scholarly journals Ethnobotany and preliminary bioactivity investigation on hepatoprotective medicinal plants from the Mouhoun Region of Burkina Faso

2018 ◽  
Vol 10 (2) ◽  
pp. 73
Author(s):  
Jotham Yhi-pênê N'DO ◽  
André TIBIRI ◽  
Ernest Nogma SOMBIE ◽  
Tata Kadiatou TRAORE ◽  
Noufou OUEDRAOGO ◽  
...  
Keyword(s):  
Medicinal Plants ◽  
Burkina Faso ◽  
Phenolic Content ◽  
Antioxidant Properties ◽  
Cation Radical ◽  
Total Phenolic ◽  
Root Bark ◽  
Ethnobotanical Survey ◽  
Antioxidant Power ◽  
Phenolic Contents

<p>An ethnobotanical survey of medicinal plants used to treat hepatitis in the Mouhoun region of Burkina Faso was undertaken. The extracts of the most quoted species were then evaluated for their phytochemistry and their antioxidant activity</p><p>The anti-radical activity (by the method of the discoloration of the ABTS cation radical) and that of the antioxidant (by the method of the reduction of the iron ion, FRAP) were evaluated. Then the phenolic content of the aqueous extracts was determined and a correlation was studied between these two parameters.</p><p>The antioxidant tests showed that the plants counted have a good antioxidant power. The three most active extracts are those of the trunk and root bark of <em>Pseudocedrela kostchyi</em>, and the trunk bark of <em>Sterculia setigera</em>. The extract of the bark of the trunk of <em>Sterculia setigera </em>showed the highest total tannin and phenolic content, while that of the leaves of <em>Piliostigma reticulatum</em> showed the highest content of flavonoids. The analyses showed that there is a relationship between the total phenolic contents and the antioxidant capacities of all the extracts (R2 = 0.82).</p>The extracts of the trunk and root barks of <em>Pseudocedrela kostchyi</em>, and that of the trunk bark of <em>Sterculia setigera</em> showed the best antioxidant properties. They could be good candidates for the search for liver protective molecules.

scholarly journals Effects of Extraction Techniques on Total Phenolic Content and Antioxidant Capacities of Two Oregano Leaves

2014 ◽  
Vol 4 (1) ◽  
pp. 112 ◽  
Author(s):  
Ahmad Karimi ◽  
Byungjick Min ◽  
Cindi Brownmiller ◽  
Sun-Ok Lee
Keyword(s):  
Medicinal Plants ◽  
Antioxidant Capacity ◽  
Phenolic Content ◽  
Antioxidant Properties ◽  
Strong Relationship ◽  
Total Phenolic ◽  
Distilled Water ◽  
Extraction Techniques ◽  
Phenolic Contents ◽  
Solvent Type

<p>The effects of dried oregano leaves (Mediterranean and Mexican oregano) extracted using different extraction techniques, solvent types, and six different ratios of each solvent to distilled water on total phenolic (TP) content and antioxidant properties were examined. The Folin-Ciocalteu and 1,1-Diphenyl-2-picryl-hydrazyl (DPPH) assays were performed to assess the antioxidant capacity. The different species of oregano had a significant effect on TP content (107.6 vs. 34.5 mg GAEg<sup>-1</sup> in Mexican vs. Mediterranean oregano, respectively) (<em>P</em>&lt;0.05). Comparing extraction techniques, the vortex procedure significantly increased the measured TP content compared to sonication or shaking (<em>P</em>&lt;0.05); however, its effectiveness was sample species and solvent type dependent. Solvent type also had a significant impact on TP content of extracts in decreasing order of acetone, methanol, ethanol, and water (<em>P</em>&lt;0.05). The solvent:water ratio on TP content of each extract was significant (<em>P</em>&lt;0.05); higher TP content was measured for 40:60 and 60:40 acetone:water ratios for Mediterranean and 60:40 and 80:20 acetone:water ratios for Mexican oregano. The antioxidant capacity had a strong relationship with total phenolic contents. The current findings indicated that the species, extraction techniques, solvent type and the ratio of solvent:water had a significance influence on the TP content of two different species of dried oregano leaf, which may be a possible reason behind most variability reported on TP compounds of herbal and medicinal plants.</p>

scholarly journals Phenolic Content, Antioxidant Activity, 15-Lipoxygenase and Lipid Peroxidase Inhibitory Effects of two Medicinal Plants from Burkina Faso: Acacia macrostachya Reich. Ex Benth (Mimosaceae) and Lepidagathis anobrya NEES (Acanthaceae)

2020 ◽  
pp. 18-25
Author(s):  
Adjaratou C. Coulibaly ◽  
W. L. M. Esther B. Kabré ◽  
Mariam N. Traoré ◽  
Tata K. Traoré ◽  
Nouhoun Nignan ◽  
...  
Keyword(s):  
Medicinal Plants ◽  
Burkina Faso ◽  
Phenolic Content ◽  
Inflammatory Diseases ◽  
Folk Medicine ◽  
Reducing Power ◽  
Inhibitory Effect ◽  
Total Phenolic ◽  
Phenolic Contents ◽  
Lipoxygenase Inhibition

Acacia macrostachya (Mimosaceae) and Lepidagathis anobrya (Acanthaceae) are two medicinal plants used in Burkina Faso folk medicine for the treatment of inflammatory diseases. The purpose of this study was to assess the phenolic content, the antioxidant, lipoxygenase and lipid peroxidaseinhibitory effects of Acacia macrostachya and Lepidagathis anobrya.The experimental results revealed that Acacia mascrostachya and Lepidagathis anobrya have respective total phenolic contents  varies from 240.13 ± 0.44 and 30.88 ± 0.30 mg GAE / 100 mg extract; and total flavonoids contents of 2.30 ± 0.002 and 4.24 ± 0.28 QE / 100 mg of extract. The two plants demonstrated anti-free radicals (ABTS) capacities of 0.06 and 0.14 TEAC while the FRAP reducing power of 2.24 ± 0.08 and 4.43 ± 0.12 mmol AAE per 100 mg respectively. Acacia macrostachya and Lepidagathis anobrya showed significant inhibitory effect on lipid oxidation with the inhibition percentage values of 55.45 ± 1.48 and 66.36 ± 0.65 respectively. In the 15-lipoxygenase inhibition, Acacia macrostachya demonstrated very important inhibitory effect with the IC50 value of 1.32 ± 0.16 while the effect of Lepidagathis anobrya is very moderate.The results of this work demonstrated the interest of Acacia macrostachya and Lepidagathis anobrya in the management of inflammatory diseases.

SKRINING FITOKIMIA DAN UJI AKTIVITAS ANTIOKSIDAN DAN ANTITUMOR 20 TUMBUHAN OBAT ASAL KABUPATEN MANOKWARI

2008 ◽  
Vol 7 (1) ◽  
Author(s):  
Bimo Budi Santoso
Keyword(s):  
Antioxidant Activity ◽  
Medicinal Plants ◽  
Antitumor Activity ◽  
Traditional Method ◽  
Extraction Efficiency ◽  
Phenolic Content ◽  
Antioxidant Activities ◽  
Total Phenolic ◽  
Phenolic Contents ◽  
Total Phenolic Contents

<strong><em>Flavanoid, steroid, and terpenoid contents of 20 Manokwari medicinal plants were analyzed.  The antioxidant activity, total phenolic contents and antitumor activity of 20 Manokwari medicinal plants were also evaluated. The result shows that 83% positif to flavanoid test, 59% positif to terpenoid test and only 25% positif steroid. Antioxidant activity and total phenolic contents evaluated using Ferric Thiocianate (FTC) and Folin-Ciocalteu methods respectively. Antioxidant activity and total phenolic contents of medicinal plants were extracted by the traditional method, boiling in water and also in 80% methanol. Twenty plants evaluated in both exstracts have significantly varies of antioxidant activities and phenolic contents,  A significant and linier correlation coefficient between the antioxidant activity and the total phenolic content was found in both aqueous (R<sup>2</sup>= 0,77) and methanol (R<sup>2</sup> = 0,85). Antitumor activity was tested using cell maurine P-388 and only 2 of medicinal plants are active to inhibit cell maurine P-388. Comparing extraction efficiency of the two methods, the methanol extracted phenolic compounds more efficiently, and antioxidant activity of the extract was higher.</em></strong>

Evaluation of diuretic and antioxidant properties in aqueous bark and fruit extracts of pine

2020 ◽  
Vol 17 ◽  
Author(s):  
Hadi Shariati ◽  
Mohammad Hassanpour ◽  
Gholamreza Sharifzadeh ◽  
Asghar Zarban ◽  
Saeed Samarghandian ◽  
...  
Keyword(s):  
Antioxidant Activity ◽  
Phenolic Content ◽  
Antioxidant Properties ◽  
Pine Bark ◽  
Male Rats ◽  
Total Phenolic ◽  
Dependent Manner ◽  
Aqueous Extracts ◽  
Antioxidant Power ◽  
Dose Dependent

Objective: The present study has been carried out to evaluate the diuretic and antioxidant properties of pine herb in an animal model. Materials and Methods: 45 adult male rats were randomly divided into nine groups including: groups I (the negative control), groups II (positive control, furosemide 10 mg/kg), groups III to VIII (treatment groups received 100, 200, 400 mg/kg of the aqueous extracts of bark and fruit) and group IX received the combination of aqueous extract of bark (100 mg/kg) and the fruit (100 mg/kg). The urine output, glomerular filtration rate (GFR), electrolytes, urea, and creatinine levels were evaluated . Furthermore, the phenolic content and antioxidant activity of both extracts were also assessed using 2, 2-diphenyl-1-picrylhydrazyl (DPPH), ferric reducing antioxidant power (FRAP) and Folin–Ciocalteu methods. Results: The aqueous extracts of the pine bark and fruit increased the urinary output in a dose-dependent manner. The combination of the two extracts compared to the other extracts alone significantly increased the serum potassium level. This study also showed each extract increase creatinine clearance in a dose-dependent manner (p<0.01 and p<0.05). The increase of GFR in the combination group was not significant. The current data showed a significant increase in the total phenolic content in pine bark extract in compared with the fruit extract. Conclusion: The pine bark and fruit can be useful in the prevention and treatment of kidney stones due to the high antioxidant activity.

scholarly journals LC-ESI-QTOF/MS Characterization of Phenolic Compounds from Medicinal Plants (Hops and Juniper Berries) and Their Antioxidant Activity

Foods ◽  
2019 ◽  
Vol 9 (1) ◽  
pp. 7 ◽  
Author(s):  
Jiafei Tang ◽  
Frank R. Dunshea ◽  
Hafiz A. R. Suleria
Keyword(s):  
Antioxidant Activity ◽  
Phenolic Compounds ◽  
Medicinal Plants ◽  
Antioxidant Capacity ◽  
Phenolic Acids ◽  
Phenolic Content ◽  
Total Phenolic ◽  
High Concentration ◽  
Antioxidant Power ◽  
Pharmaceutical Industries

Hops (Humulus lupulus L.) and juniper berries (Juniperus communis L.) are two important medicinal plants widely used in the food, beverage, and pharmaceutical industries due to their strong antioxidant capacity, which is attributed to the presence of polyphenols. The present study is conducted to comprehensively characterize polyphenols from hops and juniper berries using liquid chromatography coupled with electrospray-ionization quadrupole time-of-flight mass spectrometry (LC-ESI-QTOF/MS) to assess their antioxidant capacity. For polyphenol estimation, total phenolic content, flavonoids and tannins were measured, while for antioxidant capacity, three different antioxidant assays including the 2,2-diphenyl-1-picrylhydrazyl (DPPH) antioxidant assay, the 2,2-azino-bis-3-ethylbenzothiazoline-6-sulfonic acid (ABTS) radical cation decolorization assay and the ferric reducing-antioxidant power (FRAP) assay were used. Hops presented the higher phenolic content (23.11 ± 0.03 mg/g dw) which corresponded to its strong antioxidant activity as compared to the juniper berries. Using LC-ESI-QTOF/MS, a total of 148 phenolic compounds were tentatively identified in juniper and hops, among which phenolic acids (including hydroxybenzoic acids, hydroxycinnamic acids and hydroxyphenylpropanoic acids) and flavonoids (mainly anthocyanins, flavones, flavonols, and isoflavonoids) were the main polyphenols, which may contribute to their antioxidant capacity. Furthermore, the HPLC quantitative analysis showed that both samples had a high concentration of phenolic acids and flavonoids. In the HPLC quantification, the predominant phenolic acids in hops and juniper berries were chlorogenic acid (16.48 ± 0.03 mg/g dw) and protocatechuic acid (11.46 ± 0.03 mg/g dw), respectively. The obtained results highlight the importance of hops and juniper berries as a rich source of functional ingredients in different food, beverage, and pharmaceutical industries.

Microencapsulation of Thunbergia laurifolia Crude Extract and Its Antioxidant Properties

2020 ◽  
Author(s):  
Catherine Nabbala ◽  
Wunwisa Krasaekoopt
Keyword(s):  
Antioxidant Activity ◽  
Crude Extract ◽  
Total Phenolic Content ◽  
Phenolic Content ◽  
Storage Temperature ◽  
Antioxidant Properties ◽  
Total Phenolic ◽  
Coating Materials ◽  
Antioxidant Power ◽  
Thunbergia Laurifolia

In this study, the antioxidant activity and total phenolic content of Thunbergia laurifolia Lindl. or Rang Chuet (RC) extracts from leaf, stem and rhizome were evaluated by using ferric reducing antioxidant power assay (FRAP) and the folin ciocalteu method for total phenolic compounds (TPC).The extracts were prepared by infusion using different amount of plant powder (2.5, 5.0, and 7.5 g) at different concentrations of ethanol as 0, 25, 50, and 75% and extraction time of 24, 48, and 72 h. The crude extract of 7.5 g leaf powder extracted for 72 h using water as the extraction solvent showed the highest antioxidant properties and total phenolic content. This extraction condition produced a FRAP content of 2.62 ± 0.01 mmol Fe2+/g that was significantly differed from those of the stem and rhizome and the highest TPC content of 877.36±18.75 (mg GAE/g). The crude extract from the leaf was subsequently encapsulated by using β-cylcodextrin (BCD) and maltodextrin 20DE (MD) as coating materials using freeze drying method. The encapsulated powder was investigated for its antioxidant activity. The highest encapsulation efficiency (EE) was obtained when only maltodextrin 20DE was used. The storage stability of encapsulated T. luarifolia leaf crude extract was then studied by storing the encapsulated powder at 35, 45, and 55°C for 5 weeks. The storage temperature had no effect on the stability of the encapsulated powder when TPC was used as the criteria unlike that of FRAP which was inconsistent during storage.

Ethnobotanical study, phytochemistry and antioxidant activity of medicinal plants used in the treatment of inflammation in two cities of Burkina Faso

2021 ◽  
Vol 2 (2) ◽  
pp. 01-012
Author(s):  
Armandine LEMA ◽  
Mindiédiba Jean BANGOU ◽  
Tangbadioa Hervé COULIDIATI ◽  
Mamadou SAWADOGO ◽  
Hyacinthe M THIOMBIANO ◽  
...  
Keyword(s):  
Antioxidant Activity ◽  
Medicinal Plants ◽  
Burkina Faso ◽  
Urban Areas ◽  
Polyphenolic Compounds ◽  
Total Phenolic ◽  
Ethnobotanical Study ◽  
Ethnobotanical Survey ◽  
Phytochemical Study ◽  
Traditional Practitioners

Background and Objective: The present study aimed to contribute to the knowledge of medicinal plants used in the treatment of inflammation in Burkina Faso, as well as to quanti fy the polyphenolic compounds content and to evaluate the antioxidant activity of two most solicited species. Materials and Methods: An ethnobotanical survey was carried out in the urban areas of Bobo-Dioulasso and Fada N'Gourma in order to collect sociodemographic and ethnobotanical data from traditional practitioners. Methanolic extracts of the plant organs were obtained using an extractor apparatus. The quantification of polyphenolic compounds contents was done by spectrophotometry, respectively with the Folin Ciocalteu reagent and aluminum trichloride. Likewise, antioxidant activity was evaluated by three methods (ABTS●+ DPPH● and FRAP) and the reading of optical densities was performed with the spectrophotometer. Results: One hundred and twelve (112) traditional practitioners were interviewed and seventy-three (73) plant species were identified in both areas. According to the frequency of quotation, Entada africana and Khaya senegalensis species were retained for further study. Phytochemical study revealed that the total phenolic content was high in the trunk bark of K. senegalensis (73.12 ± 1.8 mg GAE/100mg) and the total flavonoid content in the trunk bark of E. africana (8.42 ± 0.78 mg QE/100mg). Of the antioxidant activity, the highest value was observed at the level of the ABTS●+ radical inhibition method with the best result 13247.2 ± 219.84 µmol AAE/g (leaves of E. africana). Conclusion: The phytochemical analyses of these species indicate their richness in total phenolics and flavonoids contents, and could justify their use in the treatment of inflammatory diseases.

scholarly journals Study of Antioxidant, Anti-inflammatory, and DNA-Damage Protection Properties of Some Indian Medicinal Plants Reveal their Possible Role in Combating Psoriasis

2017 ◽  
Vol 5 (2) ◽  
pp. 141-149
Author(s):  
Neha Arora ◽  
Deepika Tripathi ◽  
Neha Pandey ◽  
Krishna Kumar Rai ◽  
Sanjay Kumar Rai ◽  
...  
Keyword(s):  
Dna Damage ◽  
Medicinal Plants ◽  
Antioxidant Properties ◽  
Drug Formulation ◽  
Trolox Equivalent Antioxidant Capacity ◽  
Total Phenolic ◽  
Ros Scavenging ◽  
Antioxidant Power ◽  
Anti Inflammatory ◽  
Indian Medicinal Plants

Reactive oxygen species (ROS) are generated due to severe oxidative stress, thereby resulting in pathogenesis of various disorders in humans, including psoriasis. DNA damage is the major manifestation of long term ROS exposure. ROS can be scavenged by natural antioxidant compounds present in medicinal plants. In this study, aqueous, methanolic and chloroform extracts of eleven dermatologically significant Indian medicinal plants were evaluated for their ROS scavenging and antioxidant properties, using 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging assay, Trolox equivalent antioxidant capacity (TEAC), Ferric reducing antioxidant power assay (FRAP), along with total phenolic content determination. Lipoxygenase inhibition assay was conducted to determine anti-inflammatory activities. DNA-damage protective capacities were also assessed using plasmid pBluescript II SK(–) DNA, where DNA damage was induced by Fenton reaction. The study reveals that the extracts of T. cordifolia, C. paniculatus, C. longa and A. vera performed far much better, in almost all the assays, with regards to P. corylifolia, a medicinal plant traditionally used to treat psoriasis, thus indicating these plants to be potent sources of effective drug formulation for treatment of psoriasis.Int. J. Appl. Sci. Biotechnol. Vol 5(2): 141-149

scholarly journals Far Infrared Irradiation Enhances Nutraceutical Compounds and Antioxidant Properties in Angelica gigas Nakai Powder

Antioxidants ◽  
2018 ◽  
Vol 7 (12) ◽  
pp. 189 ◽  
Author(s):  
Md Obyedul Kalam Azad ◽  
Jing Pei Piao ◽  
Cheol Ho Park ◽  
Dong Ha Cho
Keyword(s):  
Antioxidant Capacity ◽  
Phenolic Content ◽  
Antioxidant Properties ◽  
Far Infrared ◽  
Total Phenolic ◽  
Infrared Irradiation ◽  
Antioxidant Power ◽  
Angelica Gigas ◽  
Angelica Gigas Nakai ◽  
Nutraceutical Compounds

The aim of this study was to investigate the effect of far infrared irradiation (FIR) on nutraceutical compounds, viz. total phenolic content, total flavonoids, and antioxidant capacity, of Angelica gigas Nakai (AGN). The FIR treatment was applied for 30 min with varied temperatures of 120, 140, 160, 180, 200, 220, and 240 °C. Results showed that FIR increased total phenolic and flavonoid content in AGN at 220 °C. The HPLC results revealed higher quantities of decursin (62.48 mg/g) and decursinol angelate (41.51 mg/g) at 220 °C compared to control (38.70 mg/g, 27.54 mg/g, respectively). The antioxidant capacity of AGN was also increased at 220 °C, as measured by 1,1-diphenyl-2-picrylhydrazyl (DPPH), ferric reducing antioxidant power (FRAP), and the phosphomolybdenum (PPMD) method. A further increase of the FIR temperature caused a reduction of compound content. In addition, the results also showed a strong correlation between phenolic content and antioxidant properties of AGN powder. These findings will help to further improve the nutraceutical profile of AGN powder by optimizing the FIR conditions.

Quality characteristics of wheat flour dough and bread containing grape pomace flour

2017 ◽  
Vol 24 (3) ◽  
pp. 251-263 ◽  
Author(s):  
Monika Šporin ◽  
Martina Avbelj ◽  
Boris Kovač ◽  
Sonja Smole Možina
Keyword(s):  
Antioxidant Activity ◽  
Gallic Acid ◽  
Phenolic Content ◽  
Antioxidant Properties ◽  
Grape Pomace ◽  
Sensory Profile ◽  
Wheat Bread ◽  
Total Phenolic ◽  
Antioxidant Power ◽  
Ferric Reducing Antioxidant Power

Wheat bread was enriched with 6%, 10% and 15% dried and milled grape pomace flour from two grape cultivars: ‘Merlot’ and ‘Zelen’. Rheological, textural, sensory and antioxidant properties of the enriched dough and bread were evaluated, and compared to control samples. Grape cultivar had significant impact on the rheological characteristics of the dough, and on the sensory and antioxidant properties of the final bread. Development time and dough stability were longer when ‘Merlot’ grape pomace flour was added compared to ‘Zelen’ grape pomace flour and the control. Grape pomace flour addition affected bread volume, firmness, crumb and crust colour, and odour and taste intensity. Moreover, grape pomace flour addition resulted in a stickier and less springy crumb texture, and some negative sensorial properties, such as increased intensity of aftertaste and sand feeling in the mouth. The phenolic content and antioxidant activity of bread were positively correlated with grape pomace flour addition ( r = 0.987, p = 0.01 and r = 0.941, p = 0.01 between phenolic content and ferric reducing antioxidant power and phenolic content and 2,2-diphenyl-1-picrylhydrazyl, respectively). The highest total phenolic contents were 5.92 mg gallic acid equivalents (GAE)/g dw for ‘Merlot’ and 3.65 mg gallic acid equivalents /g dw for ‘Zelen’, which were seen for the bread prepared with the highest grape pomace flour addition (15%). The highest antioxidant activity determined by the 2,2-diphenyl-1-picrylhydrazyl and ferric reducing antioxidant power assays were seen for the bread prepared with the highest ‘Merlot’ grape pomace flour addition (15%). Dough characteristic and sensory profile are strongly influenced by cultivar of grape pomace flour. Based on results of sensory profiling, the variety ‘Zelen’ is suggested for use.

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