Relationship between heart-type fatty acid-binding protein levels and coronary artery disease in exercise stress testing: an observational study

2011 ◽  
Author(s):  
Hatem Ari ◽  
Mehmet Tokac ◽  
Yusuf Alihanoglu ◽  
Aysel Kiyici ◽  
Mehmet Kayrak ◽  
...  
Keyword(s):  
Coronary Artery Disease ◽  
Fatty Acid ◽  
Coronary Artery ◽  
Stress Testing ◽  
Fatty Acid Binding Protein ◽  
Exercise Stress ◽  
Fatty Acid Binding ◽  
Protein Levels ◽  
Acid Binding Protein ◽  
Artery Disease

Heart type fatty acid binding protein in relation to pharmacologic scintigraphy in coronary artery disease

2012 ◽  
Vol 50 (2) ◽  
Author(s):  
Eftihia Sbarouni ◽  
Panagiota Georgiadou ◽  
Maria Koutelou ◽  
Mihas Constantinos ◽  
Antigoni Chaidaroglou ◽  
...  
Keyword(s):  
Coronary Artery Disease ◽  
Fatty Acid ◽  
Coronary Artery ◽  
Stress Testing ◽  
Fatty Acid Binding Protein ◽  
Binding Protein ◽  
Serum Levels ◽  
Fatty Acid Binding ◽  
Acid Binding Protein ◽  
Artery Disease

AbstractHeart-type fatty acid-binding protein (H-FABP) is a marker of myocardial necrosis, but whether it increases during myocardial ischemia is not known. This study investigated whether serum levels of H-FABP change during adenosine stress testing and nuclear imaging in patients with stable coronary artery disease.Thirty stable patients with established coronary artery disease on their medications were studied. Sampling was performed before the stress test, at the end of adenosine infusion, as well as 1, 2 and 3 h after the completion of the infusion.No difference in H-FABP serum levels were found at the five pre-specified time points in the overall group (p=0.99); furthermore, there was no significant difference regardless of the test result – positive (p=1) or negative (p=0.98).It is concluded that H-FABP does not change significantly during pharmacologic stress testing in patients with known coronary artery disease and there is no difference whether there is inducible ischemia or not.

Concentrations of circulating adiponectin and adipocyte-fatty acid binding protein in patients with three-vessel coronary artery disease: a comparison with coronary lesion complexity as characterized by syntax score

2017 ◽  
Vol 43 (1) ◽  
pp. 30-39
Author(s):  
Cihan Coşkun ◽  
Alper Gümüş ◽  
Hümeyra Öztürk Emre ◽  
Birol Özkan ◽  
Selçuk Pala ◽  
...  
Keyword(s):  
Coronary Artery Disease ◽  
Fatty Acid ◽  
Coronary Artery ◽  
Fatty Acid Binding Protein ◽  
Syntax Score ◽  
Fatty Acid Binding ◽  
Coronary Lesion ◽  
Acid Binding Protein ◽  
Artery Disease ◽  
Stable Cad

AbstractObjective:In this study, we investigated the correlation between coronary lesion complexity as characterized by syntax score (SS) with circulating adiponectin and adipocyte-fatty acid binding protein (A-FABP4) concentrations in the presence of stable coronary artery disease affecting three coronary vessels (three-vessel stable CAD).Methods:The study groups consisted of 41 control subjects (28 males and 13 females, non-CAD group) and 115 affected subjects (79 males and 36 females, three-vessel stable CAD group). We divided into tertiles the three-vessel stable CAD group according to SS and estimated circulating concentrations of adiponectin and A-FABP4.Results:We did not find any correlation between the coronary lesion complexity with either the adiponectin and/or A-FABP4. We found lower the A-FABP4 of the non-CAD group than those of the groups with three-vessel stable CAD (p<0.001). Adiponectin were lower in DM subjects (p<0.05 for each group); though A-FABP4 were found to be higher (p<0.05 for each group) according to non-DM subjects in intra-group comparisons.Conclusion:Adiponectin is not a suitable parameter for demonstrating the existence of CAD or predicting coronary lesion complexity. A-FABP4 is more useful for the proof of the presence of CAD but A-FABP4 are not correlated with the severity of CAD.

scholarly journals Association of increased plasma adipocyte fatty acid-binding protein with coronary artery disease in non-elderly men

2011 ◽  
Vol 10 (1) ◽  
pp. 44 ◽  
Author(s):  
Masayuki Doi ◽  
Toru Miyoshi ◽  
Satoshi Hirohata ◽  
Kazufumi Nakamura ◽  
Shinichi Usui ◽  
...  
Keyword(s):  
Coronary Artery Disease ◽  
Fatty Acid ◽  
Coronary Artery ◽  
Fatty Acid Binding Protein ◽  
Binding Protein ◽  
Elderly Men ◽  
Fatty Acid Binding ◽  
Acid Binding Protein ◽  
Artery Disease
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