scholarly journals Lower serum 25-hydroxyvitamin D level is associated with impaired myocardial performance and left ventricle hypertrophy in newly diagnosed hypertensive patients

2015 ◽  
Vol 15 (9) ◽  
pp. 744-750 ◽  
Author(s):  
Taner Seker ◽  
Mustafa Gur ◽  
Hakan Ucar ◽  
Caner Turkoglu ◽  
Ahmet Oytun Baykan ◽  
...  
Keyword(s):  
Left Ventricle ◽  
Myocardial Performance ◽  
Newly Diagnosed ◽  
Lower Serum ◽  
Hypertensive Patients ◽  
Hydroxyvitamin D ◽  
Left Ventricle Hypertrophy ◽  
25 Hydroxyvitamin D ◽  
Ventricle Hypertrophy

Serum 25-Hydroxyvitamin D Level Is Associated With Arterial Stiffness, Left Ventricle Hypertrophy, and Inflammation in Newly Diagnosed Hypertension

2013 ◽  
Vol 61 (6) ◽  
pp. 989-994 ◽  
Author(s):  
Osman Kuloğlu ◽  
Mustafa Gür ◽  
Taner Şeker ◽  
Gülhan Yüksel Kalkan ◽  
Durmuş Yıldıray Şahin ◽  
...  
Keyword(s):  
Arterial Stiffness ◽  
Left Ventricle ◽  
Newly Diagnosed ◽  
Hydroxyvitamin D ◽  
Left Ventricle Hypertrophy ◽  
25 Hydroxyvitamin D ◽  
Ventricle Hypertrophy

scholarly journals P2856Predictors of survival in hypertensive patients with left ventricle hypertrophy

2018 ◽  
Vol 39 (suppl_1) ◽  
Author(s):  
B Guzik ◽  
L McCallum ◽  
K Zmudka ◽  
A Jardine ◽  
T J Guzik ◽  
...  
Keyword(s):  
Left Ventricle ◽  
Hypertensive Patients ◽  
Left Ventricle Hypertrophy ◽  
Ventricle Hypertrophy

scholarly journals Effect of fosinopril on progression of the asymptomatic carotid atherosclerosis and left ventricular hypertrophy in hypertensive patients

2006 ◽  
Vol 134 (3-4) ◽  
pp. 106-113 ◽  
Author(s):  
Ivan Tasic ◽  
Dragan Mijalkovic ◽  
Dragan Djordjevic ◽  
Branko Lovic ◽  
Dimitrije Jankovic ◽  
...  
Keyword(s):  
Left Ventricle ◽  
Ace Inhibitor ◽  
Intima Media Thickness ◽  
Left Ventricle Mass ◽  
Hypertensive Patients ◽  
Left Ventricle Hypertrophy ◽  
Group A ◽  
The Common ◽  
Group B ◽  
Ventricle Hypertrophy

INTRODUCTION The cardiovascular changes (vascular structure changes, hypertrophy of the left ventricle) contribute to both the increased cardiovascular morbidity and the mortality of essential hypertension. Therefore, modern treatment strategies should not only target blood pressure (BP) reduction but also normalize cardiovascular structure and function. OBJECTIVE Aim of the study was to determine the effect of the ACE inhibitor Fosinopril on the Intima-media thickness of the common carotid artery and on the left ventricle mass after 9-month treatment of hypertensive patients. METHOD The study included 40 patients with the arterial hypertension and the left ventricle hypertrophy verified by echocardiography. The patients were randomized on A) ACE-inhibitor - Fosinopril and 6) without ACE inhibitor - atenolol, and they were followed up 9 months. The groups were not different by age, sex, and metabolic status. Color Duplex ultrasonography of the carotid arteries was performed by Acuson Sequia C236 with high-frequency linear probe of 8 MHz. The Intima-media thickness of the common carotids on the left and the right was measured in diastole at 1.5. cm from the highest point of bifurcation under maximal magnification. Using the same device, the left ventricle mass and other parameters of the left ventricle were determined in M-mode and by means of 2D image. RESULTS After 9 months, BP In both groups Was reduced In similar range (group A: systolic BP from 158 to 137 mmHg, and diastolic BP from 94 to 85 mmHg, and group B; systolic BP from 164 to 137 mmHg, and diastolic BP from 87 to 84 mmHg). The thickness of the intimomedial complex in patients using Fosinopril was decreased by 0.0278 ? 0.03 mm, while in the group of patients that did not use the ACE-inhibitor, it was increased by 0.078 ?0.13 mm. The left ventricle mass in patients using Fosinopril was decreased by 5 grams (312 ? 72 g vs. 307 ? 77 g), while in group B patients, it was increased by 15 grams (323 ? 79 g vs. 328 ? 58 g. Diastolic function expressed through relation E/A was improved minimally in the group A, while it worsened by 0.1 in the group B. After 9 months, serious cardiovascular events were recorded (one infarction of myocardium and one hospitalization due to the unstable angina pectoris) in two patients of the group A, while four patients of the group B. had serious CV events (1 cerebrovascular stroke and 3 hospitalizations due to unstable angina pectoris). CONCLUSION The results of our study showed that the application of Fosinopril in patients with the arterial hypertension and the left ventricle hypertrophy could efficiently block further progression of the intima-medial thickness of the common carotid artery, reduce the left ventricle mass, and improve. diastolic function of the left ventricle.

scholarly journals Compelling therapy of LVH: straight (and not-so-straight) inferences from evidence

2019 ◽  
Vol 25 (1) ◽  
Author(s):  
Ravi Tejraj Mehta ◽  
Anil Pareek ◽  
Shruti Dharmadhikari
Keyword(s):  
Left Ventricle ◽  
Review Of Literature ◽  
Left Ventricle Mass ◽  
Hypertensive Patients ◽  
Korean Society ◽  
Hypertension Guidelines ◽  
Left Ventricle Hypertrophy ◽  
Paradoxical Finding ◽  
Beneficial Action ◽  
Ventricle Hypertrophy

AbstractWe have read with interest the Korean Society of Hypertension guidelines for the management of hypertension and congratulate the Society for an extensive review of literature while drafting the guidelines. The guidelines indicate preferring ACE-I and CCB over diuretics in patients with left ventricle hypertrophy. However, in landmark head-to-head comparison trials, the thiazide-like diuretic chlorthalidone has been shown to be superior to ACE-I and CCB in decreasing left ventricle mass and preventing heart failure in hypertensive patients. Also, we put forth the paradoxical finding that mere regression of LVH may not always translate into reduction in risk of HF; and that the pleiotropic effects of chlorthalidone may be the explanation behind its beneficial action in HF.

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