Elevated pentraxin-3 levels are related to blood pressure levels in hypertensive patients: an observational study

Author(s):  
Adem Parlak ◽  
Umit Aydogan ◽  
Atila Iyisoy ◽  
Mehmet Aytug Dikililer ◽  
Altug Kut ◽  
...  
2012 ◽  
Vol 35 (6) ◽  
pp. 624-632 ◽  
Author(s):  
Saide Aytekin ◽  
Sema Guneri ◽  
Nese Cam ◽  
Ali Aydinlar ◽  
Guliz Kozdag ◽  
...  

Author(s):  
Disha Bhatero ◽  
Punam Sawarkar ◽  
Vaishnavi Paraskar ◽  
Gaurav Sawarkar

Background: In 2000, 26.4% people of the society were suffering hypertension in the globe and around 29.2% are considered to have hypertension till 2025. Coronary Heart Disease, Stroke and other vascular disorders are the adverse effects of hypertension. Hypertension is taxonomically adjacent to UchchaRakta Tapa in Ayurveda. Prakrutiis the morphological, physiological, and psychological basic traits, manifested in the intrauterine life and is said to be unchangeable throughout life. Objectives: The present study aims to observe the Prevalence of Essential Hypertension in different types of Prakruti to differentiate Systolic blood pressure and Diastolic blood pressure according to various Prakruti in the population of Wardha city and contribute to knowledge in this population regarding Essential Hypertension and its relation with Prakruti. Materials and Methods: Wardha. Data collected in from the hypertensive patients in Wardha district by personal interviews based on the Prakruti Questionnaires. Results: The results will be concluded on the basis of observations drawn from the collected information.


2021 ◽  
Vol 27 (1) ◽  
Author(s):  
Il Suk Sohn ◽  
Sang-Hyun Ihm ◽  
Gee Hee Kim ◽  
Sang Min Park ◽  
Bum-Kee Hong ◽  
...  

Abstract Background In this prospective, multicenter, non-comparative observational study, the effectiveness and safety of the triple single-pill combination (SPC) of olmesartan/amlodipine/hydrochlorothiazide (OM/AML/HCTZ) were evaluated in a real clinical practice setting in Korean patients with essential hypertension. Methods A total of 3752 patients were enrolled and followed for 12 months after administration of OM/AML/HCTZ. Primary endpoint was change from baseline to month 6 in the mean systolic blood pressure (SBP). Secondary endpoints included changes from baseline in the mean SBP at month 3, 9, 12 and the mean diastolic blood pressure (DBP) at month 3, 6, 9, 12; changes in the mean SBP/DBP according to age and underlying risk factors; and blood pressure control rate (%) at different time points. Adherence to and satisfaction with OM/AML/HCTZ treatment among patients and physicians were assessed by medication possession ratio (MPR) and numeric rating scale, respectively, as exploratory endpoints. Safety was evaluated by the incidence and severity of adverse events (AEs) as well as the discontinuation rate due to AEs. Results OM/AML/HCTZ administration led to significant reductions in the mean SBP/DBP by 11.5/6.6, 12.3/7.0, 12.3/7.2, and 12.8/7.4 mmHg from baseline to month 3, 6, 9 and 12, respectively (P < 0.0001). The BP reductions were maintained throughout the 1-year observation period in all patients with different age groups and risk factors (diabetes mellitus, cardiovascular disease, and renal disease). The BP control rate (%) of < 140/90 mmHg was 65.9, 67.9, 68.9, and 70.6% at month 3, 6, 9, and 12, respectively. The mean MPR during the observation period was 0.96. The safety results were consistent with the previously reported safety profile of OM/AML/HCTZ. Conclusions Treatment with the triple SPC of OM/AML/HCTZ demonstrated significant effectiveness in reducing SBP/DBP and achieving target BP control with high adherence over the 1-year observation period in Korean hypertensive patients and was well-tolerated. Trial registration CRIS, KCT0002196, Registered 3 May 2016.


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