scholarly journals Phytochemical composition and in vitro antioxidant activity of methanolic and aqueous extracts of aerial part of Pentatropis nivalis(Asclepiadaceae)

2018 ◽  
Vol 10 (1) ◽  
pp. 68
Author(s):  
Nilesh P. Babre ◽  
T. Shivraj Gouda ◽  
Narayanswamy Lachmanan Gowrishankar

<p>The objective of present study was to evaluate preliminary phytoconstitutents and <em>invitro</em> antioxidant potential of <em>Pentatropis nivalis </em>(Asclepiadaceae). During the preliminary phytochemical analysis, methanolic and aqueous extracts of aerial part of <em>Pentatropis nivalis</em> was screened for the presence of phenolic, saponins, flavonoids, alkaloids, tannins and phytosterols. TLC of extracts were performed by using various solvent systems. Phytochemicals screening and TLC spots of MEPN and AEPN showed the presence of glycoside, steroids, terpenoids, phenolic, saponins, Methanolic extract showed better qualitative tests for presence of secondary metabolites than aqueous extract.The in-vitro antioxidant potential of extracts were evaluated by DPPH and FRAP, and both methods showed that the plant possesses good antioxidant activity.</p>

Author(s):  
Krishma M. Jadav ◽  
K. N. Ninge Gowda

Objective: Four different extracts of Araucaria columnaris (bark peel) and Cosmos sulphureus (flowers) were screened for their phytochemical composition, and free radical scavenging activities.Methods: DPPH method was used to test the antioxidant activity for extracts.Results: Among the different extracts tested, the methanol extract of both the plant species showed significant radical scavenging activities. Phytochemical analysis of the extracts revealed that the radical scavenging activities might be due to the presence of flavonoids, tannins and phenolic compounds.Conclusion: The results obtained suggest that Araucaria columnaris (bark peel) and Cosmos sulphureus(flowers) could be exploited in the treatment of various diseases like cancer, cardiovascular diseases and infection diseases.  


2020 ◽  
Vol 10 (2) ◽  
pp. 158-162 ◽  
Author(s):  
Humaira Yasmeen Gondal ◽  
Roshan Zamir ◽  
Muhammad Nisar ◽  
Muhammad Iqbal Choudhary

Background: The genus Verbascum is well documented for its antioxidant potential but Verbascum sinaiticum is comparatively less studied plant. The current study was carried out to search for antioxidant nutraceuticals from this species. Objective: To explore the antioxidant potential of Verbascum sinaiticum and to identify its active constituents. Methods: The methanolic extract of air-dried aerial part of the Verbascum sinaiticum was partitioned with hexane, chloroform and ethyl acetate. The water-soluble part of ethyl acetate afforded six phenylethanoid glycosides by repeated chromatography over Sephadex LH-20, silica gel and ODS columns. Antioxidant activity of solvent extracts and isolated constituents were evaluated by DPPH, ABTS and FRAP assays. Results: Six phenylethanoid glycosides was isolated and characterized as Verbascoside, Eukovoside, Martynoside, Jionoside D, Campneoside I and Campneoside II, from the most active fraction. Conclusion: Verbascum sinaiticum demonstrated prospective antioxidant activity. The watersoluble part of EtOAc (WSEAE) was found the most active extract whereas Verbascoside was identified as the most potent constituent. All isolated compounds exhibited significant antioxidant activity whereas their synergistic effect was found prominent in the parent fraction.


2020 ◽  
Vol 151 ◽  
pp. 112439
Author(s):  
Martha Gómez-Martínez ◽  
Juan A. Ascacio-Valdés ◽  
Adriana C. Flores-Gallegos ◽  
Jorge González-Domínguez ◽  
Susana Gómez-Martínez ◽  
...  

2012 ◽  
Vol 6 (1) ◽  
pp. 67 ◽  
Author(s):  
Mohd Mujeeb ◽  
Kamran Ashraf ◽  
Mohammad Aqil ◽  
Mohd Amir ◽  
Ahsanullah Khan ◽  
...  

2017 ◽  
Vol 17 (2) ◽  
pp. 151-160 ◽  
Author(s):  
Karima Belarbi ◽  
Fawzia Atik-Bekkara ◽  
Imad Abdelhamid El Haci ◽  
Ilhem Bensaid ◽  
Fawzia Beddou ◽  
...  

Pharmacologia ◽  
2016 ◽  
Vol 7 (4) ◽  
pp. 193-201 ◽  
Author(s):  
Joao Batista Teixeir Rocha ◽  
Gerlania de Oliveira Leite ◽  
Albys Ferrer Dubois ◽  
Rodrigo Lopes Seeger ◽  
Aline Augusti Boligon ◽  
...  

2021 ◽  
Vol 25 (03) ◽  
pp. 677-682
Author(s):  
Amara Javaid

The present study was conducted to evaluate the in vitro antioxidant activity of Ficus carica, commonly known as fig. Methanol and ethanol extracts of F. carica leaves were subjected to 2, 2-diphenyl-1-picryhydrazyl (DPPH) free radical scavenging activity assay where ascorbic acid being positive control had an IC50 value of 3.98±0.26 while methanol and ethanol fractions showed an IC50 of 101.76±1.12 and 93.12±1.17 respectively exhibiting their high antioxidant potential. DPPH assay was also performed on high performance liquid chromatography (HPLC) elutions. Most active antioxidant components in ethanol extract were eluted between 17–18 min, and those in methanol were eluted over 14–15 min and upon ultra-high performance liquid chromatography-mass spectrometery (Orbitrap Liquid Chromatography-Mass Spectrometry) were identified to be 13-Docosenamide, (Z)- for ethanol and ficusin for methanol fraction. Thus, it is concluded that these two components are most probable determinants of antioxidant potential of F. carica leaf extracts. © 2021 Friends Science Publishers


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