scholarly journals A IMPORTÂNCIA DA PROTEÇÃO TÓPICA E MECÂNICA PARA PREVENÇÃO DO CÂNCER DE PELE

2021 ◽  
Author(s):  
Esther Carneiro Costa ◽  
Leticia Santiago Capistrano ◽  
Sarah Teixeira Almeida ◽  
Giovanna Matias Duarte
Keyword(s):  
Skin Neoplasms ◽  
Sunscreening Agents

Introdução: O câncer de pele é a neoplasia mais frequente no Brasil. Sua incidência está relacionada, mormente, à exposição aos raios ultravioletas (UV), fator associado à ausência de prevenção. Destarte, é evidente a necessidade dos cuidados com a pele, mediante uso de protetor solar, de acordo com o local do corpo a ser protegido e o tipo de pele. Simultaneamente, urge a diminuição da exposição aos raios solares. Objetivo: Realizar uma revisão de literatura reconhecendo a importância da proteção solar como método efetivo na prevenção do câncer de pele. Materiais e métodos: Foi realizada uma revisão de literatura a partir da análise de 13 publicações científicas publicadas entre 2013 e 2020. Destes, foram selecionados sete, na base de dados PubMed e Scielo, utilizando como termos de pesquisa: “Skin Neoplasms”, “Sunscreening Agents” e “Oncology”, terminologias de acordo com o sistema de Descritores em Ciências da Saúde (DeCs). Resultados: Estudos constataram a possibilidade de 90% dos cânceres de pele não melanomas e 65% dos melanomas estarem associados à exposição solar inadequada. Isso se deve, comumente, à falta de informação da população acerca da prevenção, fato evidenciado pela postura dos principais grupos de risco do câncer de pele (trabalhadores expostos ao ar livre). De acordo com pesquisas, muitos desses declararam que nunca ou raramente usavam camisa de manga comprida e chapéu. Portanto, são necessárias maiores explanações a respeito da necessidade da aplicação diária de proteção solar e do uso de roupas fotoprotetoras, além de evitar exposição solar direta, principalmente das 10 às 16 horas. Conclusão: Destarte, conclui-se que são necessárias mais medidas fotoeducativas, a exemplo da disseminação de informações acerca da necessidade do uso regular de protetor solar, com, no mínimo, fator de proteção solar (FPS) 30, além de estratégias de fotoproteção mecânica, com o intuito de prevenir o câncer cutâneo.

Pigment Cell Skin Neoplasms in Children and Adolescents: Searching Skin Melanoma Diagnostic Markers

2016 ◽  
Vol 3 (1) ◽  
pp. 16-23
Author(s):  
G.M. Volgareva ◽  
◽  
A.V. Lebedeva ◽  
V.G. Polyakov ◽  
◽  
...  
Keyword(s):  
Children And Adolescents ◽  
Pigment Cell ◽  
Skin Neoplasms ◽  
Diagnostic Markers ◽  
Skin Melanoma

The frequency of different epithelial tumors of the skin in those working with industrial carcinogens

2020 ◽  
pp. 616-616
Author(s):  
A. V. Derevnina ◽  
N. I. Izmerova ◽  
I. Y. Chistova
Keyword(s):  
Working Conditions ◽  
Skin Neoplasms ◽  
Diagnostic Methods ◽  
Epithelial Tumors ◽  
Production Factors

To identify tumors and assess the risks of malignancy of different epithelial skin neoplasms working with industrial carcinogens, not only the influence of production factors was considered, but also visual diagnostic methods (dermatoscopy) were used, according to the assessment of working conditions.

scholarly journals Sox9 expression in canine epithelial skin tumors

2015 ◽  
Vol 59 (3) ◽  
Author(s):  
E. Fantinato ◽  
L. Milani ◽  
G. Sironi
Keyword(s):  
Stem Cells ◽  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Hair Follicle ◽  
Squamous Cell ◽  
Expression Patterns ◽  
Regulatory Gene ◽  
Skin Neoplasms ◽  
Stem Cell Marker ◽  
Molecular Characteristics

<p><em>Sox9</em> is a master regulatory gene involved in developmental processes, stem cells maintenance and tumorigenesis. This gene is expressed in healthy skin but even in several skin neoplasms, where its expression patterns often resembles those of the developing hair follicle. In this study, samples from eleven different types of canine skin neoplasms (squamous papilloma, squamous cell carcinoma, infundibular keratinizing acanthoma, inferior tricholemmoma, isthmic tricholemmoma, trichoblastoma, trichoepitelioma, malignant trichoepitelioma, pilomatricoma, subungual keratoacanthoma, subungual squamous cell carcinoma) were immunohistochemically stained and evaluated for <em>Sox9</em> with the aim to correlate tumor phenotype with molecular characteristics that may help to better define tumor development, contribute to its diagnosis and clinical management. Keratoacanthoma excluded, all the skin neoplasms examined showed a variable positivity to <em>Sox9</em>, especially in the basal layers, but with major intensity in neoplasms developing from the bulge region of the hair follicle, as trichoblastoma. According to our results, <em>Sox9</em> could be employed as a stem cell marker to better assess the role of stem cells in canine epidermal and follicular tumors.</p>

scholarly journals Epidemiology of basal cell carcinomas and squamous cell carcinomas in a Department of Dermatology: a 5 year review

2012 ◽  
Vol 87 (2) ◽  
pp. 212-219 ◽  
Author(s):  
Pedro Andrade ◽  
Maria Manuel Brites ◽  
Ricardo Vieira ◽  
Angelina Mariano ◽  
José Pedro Reis ◽  
...  
Keyword(s):  
Skin Cancer ◽  
Squamous Cell ◽  
Basal Cell ◽  
Skin Neoplasms ◽  
Squamous Cell Carcinomas ◽  
Exposed Skin ◽  
Non Melanoma Skin Cancer ◽  
Basal Cell Carcinomas ◽  
Malignant Skin ◽  
Melanoma Skin

BACKGROUND: Non-melanoma skin cancer, a common designation for both basal cell carcinomas and squamous cell carcinomas, is the most frequent malignant skin neoplasm. OBJECTIVE: Epidemiologic characterization of the population with Non-melanoma skin cancer. METHODS: Retrospective analysis of all patients diagnosed with Non-melanoma skin cancer based on histopathologic analysis of all incisional or excisional skin biopsies performed between 2004 and 2008 in a Department of Dermatology. RESULTS: A total of 3075 Non-melanoma skin cancers were identified, representing 88% of all malignant skin neoplasms (n=3493) diagnosed in the same period. Of those, 68,3% were basal cell carcinomas. Most Non-melanoma skin cancer patients were female and over 60 years old. Of all Non-melanoma skin cancer, 81,7% (n=1443) were located in sun-exposed skin, and represented 95,1% of malignant skin neoplasms in sun-exposed skin. Non-melanoma skin cancer was the most frequent malignant skin neoplasm in most topographic locations, except for abdomen and pelvis - over 95% of all malignant skin neoplasms in the face, neck and scalp were Non-melanoma skin cancer. Basal cell carcinomas were clearly predominant in all locations, except in upper and lower limbs, lower lip and genitals, where squamous cell carcinomas represented respectively 77,7%, 77,4%, 94,7% and 95,3% of the Non-melanoma skin cancers. CONCLUSION: Being the most common skin cancer, Non-melanoma skin cancer should be under constant surveillance, in order to monitor its epidemiologic dynamics, the efficiency of preventive measures and the adaptation of the healthcare resources.

scholarly journals Clinical characteristics of mastocytoma in dogs

2020 ◽  
Vol 22 (98) ◽  
pp. 144-153
Author(s):  
B. B. Ivashkiv ◽  
A. R. Mysak ◽  
V. V. Pritsak
Keyword(s):  
Subcutaneous Tissue ◽  
Skin Neoplasms ◽  
Incidence Rates ◽  
Skin Tumors ◽  
Practical Significance ◽  
Biological Behavior ◽  
German Shepherd ◽  
Biopsy Material ◽  
Central Type ◽  
Diffuse Infiltration

According to foreign researchers, mastocytoma is one of the most common (7-12 %) skin tumors in dogs. This neoplasia is caused by excessive proliferation of mast cells and characterized by a specific clinical course, unpredictable biological behavior and prognosis. Researches of clinical and morphological features of mastocytoma in geographical populations of Ukraine has not only scientific and general biological interest, but also important practical significance. The purpose of the research was to establish the frequency of spreading, the features of the clinical ostent and pathogenesis of cutaneous mastocytoma in dogs in conditions in Lviv and in the suburban zone of the regional center. The research was performed on dogs with skin tumors (n = 128), including 24 of them with mastocytoma, who came to the Department of Surgery and Clinic of Small Pets of Stepan Gzhytskyj LNUVMB during 2016–2020. The diagnosis on mastocytoma was verified by the results of physical examination and cytological examination of biopsy material of neoplasms. It was found that in the structure of oncological diseases of dogs the share of skin neoplasms was 32.16 %. Among animals with skin neoplasms, mastocytoma was diagnosed in 18.75 % of dogs aged 4 to 16 years. The highest incidence rates were found among animals aged 8 to 11 years; the median incidence was 9.5 years and fashion – 9 years. In terms of breeds, cutaneous mastocytoma was found in dogs of the breed: Rottweiler – 16.7 %, Sharpei – 12.5 %, Staffordshire Terrier – 12.5 %, Labrador – 8.3 %, Boxer – 8.3 %, Doberman – 8.3 %, chow-chow – 8.3 %. At the same time, the German Shepherd, Alabai, Spaniel, French Bulldog and Pug cases of the disease were isolated (4.2 %). Among sick animals, dogs accounted for 54.2 % and females for 45.8 %. It was found that in 41.7 % of the studied animals the rate of neoplasia was extremely rapid, because in 56.5 ± 1.91 days the tumors were doubled in size, which is evidence of significant aggressiveness of tumor growth. In 29.2 % of dogs the time of doubling the size of the primary tumor reached 122.1 ± 10.6 days, in 20.8 % of dogs the period of tumor development lasted for two years. In 8.3 % of dogs, the dynamics of neoplasia development is not clear. Sonography has shown that skin mastocytomas are usually visualized as heterogeneous, with uneven edges and fuzzy contours hypoechoic structures. Visualization of solid hypervascular foci with central type of vascularization, on the background of diffuse infiltration of neoplasia in the deeper layers of the skin and subcutaneous tissue, with a pronounced perinodular inflammatory reaction of the surrounding tissues is a sign of malignancy of the mastocytoma. The generalization of the neoplastic process in the internal organs was found, in particular the spleen, may indicate a predominance of the hematogenous route of metastasis of the mastocytoma. The obtained data complement and expand knowledge about the pathogenesis of mastocytoma in dogs, and also highlight the frequency of spreading and course features of this oncological pathology in a separate geographical population of Ukraine.

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