scholarly journals Granulomatosis with polyangiitis in a patient and coincident mucoepidermoid carcinoma of the lung: case report

2019 ◽  
Vol 3 (3) ◽  
pp. 149
Author(s):  
Tuğba TOYRAN ◽  
Emine KILIÇ BAĞIR ◽  
Alper AVCI ◽  
Derya GÜMÜRDÜLÜ
Keyword(s):  
Case Report ◽  
Mucoepidermoid Carcinoma ◽  
Granulomatosis With Polyangiitis

scholarly journals AB0858 SUCCESSFUL TERM PREGNANCY IN A PATIENT WITH GRANULOMATOSIS WITH POLYANGIITIS AFTER UNDERGOING RITUXIMAB THERAPY - CASE REPORT

2021 ◽  
Vol 80 (Suppl 1) ◽  
pp. 1452.2-1453
Author(s):  
O. Sirenko ◽  
O. Kuryata ◽  
T. Lysunets ◽  
A. Legkobyt ◽  
H. Mostova
Keyword(s):  
Case Report ◽  
Granulomatosis With Polyangiitis ◽  
Disease Onset ◽  
Biological Agents ◽  
Term Pregnancy ◽  
Aseptic Necrosis ◽  
Azathioprine Therapy ◽  
Disease Remission ◽  
Obstetric Medicine ◽  
Patient Reported

Background:Granulomatosis with polyangiitis (GWP) is a relatively rare disease with the lack of experience in the management of pregnancy currently. Potentially negative factors of pregnancy prognosis are both disease-related and teratogenic effects of specific vasculitis therapy [1].Objectives:To describe a clinical case of Successful term pregnancy in a patient with Granulomatosis with polyangiitis after undergoing rituximab therapy.Methods:19 years-old woman was admitted to the rheumatology department of Clinical Regional Hospital After Mechnicov in 2013 with the debut of Granulomatosis with polyangiitis. Her disease course included recurrent rhinitis and sinusitis, Granulomatosis of the eye orbits. Positive ANCA titers were present in the disease onset. In the preceding 7 years she had been treated with corticosteroids, cyclophospan (discontinuated in 2017 because of lack of efficiency), than azathioprine. Aseptic necrosis of the both femoral head was estimated on fifth disease year. In 2018 azathioprine therapy had been discontinued owing to the disease progression and biological agents were prescribed – rituximab with positive effect. The disease remission was achived by rituximab therapy, the patient was warned about the need for contraception. The last dose of rituximab was introduced in February 2020. However, in March 2020, the patient reported pregnancy and therapy was discontinued. At the onset of pregnancy she was treated with 6 mg oral methylprednisolone. Daily and this dose was stable till all pregnancy period. Fetal growth assessment, congenital abnormalities screening test, and laboratory tests for gestational diabetes and preeclampsia were unremarkable during all gestational trimesters. The ANCA titers remained negative and renal function was normal and there was no flare during all pregnancy period.Results:At 38 weeks’ gestation a spontataneous labor started without induction. A 3270-g healthy boy delivered with APGAR score of 9 at 1 minute and 5 minutes. Postpartum the disease remained in remission, and the patient was maintained on corticosteroids. The infant was healthy, with normal development.Conclusion:Thus, the use of biological agents therapy in patients with GWP shows possible ways to safe reproductive potential with disease remission achievement.References:[1]Daher A, Sauvetre G, Girszyn N, Verspyck E, Levesque H, Le Besnerais M. Granulomatosis with polyangiitis and pregnancy: A case report and review of the literature. Obstetric Medicine. 2020;13(2):76-82. doi:10.1177/1753495X18822581Disclosure of Interests:None declared

scholarly journals Mucoepidermoid carcinoma of the retromolar trigone in an elderly female: A case report

2021 ◽  
pp. 102487
Author(s):  
Rachid Aloua ◽  
Ulrich Opoko ◽  
Ouassime Kerdoud ◽  
Zahra Hmoura ◽  
Faiçal Slimani
Keyword(s):  
Case Report ◽  
Mucoepidermoid Carcinoma ◽  
Elderly Female ◽  
Retromolar Trigone

scholarly journals Mucoepidermoid Carcinoma of the Larynx: A Case Report.

1995 ◽  
Vol 46 (5) ◽  
pp. 433-436
Author(s):  
Shitau Hirata ◽  
Koji Yajin ◽  
Nobuharu Tagashira ◽  
Masanori Aoki ◽  
Chiharu Tamura
Keyword(s):  
Case Report ◽  
Mucoepidermoid Carcinoma ◽  
Carcinoma Of The Larynx
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