scholarly journals Implication of cerebral circulation time in intracranial stenosis measured by digital subtraction angiography on cerebral blood flow estimation measured by arterial spin labeling

2016 ◽  
Vol 22 (5) ◽  
pp. 481-488 ◽  
Author(s):  
Kay Jann ◽  
Martinus Hauf ◽  
Frauke Kellner Weldon ◽  
Marwan El Koussy ◽  
Claus Kiefer ◽  
...  
Keyword(s):  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Digital Subtraction Angiography ◽  
Cerebral Circulation ◽  
Arterial Spin Labeling ◽  
Spin Labeling ◽  
Intracranial Stenosis ◽  
Digital Subtraction ◽  
Flow Estimation ◽  
Cerebral Circulation Time

scholarly journals Planning-free cerebral blood flow territory mapping in patients with intracranial arterial stenosis

2016 ◽  
Vol 37 (6) ◽  
pp. 1944-1958 ◽  
Author(s):  
Daniel F Arteaga ◽  
Megan K Strother ◽  
L Taylor Davis ◽  
Matthew R Fusco ◽  
Carlos C Faraco ◽  
...  
Keyword(s):  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Digital Subtraction Angiography ◽  
Gold Standard ◽  
Arterial Spin Labeling ◽  
Spin Labeling ◽  
Circle Of Willis ◽  
Atherosclerotic Disease ◽  
Digital Subtraction ◽  
Intracranial Atherosclerotic Disease

A noninvasive method for quantifying cerebral blood flow and simultaneously visualizing cerebral blood flow territories is vessel-encoded pseudocontinuous arterial spin labeling MRI. However, obstacles to acquiring such information include limited access to the methodology in clinical centers and limited work on how clinically acquired vessel-encoded pseudocontinuous arterial spin labeling data correlate with gold-standard methods. The purpose of this work is to develop and validate a semiautomated pipeline for the online quantification of cerebral blood flow maps and cerebral blood flow territories from planning-free vessel-encoded pseudocontinuous arterial spin labeling MRI with gold-standard digital subtraction angiography. Healthy controls (n = 10) and intracranial atherosclerotic disease patients (n = 34) underwent 3.0 T MRI imaging including vascular (MR angiography) and hemodynamic (cerebral blood flow-weighted arterial spin labeling) MRI. Patients additionally underwent catheter and/or CT angiography. Variations in cross-territorial filling were grouped according to diameters of circle of Willis vessels in controls. In patients, Cohen’s k-statistics were computed to quantify agreement in perfusion patterns between vessel-encoded pseudocontinuous arterial spin labeling and angiography. Cross-territorial filling patterns were consistent with circle of Willis anatomy. The intraobserver Cohen's k-statistics for cerebral blood flow territory and digital subtraction angiography perfusion agreement were 0.730 (95% CI = 0.593–0.867; reader one) and 0.708 (95% CI = 0.561–0.855; reader two). These results support the feasibility of a semiautomated pipeline for evaluating major neurovascular cerebral blood flow territories in patients with intracranial atherosclerotic disease.

scholarly journals N-acetyl cysteine administration affects cerebral blood flow as measured by Arterial Spin Labeling MRI in patients with multiple sclerosis

Heliyon ◽  
2021 ◽  
pp. e07615
Author(s):  
Shiva Shahrampour ◽  
Justin Heholt ◽  
Andrew Wang ◽  
Faezeh Vedaei ◽  
Feroze B. Mohamed ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Arterial Spin Labeling ◽  
Spin Labeling ◽  
Acetyl Cysteine

scholarly journals Patient-Specific Detection of Cerebral Blood Flow Alterations as Assessed by Arterial Spin Labeling in Drug-Resistant Epileptic Patients

PLoS ONE ◽  
2015 ◽  
Vol 10 (5) ◽  
pp. e0123975 ◽  
Author(s):  
Ilaria Boscolo Galazzo ◽  
Silvia Francesca Storti ◽  
Alessandra Del Felice ◽  
Francesca Benedetta Pizzini ◽  
Chiara Arcaro ◽  
...  
Keyword(s):  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Arterial Spin Labeling ◽  
Spin Labeling ◽  
Patient Specific ◽  
Drug Resistant ◽  
Specific Detection ◽  
Epileptic Patients
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