scholarly journals Evaluation of free radical scavenging activity of leaf of Hypericum mysorense Heyne

2017 ◽  
Vol 9 (4) ◽  
pp. 589
Author(s):  
Sornalakshmi V ◽  
Tresina PS ◽  
Paulpriya K ◽  
Veerabahu Ramasamy Mohan
Keyword(s):  
Free Radical ◽  
Radical Scavenging ◽  
Reducing Power ◽  
Ethanol Extract ◽  
Free Radical Scavenging ◽  
Model Systems ◽  
Radical Scavenger ◽  
Radical Scavenger Activity ◽  
Reducing Ability ◽  
Scavenger Activity

<em>Hypericum </em>is a well-known plant genus in herbal medicine. <em>Hypericum mysorense</em> is well known in folklore medicine for its varied therapeutic potential. The <em>in vitro </em>antioxidant activity of petroleum ether, benzene, ethyl acetate, methanol and ethanol extract of leaf of <em>Hypericum mysorense </em>have been tested using various antioxidant model systems viz; DPPH, hydroxyl, superoxide, ABTS and reducing power. The scavenging effect increases with the concentration of standard and samples. Among the solvent tested, ethanol extract exhibited highest DPPH (116.33% inhibition), hydroxyl (101.84%), superoxide (116.09%) and ABTS (119.22%) radical scavenger activity. Methanol extract of <em>H.mysorense </em>shows the highest reducing ability. The aim and purpose of this study is to show the significant free radical scavenging potential of <em>H.mysorense </em>leaf which can be experimented for the treatment of various free radical mediated ailments

Anti-inflammatory and Radical Scavenge Effects of Arctium lappa

1996 ◽  
Vol 24 (02) ◽  
pp. 127-137 ◽  
Author(s):  
Chun-Ching Lin ◽  
Jer-Min Lin ◽  
Jeng-Jer Yang ◽  
Shu-Chuan Chuang ◽  
Takashi Ujiie
Keyword(s):  
Free Radical ◽  
Radical Scavenging Activity ◽  
Radical Scavenging ◽  
Free Radical Scavenging ◽  
Radical Scavenger ◽  
Scavenging Activity ◽  
Paw Edema ◽  
Arctium Lappa ◽  
Radical Scavenger Activity ◽  
Scavenger Activity

The effects of Arctium lappa L. (root) on anti-inflammatory and free radical scavenger activity were investigated. Subcutaneous administration of A. lappa crude extract significantly decreased carrageenan-induced rat paw edema. When simultaneously treated with CCl4, it produced pronounced activities against CCl4-induced acute liver damage. The free radical scavenging activity of its crude extract was also examined by means of an electron spin resonance (ESR) spectrometer. The IC50 of A. lappa extract on superoxide and hydroxyl radical scavenger activity was 2.06 mg/m 11.8 mg/m1, respectively. These findings suggest that Arctium lappa possess free radical scavenging activity. The inhibitory effects on carrageenan-induced paw edema and CCl4-induced hepatotoxicity could be due to the scavenging effect of A. lappa.

scholarly journals Antioxidant-Free Radical Scavenging of Some Euphorbiaceae Herbs

2011 ◽  
Vol 2 (1) ◽  
pp. 146
Author(s):  
Titik Sunarni ◽  
Fransiska Leviana
Keyword(s):  
Acetic Acid ◽  
Free Radical ◽  
Radical Scavenging ◽  
Free Radical Scavenging ◽  
Free Radical Scavenger ◽  
Radical Scavenger ◽  
Radical Scavenger Activity ◽  
Ic50 Value ◽  
Scavenger Activity ◽  
Acetic Acid Water

In order to screen natural antioxidant, the research about antioxidant of some Euphobiaceae herbs, have been conducted. The air-dried herbs  of Euphorbia heterophylla L, Phyllanthus acidus (L.) Skeels, and Phyllanthus buxifolius Muell Arg were extracted with metanol. The obtained extract was concentrated and then suspended to produce n-hexane, ethyl acetat and aqueous fractions. Free radical scavenger activity against DPPH (1,1-diphenyl-2-pycrylhydrazyl) measured by spectrophotometric method  and the IC50 value was determined. The compounds of  active fraction had been identified by TLC method. All of the herbs showed activity as DPPH scavenger. Among these herbs, Euphorbia heterophylla L. and Phyllanthus buxifolius Muell, Arg. exhibited a strong free radical scavenging of ethyl acetat fraction with IC50 value 5,88 µg/ml and 4,64 µg/ml. The result of TLC by mobile phase n-buthanol-acetic acid-water (4:1:5) and acetic acid 15% showed flavonoid compound.Keywords: Euphorbiaceae herbs, antioxidant, DPPH, flavonoid

scholarly journals Comparative Nutrient Element and Antioxidant Characterization of Berry Fruit Species and Cultivars Grown in Hungary

HortScience ◽  
2008 ◽  
Vol 43 (6) ◽  
pp. 1711-1715 ◽  
Author(s):  
Attila Hegedűs ◽  
Emőke Balogh ◽  
Rita Engel ◽  
Béla Zoltan Sipos ◽  
János Papp ◽  
...  
Keyword(s):  
Antioxidant Capacity ◽  
Radical Scavenging ◽  
Elemental Content ◽  
Total Phenol Content ◽  
Radical Scavenger ◽  
Black Currant ◽  
Antioxidant Power ◽  
Radical Scavenger Activity ◽  
Reducing Ability ◽  
Scavenger Activity

Fruits of four berry species (strawberry, raspberry, red and black currants) were compared in their elemental composition (Al, B, Ba, Ca, Cu, Fe, K, Mg, Mn, Na, P, and Zn) and redox parameters involving total phenol content (TPC), ferric reducing ability (FRAP), 2,2′-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging, and total radical scavenger activity (TRSA). Berry cultivars contained significantly higher (P ≤ 0.05) amounts of most detected elements as compared with apple with many maximum elemental values demonstrated by the black currant ‘Otelo’. Black currant also had the greatest antioxidant capacity as demonstrated through all conducted assays. The results obtained through FRAP, TPC, and TRSA assays were closely correlated, whereas TRSA and DPPH varied independently. Our study provides valuable information on the antioxidant capacity of several berry species grown in Hungary and highlights the crucial influence of cultivar on elemental content and antioxidant power of berry fruits. This study demonstrated the ability to select berry cultivars for specific nutritional purposes or assign parental lines in functional breeding programs.

Determination of Free Radical Scavenging Potential in Cucumis melo (L). Fruit Extract

2021 ◽  
pp. 5084-5088
Author(s):  
Vidya R ◽  
Kalaivani K
Keyword(s):  
Free Radical ◽  
Cucumis Melo ◽  
Radical Scavenging Activity ◽  
Radical Scavenging ◽  
Reducing Power ◽  
Ethanolic Extract ◽  
Ethanol Extract ◽  
Free Radical Scavenging ◽  
Scavenging Activity ◽  
Fruit Extract

The human body has an elaborate antioxidant defence system. Antioxidants are manufactured within the body and may even be extracted from the food like fruits, vegetables, seeds, nuts, meats and oil. Fresh fruits and vegetables are a rich source of antioxidant vitamins such as A, C and E, that prevent cellular damage associated with many diseases. This present investigation was designed to evaluate the radical scavenging activity of ethanolic extract of Cucumis melo fruit. The in vitro free radical scavenging effect of the Cucumis melo (L) fruit extract was assessed by using 1,1 – diphenyl 2-picryl hydrazyl radical (DPPH), ABTS (2, 2’-Azinobis (3-ethyl Benz Thiazoline-6-Sulfonic acid) hydroxyl radical, reducing power and nitric oxide scavenging assay. The scavenging activity of the fruit extract was tested at different concentrations. C.melo fruit extract showed concentration dependant free radical scavenging activity. Ethanol extract of Cucumis melo fruit (EECMF) exhibited maximum scavenging activity against DPPH (64.46%), ABTS (70.52%) hydroxyl radical (62.57%), and nitric oxide (61.18%) in comparison with standard antioxidants. The reducing power of ethanol extract of C.melo fruit was found to be 0.11 at 0.2mg/ml and increased to 0.49 at 1mg/ml. These results clearly indicate that ethanolic extract of C.melo fruit has great potential of free radical scavenging activity and it may be used as a bioactive source of natural antioxidants for pharmacology of functional foods.

EVALUATION OF FREE RADICAL SCAVENGING POTENTIAL OF 7-HYDROXY–4-METHYLCOUMARIN ISOLATED FROM MIMOSA NILOTICA (L)

2021 ◽  
pp. 10-12
Author(s):  
S Srinivasan ◽  
A Rayar
Keyword(s):  
Free Radical ◽  
Radical Scavenging Activity ◽  
Radical Scavenging ◽  
Reducing Power ◽  
Ethanolic Extract ◽  
Ethanol Extract ◽  
Free Radical Scavenging ◽  
Free Radical Scavengers ◽  
Bioactive Constituents

Introduction:Medicinal plants have been used for the treatment of diseases all over the world before the advent of articial clinical drugs and are known to contain substances that can be used for therapeutic uses. Antioxidations act asreducing agents, free radical scavengers, quenchers of singlet oxygen molecule, and activators for antioxidative enzyme to reduce the damage caused by free radicals in biological pattern. Materials and Methods:The isolated organic compound from Mimosa nilotica was subjected to column chromatographic separation and was characterized 1 13 by UV, IR, H-NMR and C-NMR.DPPH assay was conducted to assess the effect of the ethanolic extract and 7-hydroxy–4-methylcoumarin. Result and Discussion:The reports of the in-vitro antioxidation assay indicated that the ethanol extract was more potent than 7-hydroxy–4- methylcoumarin. 7-hydroxy–4-methylcoumarin and ethanolic extractexpress excellent free radical scavenging activity. From the reports it is proved that the reducing power of bioactive constituent is associated with antioxidationpotential. Thus a correlation is proved between reducing power and the antioxidation effect. Conclusion:Previous reports are conrmed that the reducing power of bioactive constituents is associated with antioxidation potential. People who eat various parts of fruits and herbs have a lower risk of heart disease and some neurological diseases and there is evidence that some types of herbs, and fruits in general, protect against some malignant.

Sesquiterpene lactones fromLychnophora pohlii: neutrophil chemiluminescence inhibition and free radical scavenger activity

2006 ◽  
Vol 58 (6) ◽  
pp. 853-858 ◽  
Author(s):  
Alexandre Kanashiro ◽  
Luciana M. Kabeya ◽  
Cristiane F. F. Grael ◽  
Christiane O. Jordão ◽  
Ana Elisa C.S. Azzolini ◽  
...  
Keyword(s):  
Free Radical ◽  
Sesquiterpene Lactones ◽  
Free Radical Scavenger ◽  
Radical Scavenger ◽  
Radical Scavenger Activity ◽  
Scavenger Activity

scholarly journals Antiradical and Cytotoxic Activities of Varying Polarity Extracts of the Aerial Part ofEuphorbia hirtaL.

2013 ◽  
Vol 2013 ◽  
pp. 1-6 ◽  
Author(s):  
Shanmugapriya Perumal ◽  
Roziahanim Mahmud ◽  
Suthagar Pillai Piaru ◽  
Wei Cai Lee ◽  
Surash Ramanathan
Keyword(s):  
Linoleic Acid ◽  
Free Radical ◽  
Aerial Part ◽  
Radical Scavenging ◽  
Reducing Power ◽  
Free Radical Scavenging ◽  
Total Phenolic ◽  
Cytotoxic Activities ◽  
Uv Spectrophotometry ◽  
Etoh Extract

Euphorbia hirtais a well-known ethnomedicinal plant with diverse biological activities. The aim of the present study is to investigate the antiradical activities of various solvent extracts of the aerial part ofE. hirtaas well as to determine the possible cytotoxicity of these extracts. The aerial part ofE. hirtawas extracted with different solvent systems in order to increase polarity. The solvents used were hexane, dichloromethane (DCM), ethyl acetate (EA), ethanol (EtOH), and methanol (MeOH). The contents of total phenols and total flavonoids were analyzed by UV spectrophotometry, whereas the potential free radical-scavenging activities of the extracts were evaluated using the stable free radical 2,2-diphenyl-1-picrylhydrazyl (DPPH), theβ-carotene-linoleic acid bleaching system, and reducing power. The EtOH extract exhibited the highest total phenolic content (237.9±2.26 mg GAE/g), and DCM extract scored the highest total flavonoid content (121±0.15 mg CE/g). The MeOH extract showed a potent free radical-scavenging activity as evidenced by low EC50at 42.81 µg/mL. Interestingly, the EtOH extract demonstrated the highest reducing power activity with EC50value of 6.18 µg/mL. Inβ-carotene-linoleic acid assay, oxidation of linoleic acid was effectively inhibited by DCM extract with96.15±0.78%. All the extracts showed no cytotoxic activity against Vero cells.

scholarly journals EVALUATION OF ANTIOXIDANT AND FREE RADICAL SCAVENGING ACTIVITIES OF DIFFERENT SOLVENT EXTRACTS OF LEAVES OF PIPER UMBELLATUM

2017 ◽  
Vol 10 (2) ◽  
pp. 274
Author(s):  
Sethupandian Geetha ◽  
Kokkaiah Irulandi ◽  
Palanichamy Mehalingam
Keyword(s):  
Antioxidant Activity ◽  
Free Radical ◽  
Ethyl Acetate ◽  
Methanol Extract ◽  
Radical Scavenging Activity ◽  
Radical Scavenging ◽  
Reducing Power ◽  
Free Radical Scavenging ◽  
Frap Assay ◽  
Radical Scavenging Properties

Objective: This study was designed to determine the Total phenol, flavonoid content, antioxidant and free radical scavenging properties of different solvent extracts of Piper umbellatum.  Methods: Different solvent extracts evaluated with DPPH radical scavenging activity and Reducing power activity.Results: The presence of phenol and flavonoid showed highly in the methanol extracts than ethyl acetate and acetone extracts. All the extracts have various level of antioxidant activity. Methanol solvent extract have good extraction and show significant antioxidant activity. The effect of reducing power of methanol extract revealed good antioxidant activity compare with other tested extracts.Conclusion: On the basis of the above results we concluded that methanol extract of Piper umbellatum whole plant extracts shows significant antioxidant activity than ethyl acetate and acetone extracts.Keywords: Piper umbellatum, Antioxidant, DPPH, FRAP assay, Polar, Non polar solvents

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