scholarly journals SYSTEMIC LUPUS ERYTHEMATOSUS VERSUS BEHÇET’S DISEASE: A DIAGNOSTIC DILEMMA

2019 ◽  
Author(s):  
LAURA ALÍCIA MORAIS LIMA OLIVEIRA ◽  
HERON ALVES VALE ◽  
BRENO VINÍCIUS DIAS DE SOUZA ◽  
ANA OLÍVIA DANTAS ◽  
LAUANDA ÊNIA MEDEIROS ROCHA ◽  
...  
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Behçet’S Disease ◽  
Lupus Erythematosus ◽  
Behcet’S Disease ◽  
Behçet's Disease ◽  
Systemic Lupus ◽  
Diagnostic Dilemma ◽  
Behcet's Disease

scholarly journals Ischemic Retinal Vasculitis and Its Management

2014 ◽  
Vol 2014 ◽  
pp. 1-13 ◽  
Author(s):  
Lazha Talat ◽  
Sue Lightman ◽  
Oren Tomkins-Netzer
Keyword(s):  
Multiple Sclerosis ◽  
Systemic Lupus Erythematosus ◽  
Lupus Erythematosus ◽  
Laser Photocoagulation ◽  
Behcet’S Disease ◽  
Behçet's Disease ◽  
Retinal Vasculitis ◽  
Retinal Ischemia ◽  
Systemic Lupus ◽  
Behcet's Disease

Ischemic retinal vasculitis is an inflammation of retinal blood vessels associated with vascular occlusion and subsequent retinal hypoperfusion. It can cause visual loss secondary to macular ischemia, macular edema, and neovascularization leading to vitreous hemorrhage, fibrovascular proliferation, and tractional retinal detachment. Ischemic retinal vasculitis can be idiopathic or secondary to systemic disease such as in Behçet’s disease, sarcoidosis, tuberculosis, multiple sclerosis, and systemic lupus erythematosus. Corticosteroids with or without immunosuppressive medication are the mainstay treatment in retinal vasculitis together with laser photocoagulation of retinal ischemic areas. Intravitreal injections of bevacizumab are used to treat neovascularization secondary to systemic lupus erythematosus but should be timed with retinal laser photocoagulation to prevent further progression of retinal ischemia. Antitumor necrosis factor agents have shown promising results in controlling refractory retinal vasculitis excluding multiple sclerosis. Interferon has been useful to control inflammation and induce neovascular regression in retinal vasculitis secondary to Behçet’s disease and multiple sclerosis. The long term effect of these management strategies in preventing the progression of retinal ischemia and preserving vision is not well understood and needs to be further studied.

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