign in / Sign up

Export Citation Format

Share Document