scholarly journals Evaluation of congenital heart diseases and thyroid abnormalities in children with Down syndrome

2010 ◽  
Vol 10 (5) ◽  
pp. 440-445 ◽  
Author(s):  
Ercan Mihci ◽  
Gayaz Akcurin ◽  
Erdal Eren ◽  
Fırat Kardelen ◽  
Sema Akcurin ◽  
...  
Keyword(s):  
Down Syndrome ◽  
Congenital Heart ◽  
Heart Diseases ◽  
Congenital Heart Diseases ◽  
Children With Down Syndrome ◽  
Thyroid Abnormalities

scholarly journals Medical problems in children with Down syndrome

2018 ◽  
Vol 5 (5) ◽  
pp. 1290
Author(s):  
Suresh S. Vadakedom ◽  
Deepa K. Krishnan ◽  
Darly Saramma Mammen ◽  
Bindhu K. P. ◽  
Jiji Mary Antony
Keyword(s):  
Down Syndrome ◽  
Congenital Heart ◽  
Respiratory Infections ◽  
Heart Diseases ◽  
Genetic Disorder ◽  
Endocrine System ◽  
Congenital Heart Diseases ◽  
Medical Problems ◽  
Children With Down Syndrome ◽  
The Common

Background: Down syndrome (DS) is a major cause of mental retardation of prenatal origin and has several associated co-morbidities involving cardiovascular system, respiratory, endocrine system, hematological, gastrointestinal, musculoskeletal, eye and ear defects, immunological changes and neurological system. This study was conducted to identify the common medical problems in children with Down syndrome and the morbidity associated with these conditions. The objective of the present study was to find out the occurrence of different medical problems in children with DS.Methods: 42 children with a phenotype of Down syndrome in the age group of 0-12 years attending the outpatient, inpatient and Down syndrome Clinic of the Institute of Child Health, Kottayam during the study period were included in the study by purposive sampling. Demographic details were entered, and Pediatric Clinical Examination was performed by the investigator himself to identify the medical problems. Old medical reports were reviewed, and data entered into a proforma and statistically analysed.Results: Out of the 42 children with DS, 22 were males. 15 (35.7%) were less than 1 year, 20 (48.3%) children 1-5 years and 7 (16.1%) children 5-12 years of age. Mean age of the study group was 1.78±0.51 years. Mean age of their mothers at the time of conception was 30.6±5.8 years. 26 (57%) children with Down syndrome had a medical problem during the neonatal period which required hospitalization. Almost all systems are affected and craniofacial features, developmental delay and hypotonia were universal. Various forms of congenital heart diseases were observed in 67% and hypothyroidism in 23.8%.Conclusions: Down syndrome is a common genetic disorder with multisystem involvement. Congenital heart diseases, hypothyroidism and recurrent respiratory infections were the common medical problems identified in this study.

scholarly journals Pattern of Congenital Heart Diseases and Treatment Options in a Bangladeshi Centre: Analysis of 6914 cases from Non-invasive Cardiac Laboratory

2017 ◽  
Vol 9 (2) ◽  
pp. 97-105
Author(s):  
Nurun Nahar Fatema
Keyword(s):  
Down Syndrome ◽  
Chromosomal Abnormality ◽  
Congenital Heart ◽  
Septal Defect ◽  
Heart Diseases ◽  
Ductus Arteriosus ◽  
Treatment Options ◽  
Atrioventricular Septal Defect ◽  
Congenital Heart Diseases ◽  
Transposition Of Great Arteries

Background: Echocardiography is the most sensitive tool to diagnose congenital heart diseases efficiently. It can be repeated as many times as required to see the progress, outcome of treatment and complications. Echocardiography laboratory can give a scenario of pattern of congenital heart diseases existing in Bangladesh as well as natural history of the cases and treatment options offered.Methods: It is a retrospective review of database of echocardiography patient from pediatric noninvasive laboratory of a cardiac hospital from January 2012 to December 2012.Results: Out of 6914 cases 55.73% were male and 44.27% female. Neonates include 8.48%, 36.62% Down Syndrome were infant, 34.02% were under 5 years, 17.97% were children and adolescents and 2.96% were adults. Normal Echocardiography finding was found in 17.28% cases. Ventricular septal defect (VSD) was found in 18.60% cases, Atrial septal defects (ASD) in 15.41% cases, Patent ductus arteriosus (PDA) in 8.59% cases, Atrioventricular septal defect (AVSD) in 1.97% cases, Tetralogy of Fallot (TOF) in 4.79% cases and Transposition of great arteries (TGA) in 2.26% cases. Down syndrome was the commonest chromosomal abnormality seen in 2.4% cases.Conclusion: This study shows that VSD is the commonest congenital heart lesions in our country followed by ASD. Down syndrome was the commonest chromosomal abnormality seen in 2.4% cases.Cardiovasc. j. 2017; 9(2): 97-105

scholarly journals Congenital Heart Diseases in Down Syndrome Children at Albala Area, Saudi Arabia

2017 ◽  
Vol 03 (02) ◽  
Author(s):  
Almawazini AM ◽  
Ali A Sharkawy ◽  
Osama Mohammed Eldadah ◽  
Yahya Ali Sumaily ◽  
Tarig Yassin Alamery
Keyword(s):  
Saudi Arabia ◽  
Down Syndrome ◽  
Congenital Heart ◽  
Heart Diseases ◽  
Congenital Heart Diseases

scholarly journals The spectrum of congenital heart diseases in down syndrome. A retrospective study from Northwest Saudi Arabia

2016 ◽  
Vol 37 (7) ◽  
pp. 767-772 ◽  
Author(s):  
Mohamed Morsy ◽  
Osama Algrigri ◽  
Sherif Salem ◽  
Mostafa Abosedera ◽  
Ashraf Abutaleb ◽  
...  
Keyword(s):  
Saudi Arabia ◽  
Down Syndrome ◽  
Retrospective Study ◽  
Congenital Heart ◽  
Heart Diseases ◽  
Congenital Heart Diseases

scholarly journals Study of congenital heart diseases in patients with Down syndrome in Algeria

2017 ◽  
Vol 23 (9) ◽  
pp. 632-636 ◽  
Author(s):  
Khaira Boussouf ◽  
Zoubida Zaida ◽  
Mounira Amrane ◽  
Naima Hammoudi ◽  
Malika Mebarki ◽  
...  
Keyword(s):  
Down Syndrome ◽  
Congenital Heart ◽  
Heart Diseases ◽  
Congenital Heart Diseases

scholarly journals Pattern of Congenital Heart Diseases in Children with Congenital Malformations: An Echocardiographic study from a Tertiary Health facility in Sokoto, Nigeria

2021 ◽  
Vol 4 (7) ◽  
pp. 01-06
Author(s):  
Isezuo KO
Keyword(s):  
Down Syndrome ◽  
Congenital Malformations ◽  
Congenital Heart ◽  
Septal Defect ◽  
Heart Diseases ◽  
Statistical Significance ◽  
Congenital Heart Diseases ◽  
Cardiac Murmur ◽  
Cross Sectional ◽  
Ocular Abnormalities

Background: Children with congenital malformations (CM) may have congenital heart diseases (CHDs) which may be initially asymptomatic. These need to be recognised and managed early in order to reduce unnecessary morbidity in affected patients. We report the pattern of CHDs in children with congenital malformations who had echocardiography over a one year period in UDUTH, Sokoto. Materials and Methods: A cross-sectional study carried out in the Paediatric Cardiology Unit from 1st January to 31st December 2019. Children presenting with CM were recruited and had echocardiagraphic screening for CHDs. Data were analysed with SPSS 23 version. Statistical significance was taken at p < 0.05. Results: 81 children were seen with CM, comprising 42 females and 39 males (M:F=0.93:1); age range of 2 days to 13 years. Most frequent malformationswere anorectal malformations (ARM) in 28 (34.6%), Down syndrome in 17 (21.0%), multiple CM 10 (8.1%) and ocular abnormalities in 4 (4.9%). Thirty two (39.5%) of the patients with CM were diagnosed with CHD, out of which 24 (29.6%) had cardiac murmur. Most frequent CHD was atrioventricular septal defect in 9 (28.1%) followed by ventricular septal defect in 8 (25.0%) and patent arterial duct in 4 (12.5%). CHDs were found in all (100%) those with ocular abnormalities, in 76.5% of Down syndrome and in 14.3% of patients with ARM. Presence of murmur was significantly associated with CHD (χ2=18.0; p=0.001; OR=8.2; 95% C.1=2.8 – 24.1). Conclusion: Congenital malformations, particularly Down syndrome and ocular abnormalities, are significantly associated with CHDs. Cardiac murmurs were suggestive of CHD in children with congenital malformations.

Sign in / Sign up

Export Citation Format

Share Document