scholarly journals Baruch Blumberg (1925-2011) and the discovery of the Hepatitis B virus

2021 ◽  
pp. 18-21
Author(s):  
Bob Weintraub
Keyword(s):  
Hepatitis B Virus ◽  
Liver Cancer ◽  
Hepatitis B ◽  
Genetic Polymorphisms ◽  
Nobel Prize ◽  
Primary Liver Cancer ◽  
Diagnostic Methods ◽  
Inherited Susceptibility ◽  
B Virus

Baruch Blumberg’s research was designed to gain a better understanding of the role of human genetic polymorphisms in relation to inherited susceptibility to disease. This led to the discovery of the hepatitis B virus, diagnostic methods for viral detection, and a vaccine. The vaccination program has prevented the death of millions from primary liver cancer. It was the first widely used vaccine against cancer. For his work with the hepatitis B virus, Blumberg was honored in 1976 by the award of the Nobel Prize in Medicine or Physiology.

Hepatitis B vaccine

1985 ◽  
Vol 23 (13) ◽  
pp. 49-51
Keyword(s):  
Chronic Hepatitis ◽  
Hepatitis B Virus ◽  
Liver Cancer ◽  
Hepatitis B ◽  
Acute Hepatitis ◽  
World Wide ◽  
Primary Liver Cancer ◽  
Hepatitis B Vaccine ◽  
Common Cause ◽  
B Virus

The hepatitis B virus is the most common cause world-wide of acute hepatitis, and also causes chronic hepatitis, cirrhosis1 and primary liver cancer.2 It can now be prevented by a vaccine. How should this best be used?

scholarly journals Clinical characteristics of patients with hepatitis B virus related liver cirrhosis and primary liver cancer

2015 ◽  
Vol 23 (17) ◽  
pp. 2798
Author(s):  
Feng Lv ◽  
Yu-Feng Gao ◽  
Jian-Guo Rao ◽  
Wei Zhang ◽  
Gui-Zhou Zou ◽  
...  
Keyword(s):  
Liver Cirrhosis ◽  
Hepatitis B Virus ◽  
Liver Cancer ◽  
Hepatitis B ◽  
Clinical Characteristics ◽  
Primary Liver Cancer ◽  
B Virus

scholarly journals Hepatitis B virus and primary liver cancer

1978 ◽  
Vol 74 (1) ◽  
pp. 163 ◽  
Author(s):  
Thomas V. Nowak ◽  
Brian W. Kennedy ◽  
Lawrence S. Hurwitz ◽  
Rajiv R. Varma
Keyword(s):  
Hepatitis B Virus ◽  
Liver Cancer ◽  
Hepatitis B ◽  
Primary Liver Cancer ◽  
B Virus

scholarly journals The role of infection by opisthorchis viverrini, hepatitis B virus, and aflatoxin exposure in the etiology of liver cancer in thailand. A correlation study

Cancer ◽  
1991 ◽  
Vol 68 (11) ◽  
pp. 2411-2417 ◽  
Author(s):  
Petcharin Srivatanakul ◽  
D. Maxwell Parkin ◽  
Yuan-Zhou Jiang ◽  
Myriam Khlat ◽  
U-Thai Kao-Ian ◽  
...  
Keyword(s):  
Hepatitis B Virus ◽  
Liver Cancer ◽  
Hepatitis B ◽  
Correlation Study ◽  
Opisthorchis Viverrini ◽  
B Virus

scholarly journals THE RISK OF HEPATOCELLULAR CARCINOMA ON PATIENTS DIAGNOSED WITH HEPATITIS B AND HEPATITIS D (2012-2015)

2016 ◽  
Vol 63 (2) ◽  
pp. 153-158
Author(s):  
Irina Dinu ◽  
◽  
Mihai Voiculescu ◽  
Andreea Radasan ◽  
◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Hepatitis B Virus ◽  
Liver Cancer ◽  
Hepatitis B ◽  
Urban Areas ◽  
Primary Liver Cancer ◽  
Close Monitoring ◽  
Hepatitis D ◽  
Mortality And Morbidity ◽  
B Virus

Introduction. Hepatocellular carcinoma is the most common primary liver cancer (90%), the 5th neoplasia in terms of incidence and the 3rd mortality cause worldwide (1). This increased mortality is the consequence of diagnosis in an advanced state and of the fact that most HCC develop based on a chronic hepatic pathology. In Romania, around 7% of the population is affected by chronic hepatitis B, the incidence of this disease being increased in urban areas (2). The sooner the hepatitis B virus infection occurs in life, the higher the probability is, for this to become chronic and to lead to cirrhosis or liver cancer. Hepatitis D only occurs among people who are infected with the Hepatitis B virus because HDV is an incomplete virus that requires the helper function of HBV to replicate. Objective of the study. The main purpose of the surveillance and/or screening is to decrease mortality and morbidity by means of liver cancer for patients diagnosed with hepatitis B and hepatitis D. Matherial and methods. The study was conducted on a number of 102 patients diagnosed with viral hepatitis (HBV, HDV+HBV) admitted at the “Fundeni” Hospital, Bucharest, between 2012-2015. Two batches of patients were taken into account (patients with hepatitis B and hepatitis D). The viral load and chosen treatment were clinically, biochemically and imagistically evaluated. Results. We have noticed a significant increase in patients diagnosed with hepatitis B and D. The existence of the hepatitis D infection in patients diagnosed with hepatitis B significantly increases the occurence potential of liver cancer. The hepatic destruction degree by means of cirrhotic liver occurence respectively hepatic cirrhosisis much higher for patients diagnosed with hepatitis D. Conclusions. The close monitoring of the patients in this research program brings real benefit for the prevention of liver cancer and diagnosing it early, having a much better prognosis on the quality of life.

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