scholarly journals Prognostic value of mediastinal lymph node enlargement in chronic interstitial lung disease

2021 ◽  
Author(s):  
Stefano Grecuccio ◽  
◽  
Nicola Sverzellati ◽  
Elisabetta Uslenghi ◽  
Antonella Caminati ◽  
...  
Keyword(s):  
Lymph Node ◽  
Interstitial Lung Disease ◽  
Lung Disease ◽  
Prognostic Value ◽  
Mediastinal Lymph Node ◽  
Lymph Node Enlargement

scholarly journals The lungs were on fire: a pilot study of 18F-FDG PET/CT in idiopathic-inflammatory-myopathy-related interstitial lung disease

2021 ◽  
Author(s):  
Junyu Liang ◽  
Heng Cao ◽  
Yinuo Liu ◽  
Bingjue Ye ◽  
Yiduo Sun ◽  
...  
Keyword(s):  
Lymph Node ◽  
Interstitial Lung Disease ◽  
Lung Disease ◽  
Ct Scan ◽  
Mediastinal Lymph Node ◽  
Inflammatory Myopathy ◽  
Idiopathic Inflammatory Myopathy ◽  
Pet Ct ◽  
Bilateral Lung ◽  
Pet Ct Scan

Abstract Background: Interstitial lung disease (ILD) and its rapid progression (RP) were main contributors to unfavorable outcome of idiopathic inflammatory myopathy (IIM) patients. This study aimed at identifying the clinical value of PET/CT scan in IIM-ILD patients as well as constructing a predicting model for RP-ILD.Methods: Adult IIM-ILD patients who were hospitalized at four divisions of the First Affiliated Hospital, Zhejiang University School of Medicine (FAHZJU) from Jannuary 1st 2017 to December 31st 2020 were reviewed. PET/CT scan as well as other factors of patients who met the inclusion and exclusion criteria were collected and analyzed.Results: A total of 61 IIM-ILD patients were finally enrolled into this study. Twenty-one patients (34.4%) developed RP-ILD and 24 patients (39.3%) died in follow-up. After false discovery rate (FDR) correction, percent-predicted diffusing capacity of the lung for carbon monoxide (DLCO%, P=0.014), bilateral lung mean standard uptake value (SUVmean, P=0.014) and abnormal mediastinal lymph node (P=0.045) were significantly different in comparison between RP-ILD and non-RP-ILD groups. A “DLM” model was hereby established by including the above three values to predict RP-ILD with a cutoff value of ≥2 and an area under the curve (AUC) of 0.905. Higher bilateral lung SUVmean (P=0.019) and spleen SUVmean (P=0.011) were observed in IIM-ILD patients who died within three months, and a moderate correlation was recognized between the two values. Conclusions: Elevated bilateral lung SUVmean and abnormal mediastinal lymph node were associated with RP-ILD in IIM-ILD patients. The “DLM” model was valuable in predicting RP-ILD and demanded further evaluation.

Mediastinal lymph node enlargement on CT scans in idiopathic pulmonary fibrosis

1992 ◽  
Vol 28 (5) ◽  
pp. 705
Author(s):  
Joong Mo Ahn ◽  
Jung Gi Im ◽  
In Kyu Yu ◽  
Hyeon Seog Kim ◽  
Dae Young Kim ◽  
...  
Keyword(s):  
Lymph Node ◽  
Idiopathic Pulmonary Fibrosis ◽  
Pulmonary Fibrosis ◽  
Mediastinal Lymph Node ◽  
Ct Scans ◽  
Lymph Node Enlargement

The Prognostic Value of the GAP Model In Chronic Interstitial Lung Disease

CHEST Journal ◽  
2014 ◽  
Vol 145 (4) ◽  
pp. 672-674 ◽  
Author(s):  
Athol U. Wells ◽  
Katerina M. Antoniou
Keyword(s):  
Interstitial Lung Disease ◽  
Lung Disease ◽  
Prognostic Value ◽  
Gap Model

Tuberculous Lymphadenopathy Causing Dysphagia: Report of Two Cases

1998 ◽  
Vol 6 (3) ◽  
pp. 208-211
Author(s):  
Omer S Alamoudi ◽  
Julio S Montaner ◽  
Kenneth Evans ◽  
J Mark FitzGerald
Keyword(s):  
Mycobacterium Tuberculosis ◽  
Lymph Node ◽  
Mediastinal Lymph Node ◽  
Hiv Positive ◽  
Antituberculous Therapy ◽  
First Line ◽  
External Compression ◽  
Lymph Node Enlargement

We report two cases of tuberculous lymphadenopathy causing dysphagia. The first patient was HIV positive and the second patient had immigrated recently from India. Culture in both patients grew Mycobacterium tuberculosis that was fully sensitive to first line drugs. Dysphagia may result from intrinsic or extrinsic involvement of the esophagus. Extrinsic involvement is more common and results from cervical and mediastinal lymph node enlargement (as in these 2 cases) that causes external compression on the wall of the esophagus. The dysphagia subsided completely after 4 weeks of antituberculous therapy in both cases.

Diagnostic Yield of Transbronchial Histology Needle Aspiration in Patients with Mediastinal Lymph Node Enlargement

Respiration ◽  
2003 ◽  
Vol 70 (6) ◽  
pp. 631-635 ◽  
Author(s):  
Frank H.W. Hermens ◽  
Ton C.A. van Engelenburg ◽  
Frank J. Visser ◽  
Frederik B.J.M. Thunnissen ◽  
René Termeer ◽  
...  
Keyword(s):  
Lymph Node ◽  
Diagnostic Yield ◽  
Mediastinal Lymph Node ◽  
Needle Aspiration ◽  
Lymph Node Enlargement
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