scholarly journals ASSESSING THE IMPACT OF LUPUS NEPHRITIS IN A CHILDHOOD-ONSET SYSTEMIC LUPUS ERYTHEMATOSUS COHORT

2019 ◽  
Author(s):  
ANA PAULA SAKAMOTO ◽  
LIANA SOIDO TEIXEIRA E SILVA ◽  
ANA MARIA LOROÑO TERRAZAS ◽  
CLÁUDIO ARNALDO LEN ◽  
CLOVIS ARTUR ALMEIDA DA SILVA ◽  
...  
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Lupus Nephritis ◽  
Lupus Erythematosus ◽  
Childhood Onset ◽  
Systemic Lupus ◽  
The Impact ◽  
Onset Systemic Lupus Erythematosus

scholarly journals Validation of the Lupus Nephritis Clinical Indices in Childhood-Onset Systemic Lupus Erythematosus

2016 ◽  
Vol 68 (2) ◽  
pp. 195-202 ◽  
Author(s):  
Rina Mina ◽  
Khalid Abulaban ◽  
Marisa S. Klein-Gitelman ◽  
Barbara A. Eberhard ◽  
Stacy P. Ardoin ◽  
...  
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Lupus Nephritis ◽  
Lupus Erythematosus ◽  
Childhood Onset ◽  
Systemic Lupus ◽  
Clinical Indices ◽  
Onset Systemic Lupus Erythematosus

scholarly journals Proliferative nephritis in childhood-onset systemic lupus erythematosus: current therapeutic approaches and future perspectives

F1000Research ◽  
2015 ◽  
Vol 4 ◽  
pp. 128
Author(s):  
Dawn M. Wahezi
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Lupus Erythematosus ◽  
Renal Involvement ◽  
Childhood Onset ◽  
Systemic Lupus ◽  
Proliferative Lupus Nephritis ◽  
Stage Renal Disease ◽  
End Stage ◽  
The Impact ◽  
Onset Systemic Lupus Erythematosus

Renal involvement occurs in 50-75% of children with childhood-onset systemic lupus erythematosus (cSLE). Proliferative lupus nephritis (LN) represents the most common pattern of renal involvement in cSLE. Despite aggressive treatment, progression to end stage renal disease can occur in up to 5-10% of children. Over the last 2 decades, tremendous advancements have been made in the treatment of pediatric LN. Special considerations in children need to address the impact of disease and therapy on both physical and psychological growth and development. This review will focus on pivotal clinical trials in the treatment of proliferative LN, with a focus on pediatric data when available.

Sign in / Sign up

Export Citation Format

Share Document