scholarly journals Role of cerebrospinal fluid in differentiation of human dental pulp stem cells into neuron-like cells

2020 ◽  
Vol 53 (3) ◽  
pp. 292-300
Author(s):  
Ghazaleh Goudarzi ◽  
Hatef Ghasemi Hamidabadi ◽  
Maryam Nazm Bojnordi ◽  
Azim Hedayatpour ◽  
Ali Niapour ◽  
...  
Keyword(s):  
Stem Cells ◽  
Cerebrospinal Fluid ◽  
Dental Pulp ◽  
Dental Pulp Stem Cells ◽  
Human Dental Pulp

scholarly journals The role of osteomodulin on osteo/odontogenic differentiation in human dental pulp stem cells

2019 ◽  
Vol 19 (1) ◽  
Author(s):  
Wenzhen Lin ◽  
Li Gao ◽  
Wenxin Jiang ◽  
Chenguang Niu ◽  
Keyong Yuan ◽  
...  
Keyword(s):  
Stem Cells ◽  
Dental Pulp ◽  
Dental Pulp Stem Cells ◽  
Odontogenic Differentiation ◽  
Human Dental Pulp

scholarly journals Role of p16INK4a and BMI-1 in oxidative stress-induced premature senescence in human dental pulp stem cells

Redox Biology ◽  
2017 ◽  
Vol 12 ◽  
pp. 690-698 ◽  
Author(s):  
Cristina Mas-Bargues ◽  
José Viña-Almunia ◽  
Marta Inglés ◽  
Jorge Sanz-Ros ◽  
Juan Gambini ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Stem Cells ◽  
Dental Pulp ◽  
Dental Pulp Stem Cells ◽  
Premature Senescence ◽  
Human Dental Pulp ◽  
Stress Induced Premature Senescence

scholarly journals Pentraxin-3 Modulates Osteogenic/Odontogenic Differentiation and Migration of Human Dental Pulp Stem Cells

2019 ◽  
Vol 20 (22) ◽  
pp. 5778
Author(s):  
Yeon Kim ◽  
Joo-Yeon Park ◽  
Hyun-Joo Park ◽  
Mi-Kyoung Kim ◽  
Yong-Il Kim ◽  
...  
Keyword(s):  
Stem Cells ◽  
Dental Pulp ◽  
Tissue Repair ◽  
Therapeutic Potential ◽  
Dental Pulp Stem Cells ◽  
Pentraxin 3 ◽  
Odontogenic Differentiation ◽  
Human Dental Pulp ◽  
And Migration

Pentraxin-3 (PTX3) is recognized as a modulator of inflammation and a mediator of tissue repair. In this study, we characterized the role of PTX3 on some biological functions of human dental pulp stem cells (HDPSCs). The expression level of PTX3 significantly increased during osteogenic/odontogenic differentiation of HDPSCs, whereas the knockdown of PTX3 decreased this differentiation. Silencing of PTX3 in HDPSCs inhibited their migration and C-X-C chemokine receptor type 4 (CXCR4) expression. Our present study indicates that PTX3 is involved in osteogenic/odontogenic differentiation and migration of HDPSCs, and may contribute to the therapeutic potential of HDPSCs for regeneration and repair.

scholarly journals The role of lysyl oxidase-like 2 in the odontogenic differentiation of human dental pulp stem cells

2013 ◽  
Vol 35 (6) ◽  
pp. 543-549 ◽  
Author(s):  
Joo-Hyun Kim ◽  
Eun-Hyang Lee ◽  
Hye-jeong Park ◽  
Eui-Kyun Park ◽  
Tae-Geon Kwon ◽  
...  
Keyword(s):  
Stem Cells ◽  
Dental Pulp ◽  
Lysyl Oxidase ◽  
Dental Pulp Stem Cells ◽  
Odontogenic Differentiation ◽  
Human Dental Pulp

scholarly journals The Role of ORAI1 in the Odontogenic Differentiation of Human Dental Pulp Stem Cells

2015 ◽  
Vol 94 (11) ◽  
pp. 1560-1567 ◽  
Author(s):  
S. Sohn ◽  
Y. Park ◽  
S. Srikanth ◽  
A. Arai ◽  
M. Song ◽  
...  
Keyword(s):  
Stem Cells ◽  
Dental Pulp ◽  
Dental Pulp Stem Cells ◽  
Odontogenic Differentiation ◽  
Human Dental Pulp

scholarly journals Erratum to: The role of lysyl oxidase-like 2 in the odontogenic differentiation of human dental pulp stem cells

2013 ◽  
Vol 36 (5) ◽  
pp. 476-476
Author(s):  
Joo-Hyun Kim ◽  
Eun-Hyang Lee ◽  
Hye-jeong Park ◽  
Eui-Kyun Park ◽  
Tae-Geon Kwon ◽  
...  
Keyword(s):  
Stem Cells ◽  
Dental Pulp ◽  
Lysyl Oxidase ◽  
Dental Pulp Stem Cells ◽  
Odontogenic Differentiation ◽  
Human Dental Pulp

The role of asporin in mineralization of human dental pulp stem cells

2011 ◽  
Vol 226 (6) ◽  
pp. 1676-1682 ◽  
Author(s):  
Eun-Hyang Lee ◽  
Hye-Jeong Park ◽  
Ji-Hyun Jeong ◽  
Young-Jin Kim ◽  
Du-Won Cha ◽  
...  
Keyword(s):  
Stem Cells ◽  
Dental Pulp ◽  
Dental Pulp Stem Cells ◽  
Human Dental Pulp

scholarly journals Condition medium of cerebrospinal fluid and retinoic acid induces the transdifferentiation of human dental pulp stem cells into neuroglia and neural like cells

2017 ◽  
Vol 50 (2) ◽  
pp. 107 ◽  
Author(s):  
Sara Haratizadeh ◽  
Maryam Nazm Bojnordi ◽  
Shahram Darabi ◽  
Narges Karimi ◽  
Mehrdad Naghikhani ◽  
...  
Keyword(s):  
Stem Cells ◽  
Cerebrospinal Fluid ◽  
Retinoic Acid ◽  
Dental Pulp ◽  
Dental Pulp Stem Cells ◽  
Human Dental Pulp

scholarly journals Angelica sinensis polysaccharide promotes the proliferation and osteogenic differentiation of human dental pulp stem cells (hDPSCs) by activating the wnt/β-catenin pathway

2021 ◽  
Vol 13 (4) ◽  
pp. 31-37
Author(s):  
Tiantian Mao ◽  
Youjian Peng ◽  
Ruobing Peng ◽  
Xiaoying Wei
Keyword(s):  
Stem Cells ◽  
Osteogenic Differentiation ◽  
Immune Regulation ◽  
Dental Pulp ◽  
Periodontal Diseases ◽  
Dental Pulp Stem Cells ◽  
Angelica Sinensis ◽  
Biological Functions ◽  
Human Dental Pulp

Human dental pulp stem cells (hDPSCs) are capable of forming mineralized nodules. The proliferation and osteogenic differentiation of hDPSCs are very important for alleviating tooth defects caused by related diseases. Angel-ica polysaccharide (ASP) is the main bioactive ingredient extracted from the angelica root. ASP has a variety of biological functions, including immune regulation, antitumor activity, and hematopoiesis. However, its possible effects on hDPSCs are still unclear. In this study, we aimed to investigate the role of ASP in periodontal diseases. We found that ASP promoted the proliferation of hDPSCs and osteogenic differentiation of hDPSCs. We further found that it promoted the expression of osteogenic-related genes, including ALP, RUNX2, Col1a1, and OCN. Mechanically, we found that ASP activated the Wnt/β-catenin pathway. In conclusion, our results suggested that ASP promoted the proliferation and osteogenic differentiation of hDPSCs via the Wnt/β-catenin pathway.

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