Increased gamma-glutamyl transferase level is associated with absence of coronary collateral vessels in patients with acute coronary syndrome: an observational study

2012 ◽  
Author(s):  
Mustafa Duran ◽  
Ozgur Gunebakmaz ◽  
Onur Kadir Uysal ◽  
Ahmet Celik ◽  
Mikail Yarlioglues ◽  
...  
Keyword(s):  
Acute Coronary Syndrome ◽  
Observational Study ◽  
Gamma Glutamyl Transferase ◽  
Gamma Glutamyl ◽  
Coronary Syndrome ◽  
Coronary Collateral ◽  
Collateral Vessels ◽  
Glutamyl Transferase

STUDY ON EVALUATION OF SERUM GAMMA-GLUTAMYL TRANSFERASE (GGT) LEVELS IN ACUTE CORONARY SYNDROME

2021 ◽  
pp. 39-40
Author(s):  
Avtar Singh Dhanju ◽  
Deepshikha Singla ◽  
Pashaura Singh ◽  
Ajay Chhabra ◽  
Sukhraj Kaur
Keyword(s):  
Acute Coronary Syndrome ◽  
Cross Sectional Study ◽  
Gamma Glutamyl Transferase ◽  
Cross Sectional ◽  
Gamma Glutamyl ◽  
Coronary Syndrome ◽  
Healthy Control ◽  
Group A ◽  
Group B ◽  
Glutamyl Transferase

Aim: The present study was undertaken with the aim to evaluate serum Gamma Glutamyl Transferase (GGT) levels in patients of acute coronary syndrome. Methodology: This cross-sectional study was conducted on 50 cases with acute coronary syndrome (Group A) and 50 healthy control subjects (Group B) meeting inclusion and exclusion criteria. Results: There is signicant rise in serum GGT levels in patients presenting with ACS in Group A as compared to Group B. Conclusion: Higher levels of GGT in ACS patients with risk factors such as hypertension, dyslipidemia and smoking may serve as biomarker to predict the occurrence of ACS.

Serum gamma-glutamyl transferase activity: new high-risk criteria in acute coronary syndrome patients?

2008 ◽  
Vol 19 (7) ◽  
pp. 489-495 ◽  
Author(s):  
Taner Ulus ◽  
Aylin Yildirir ◽  
Leyla Elif Sade ◽  
Ahmet Temiz ◽  
Ezgi Polat ◽  
...  
Keyword(s):  
Acute Coronary Syndrome ◽  
High Risk ◽  
Transferase Activity ◽  
Gamma Glutamyl Transferase ◽  
Gamma Glutamyl ◽  
Coronary Syndrome ◽  
Risk Criteria ◽  
Glutamyl Transferase

scholarly journals A Descriptive Study on Levels of Serum Bilirubin and GammaGlutamyl-Transferase (GGT) in Patients of Acute Coronary Syndrome Visiting a Tertiary Care Hospital of Southern Bihar

2020 ◽  
Vol 7 (50) ◽  
pp. 3001-3005
Author(s):  
Nitin Kumar Gupta ◽  
Abhilasha Singh ◽  
Rajan Goyal ◽  
Abhishek Kamendu
Keyword(s):  
Acute Coronary Syndrome ◽  
Total Cholesterol ◽  
Cholesterol Level ◽  
Total Bilirubin ◽  
Serum Bilirubin ◽  
Total Cholesterol Level ◽  
Serum Triglyceride ◽  
Gamma Glutamyl Transferase ◽  
Coronary Syndrome ◽  
Glutamyl Transferase

BACKGROUND Most cases of ACS (Acute Coronary Syndrome) are caused by rupture of an atherosclerotic plaque in a coronary artery, resulting in the formation of a thrombus. Atherosclerosis results from an over balance between radical generating, compared with radical scavenging systems, a condition called oxidative stress. Bilirubin had some role in mechanism of ACS. We wanted to evaluate the association between raised total bilirubin level and GGT levels with different subsets of acute coronary syndrome. METHODS The present descriptive cross-sectional study was conducted at Narayan Medical College and Hospital from July 2019 to April 2020. Total serum bilirubin was measured in the laboratory by spectrophotometry method. Gamma glutamyl transferase levels were measured in all the patients using a standardized photometric method. RESULTS In our study the mean value of triglyceride is 159.86 ± 42.36 with range 60 - 246. Total bilirubin 2.23 ± 0.827, with range 1 - 4. The value of gamma glutaraldehyde was 56.67 ± 26.48 with range 22 - 104. On studying the correlation of serum bilirubin and serum triglyceride in our study subjects, we found very mild correlation with an R square of 0.028. On finding correlation of GGT and serum triglyceride in our study subjects. We found almost no correlation with R square 0. When we do multivariate analysis of effect of serum bilirubin, GGT on total cholesterol level we found that there is very mild correlation with R square 0.031. CONCLUSIONS In our study there was very mild correlation between serum bilirubin and gamma glutamyl transferase with marker of acute coronary syndrome such as serum triglyceride level and total cholesterol level but the association was significant. KEYWORDS Acute Coronary Syndrome, Triglyceride, Bilirubin, Gamma Glutaraldehyde

scholarly journals Association between Gamma-Glutamyl Transferase and Coronary Atherosclerotic Plaque Vulnerability: An Optical Coherence Tomography Study

2019 ◽  
Vol 2019 ◽  
pp. 1-11 ◽  
Author(s):  
Jun Wang ◽  
Xing Li ◽  
Jun Pu ◽  
Siyu Jin ◽  
Lu Jia ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Atherosclerotic Plaque ◽  
Apolipoprotein A1 ◽  
Gamma Glutamyl Transferase ◽  
Optical Coherence ◽  
Plaque Vulnerability ◽  
Gamma Glutamyl ◽  
Coronary Syndrome ◽  
Coronary Atherosclerotic Plaque ◽  
Glutamyl Transferase

Background. Gamma-glutamyl transferase (GGT) has been detected in coronary plaques. However, the association between serum GGT levels and coronary atherosclerotic plaque vulnerability in patients with coronary artery disease (CAD) as detected by optical coherence tomography (OCT) has not been investigated.Methods. We performed a retrospective study of consecutively enrolled CAD patients undergoing preintervention OCT examination during coronary angiography. Plaque vulnerability was defined as the presence of ruptured plaques or thin-cap fibroatheroma (TCFA) upon OCT. The association between serum GGT levels and coronary plaque vulnerability was evaluated using multivariate logistic regression analysis.Results. A total of 142 patients were included in our analysis. OCT examination detected ruptured plaques in 16 patients, nonruptured plaques with TCFA in 17 patients, and nonruptured plaques and non-TCFA in 109 patients. Univariate analyses showed that gender, diabetes, Apolipoprotein A1 (ApoA1) and high-density lipoprotein cholesterol (HDL-c), and diagnosis of acute coronary syndrome (ACS) were associated with plaque vulnerability (P all < 0.05). Patients grouped according to serum GGT tertiles did not differ statistically in baseline characteristics or OCT findings. Results of multivariate logistic analyses showed that diabetes and diagnosis of ACS were associated with plaque rupture and TCFA (P < 0.05).Conclusions. GGT serum levels were not associated with OCT detected coronary vulnerability in our cohort of CAD patient.

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