Levodopa Withdrawal in Parkinson’s Disease: a Rare Cause of Fever Necessitating Intensive Care

2010 ◽  
Vol 1 (2) ◽  
pp. 52-54
Author(s):  
Umit Tapan ◽  
Gunes Arik ◽  
Neriman Defne Altintas ◽  
Ozlem Celebi ◽  
Arzu Topeli
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Intensive Care ◽  
Levodopa Withdrawal

Reappraisal of Temporary Levodopa Withdrawal (Drug Holiday) in Parkinson's Disease

1985 ◽  
Vol 313 (12) ◽  
pp. 724-728 ◽  
Author(s):  
Richard Mayeux ◽  
Yaakov Stern ◽  
Kevin Mulvey ◽  
Lucien Cote
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Drug Holiday ◽  
Levodopa Withdrawal

scholarly journals Parkinson's disease in intensive care unit: An observational study of frequencies, causes, and outcomes

2019 ◽  
Vol 22 (1) ◽  
pp. 79 ◽  
Author(s):  
Gunchan Paul ◽  
BirinderSingh Paul ◽  
ParshotumLal Gautam ◽  
G Singh ◽  
S Kaushal
Keyword(s):  
Parkinson’S Disease ◽  
Intensive Care Unit ◽  
Parkinson's Disease ◽  
Intensive Care ◽  
Observational Study

scholarly journals Treatment of Acute Delirium in a Patient with Parkinson’s Disease by Transfer to the Intensive Care Unit and Administration of Dexmedetomidine

2020 ◽  
Vol 13 (2) ◽  
pp. 159-162
Author(s):  
Morgan Lombardo ◽  
Amanda DiPiazza ◽  
Kelly Rippey ◽  
Naomi Lubarr ◽  
Elana Clar ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Intensive Care Unit ◽  
Parkinson's Disease ◽  
Intensive Care

Parkinson’s Disease in Intensive Care Unit

2014 ◽  
pp. 125-138
Author(s):  
Lionel Velly ◽  
Delphine Boumaza ◽  
Nicolas Bruder
Keyword(s):  
Parkinson’S Disease ◽  
Intensive Care Unit ◽  
Parkinson's Disease ◽  
Intensive Care

scholarly journals Evaluation of Patients with Parkinson’s Disease in Intensive Care Units: A Cohort Study

2021 ◽  
Vol 2021 ◽  
pp. 1-7
Author(s):  
Álvaro Réa-Neto ◽  
Bruna C. Dal Vesco ◽  
Rafaella S. Bernardelli ◽  
Aline M. Kametani ◽  
Mirella C. Oliveira ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Cohort Study ◽  
Intensive Care ◽  
Intensive Care Units ◽  
Historical Cohort ◽  
Worldwide Population ◽  
Severity Scores ◽  
Level Of Consciousness ◽  
Health Related

Background. Parkinson’s disease affects approximately 1% of the worldwide population older than 60 years. This number is estimated to double by 2030, increasing the global burden of the disease. Patients with Parkinson’s disease are hospitalized 1.5 times more frequently and for longer periods than those without the disease, increasing health-related costs. Objective. To compare the characteristics and outcome of patients with and without Parkinson’s disease admitted to intensive care units (ICUs). Methods. Historical cohort study of ICU admissions in a Brazilian city over 18 years. All patients with Parkinson’s disease identified were matched for age, sex, year, and place of hospitalization with patients without the disease randomly selected from the same database. Results. The study included 231 patients with Parkinson’s disease (PD group) and 462 controls without the disease (NPD group). Compared with patients in the NPD group, those in the PD group were more frequently admitted with lower level of consciousness and increased APACHE II severity score but required less frequently vasoactive drugs. In total, 42.4% of the patients in the PD group were admitted to the ICUs due to sepsis or trauma. Although these patients had longer hospital stay, the mortality rates were comparable between groups. Parkinson’s disease was not associated with mortality, even when controlled for associated factors of disease severity. Conclusion. Although patients with Parkinson’s disease were admitted with higher severity scores and remained in the ICU for a longer time, their mortality rate was not higher than that in patients without the disease.

Evaluation of Efferent Auditory System and Hearing Quality in Parkinson's Disease: Is the Difficulty in Speech Understanding in Complex Listening Conditions Related to Neural Degeneration or Aging?

2020 ◽  
pp. 1-9
Author(s):  
Nuriye Yıldırım Gökay ◽  
Bülent Gündüz ◽  
Fatih Söke ◽  
Recep Karamert
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Auditory System ◽  
Otoacoustic Emissions ◽  
Pure Tone ◽  
Pure Tone Audiometry ◽  
Auditory Pathway ◽  
Normal Hearing ◽  
System Function ◽  
Distortion Product

Purpose The effects of neurological diseases on the auditory system have been a notable issue for investigators because the auditory pathway is closely associated with neural systems. The purposes of this study are to evaluate the efferent auditory system function and hearing quality in Parkinson's disease (PD) and to compare the findings with age-matched individuals without PD to present a perspective on aging. Method The study included 35 individuals with PD (mean age of 48.50 ± 8.00 years) and 35 normal-hearing peers (mean age of 49 ± 10 years). The following tests were administered for all participants: the first section of the Speech, Spatial and Qualities of Hearing Scale; pure-tone audiometry, speech audiometry, tympanometry, and acoustic reflexes; and distortion product otoacoustic emissions (DPOAEs) and contralateral suppression of DPOAEs. SPSS Version 25 was used for statistical analyses, and values of p < .05 were considered statistically significant. Results There were no statistically significant differences in the pure-tone audiometry thresholds and DPOAE responses between the individuals with PD and their normal-hearing peers ( p = .732). However, statistically significant differences were found between the groups in suppression levels of DPOAEs and hearing quality ( p < .05). In addition, a statistically significant and positive correlation was found between the amount of suppression at some frequencies and the Speech, Spatial and Qualities of Hearing Scale scores. Conclusions This study indicates that medial olivocochlear efferent system function and the hearing quality of individuals with PD were affected adversely due to the results of PD pathophysiology on the hearing system. For optimal intervention and follow-up, tasks related to hearing quality in daily life can also be added to therapies for PD.

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