scholarly journals An evaluation study of the determinants of future perspective and global Quality of Life in Spanish long-term premenopausal early-stage breast cancer survivors

2016 ◽  
Vol 2 ◽  
pp. 165-170 ◽  
Author(s):  
Juan Ignacio Arraras ◽  
Jose Juan Illarramendi ◽  
Esteban Salgado ◽  
Susana de la Cruz ◽  
Gemma Asin ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Quality Of Life ◽  
Breast Cancer Survivors ◽  
Early Stage ◽  
Evaluation Study ◽  
Future Perspective ◽  
Global Quality ◽  
Global Quality Of Life

Effect of patient education on quality-of-life, pain and fatigue in breast cancer survivors: A systematic review and meta-analysis

2021 ◽  
pp. 026921552110310
Author(s):  
Patricia Martínez-Miranda ◽  
Maria Jesús Casuso-Holgado ◽  
José Jesús Jiménez-Rejano
Keyword(s):  
Breast Cancer ◽  
Quality Of Life ◽  
Patient Education ◽  
Cancer Survivors ◽  
Breast Cancer Survivors ◽  
Short Term ◽  
Emotional Quality ◽  
Global Quality ◽  
Global Quality Of Life

Objective: To synthesise the existing evidence about the effect of patient education, either used alone or as adjunctive therapy, on the improvement of quality of life, pain and fatigue in adult breast cancer survivors. Data sources: We searched PubMed, Web of Science, CINAHL, SCOPUS, Cochrane Plus, PEDro, Dialnet and Clinicaltrials.gov databases. Methods: We conducted this systematic review in accordance with the PRISMA statement. Only randomised controlled trials with adult breast cancer survivors were included. We assessed the methodological quality of the studies using the PEDro scale and the Cochrane risk-of-bias tool. We synthesised evidence using the GRADE tool. Results: We included 14 studies (PEDro 4–8 points) comprising 1749 adult women who survived breast cancer, of which we included 12 in the quantitative analysis. There were statistically significant short-term benefits for improved global quality-of-life (standardised mean difference [SMD] = 0.43, P = 0.05, 95% CI [0.00, 0.85]; GRADE: low certainty; not important), emotional quality-of-life (SMD = 0.32, P = 0.04, 95% CI [0.02, 0.62]) and fatigue (SMD = 0.24, P = 0.0004, 95% CI [0.11, 0.37]; GRADE: low certainty; not important). However, there were not statistically significant for pain severity (SMD = −0.05, P = 0.67, 95% CI [−0.26, 0.17]; GRADE: low certainty; not important) and fear to recurrence (SMD = −0.05, P = 0.68, 95% CI [−0.31, 0.20]; GRADE: moderate certainty; not important). Conclusion: Patient education have a significative effect in short-term global quality-of-life, emotional quality-of-life and fatigue, though all the results were classified as ‘not important’.

scholarly journals Mobile App for Symptom Management and Associated Quality of Life During Systemic Treatment in Early Stage Breast Cancer: Nonrandomized Controlled Prospective Cohort Study

10.2196/17408 ◽  
2020 ◽  
Vol 8 (8) ◽  
pp. e17408
Author(s):  
Cvetka Grašič Kuhar ◽  
Tjaša Gortnar Cepeda ◽  
Timotej Kovač ◽  
Matjaž Kukar ◽  
Nina Ružić Gorenjec
Keyword(s):  
Breast Cancer ◽  
Quality Of Life ◽  
Systemic Therapy ◽  
Early Stage ◽  
Intervention Group ◽  
Health Resources ◽  
Control Group ◽  
Global Quality ◽  
Global Quality Of Life

Background Providing patients with cancer who are undergoing systemic therapy with useful information about symptom management is essential to prevent unnecessary deterioration of quality of life. Objective The aim was to evaluate whether use of an app for symptom management was associated with any change in patient quality of life or use of health resources. Methods Outpatients with early stage breast cancer receiving systemic therapy were recruited at the Institute of Oncology in Ljubljana, Slovenia. Patients who received systemic therapy between December 2017 and March 2018 (control group) and between April 2018 and September 2018 (intervention group) were eligible. All patients received standard care, but only those in the intervention group were asked to use mPRO Mamma, an Android-based smartphone app, in addition. The app supported daily tracking of 50 symptoms, allowed users to grade their symptom severity (as mild, moderate, or severe), and also provided in-depth descriptions and recommendations based on reported symptom level. Patient-reported outcomes in both groups were assessed through the European Organisation for Research and Treatment of Cancer (EORTC) core (C-30) and breast cancer (BR-23) questionnaires, as well as a questionnaire about health resources use. The primary outcomes were the difference in the global quality of life between groups and the difference in summary score of the EORTC C-30 questionnaire between groups after 3 time periods (the first week of treatment, the first treatment cycle, and the entire treatment). The secondary outcome was the use of health resources (doctor visits and hospitalizations) in each time period. Other scales were used for exploratory analysis. Results The mean difference between the intervention group (n=46) and the control group (n=45) in global quality of life (adjusted for baseline and type of surgery) after the first week was 10.1 (95% CI 1.8 to 18.5, P=.02). The intervention group summary scores were significantly higher than those of the control group after the first week (adjusted mean difference: 8.9, 95% CI 3.1 to 14.7, P=.003) and at the end of treatment (adjusted mean difference: 10.6, 95% CI 3.9 to 17.3, P=.002). Use of health resources was not statistically significant between the groups in either the first week (P=.12) or the first treatment cycle (P=.13). Exploratory analysis findings demonstrated clinically important improvements (indicated by EORTC C-30 or BR-23 scale scores)—social, physical, role, and cognitive function were improved while pain, appetite loss, and systemic therapy side effects were reduced. Conclusions Use of the app enabled patients undergoing systemic therapy for early stage breast cancer to better cope with symptoms which was demonstrated by a better global quality of life and summary score after the first week and by a better summary score at the end of treatment in the intervention group compared to those of the control group, but no change in the use of health resources was demonstrated.

scholarly journals Mobile App for Symptom Management and Associated Quality of Life During Systemic Treatment in Early Stage Breast Cancer: Nonrandomized Controlled Prospective Cohort Study (Preprint)

2019 ◽  
Author(s):  
Cvetka Grašič Kuhar ◽  
Tjaša Gortnar Cepeda ◽  
Timotej Kovač ◽  
Matjaž Kukar ◽  
Nina Ružić Gorenjec
Keyword(s):  
Breast Cancer ◽  
Quality Of Life ◽  
Systemic Therapy ◽  
Early Stage ◽  
Intervention Group ◽  
Health Resources ◽  
Control Group ◽  
Global Quality ◽  
Global Quality Of Life

BACKGROUND Providing patients with cancer who are undergoing systemic therapy with useful information about symptom management is essential to prevent unnecessary deterioration of quality of life. OBJECTIVE The aim was to evaluate whether use of an app for symptom management was associated with any change in patient quality of life or use of health resources. METHODS Outpatients with early stage breast cancer receiving systemic therapy were recruited at the Institute of Oncology in Ljubljana, Slovenia. Patients who received systemic therapy between December 2017 and March 2018 (control group) and between April 2018 and September 2018 (intervention group) were eligible. All patients received standard care, but only those in the intervention group were asked to use mPRO Mamma, an Android-based smartphone app, in addition. The app supported daily tracking of 50 symptoms, allowed users to grade their symptom severity (as mild, moderate, or severe), and also provided in-depth descriptions and recommendations based on reported symptom level. Patient-reported outcomes in both groups were assessed through the European Organisation for Research and Treatment of Cancer (EORTC) core (C-30) and breast cancer (BR-23) questionnaires, as well as a questionnaire about health resources use. The primary outcomes were the difference in the global quality of life between groups and the difference in summary score of the EORTC C-30 questionnaire between groups after 3 time periods (the first week of treatment, the first treatment cycle, and the entire treatment). The secondary outcome was the use of health resources (doctor visits and hospitalizations) in each time period. Other scales were used for exploratory analysis. RESULTS The mean difference between the intervention group (n=46) and the control group (n=45) in global quality of life (adjusted for baseline and type of surgery) after the first week was 10.1 (95% CI 1.8 to 18.5, <i>P</i>=.02). The intervention group summary scores were significantly higher than those of the control group after the first week (adjusted mean difference: 8.9, 95% CI 3.1 to 14.7, <i>P</i>=.003) and at the end of treatment (adjusted mean difference: 10.6, 95% CI 3.9 to 17.3, <i>P</i>=.002). Use of health resources was not statistically significant between the groups in either the first week (<i>P</i>=.12) or the first treatment cycle (<i>P</i>=.13). Exploratory analysis findings demonstrated clinically important improvements (indicated by EORTC C-30 or BR-23 scale scores)—social, physical, role, and cognitive function were improved while pain, appetite loss, and systemic therapy side effects were reduced. CONCLUSIONS Use of the app enabled patients undergoing systemic therapy for early stage breast cancer to better cope with symptoms which was demonstrated by a better global quality of life and summary score after the first week and by a better summary score at the end of treatment in the intervention group compared to those of the control group, but no change in the use of health resources was demonstrated.

Impact of age-related socio-economic and clinical determinants of quality of life among long-term breast cancer survivors

Maturitas ◽  
2015 ◽  
Vol 81 (3) ◽  
pp. 362-370 ◽  
Author(s):  
Pegdwende Olivia Dialla ◽  
Wai-On Chu ◽  
Patrick Roignot ◽  
Marie-Christine Bone-Lepinoy ◽  
Marie-Laure Poillot ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Quality Of Life ◽  
Cancer Survivors ◽  
Breast Cancer Survivors ◽  
Age Related

Quality of life, fatigue and depression in Italian long-term breast cancer survivors

2012 ◽  
Vol 20 (11) ◽  
pp. 2941-2948 ◽  
Author(s):  
Francesca Romito ◽  
Claudia Cormio ◽  
Francesco Giotta ◽  
Giuseppe Colucci ◽  
Vittorio Mattioli
Keyword(s):  
Breast Cancer ◽  
Quality Of Life ◽  
Cancer Survivors ◽  
Breast Cancer Survivors

Quality of life of tunisian women after the treatment of breast cancer

2011 ◽  
Vol 26 (S2) ◽  
pp. 987-987
Author(s):  
L. Mnif ◽  
J. Masmoudi ◽  
N. Charfi ◽  
R. Damak ◽  
M. Guermazi ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Quality Of Life ◽  
General Population ◽  
Breast Cancer Survivors ◽  
University Hospital ◽  
Significant Deterioration ◽  
European Organization ◽  
Global Quality Of Life ◽  
Eortc Qlq

IntroductionIn Tunisia, the breast cancer is the most frequently diagnosed neoplasm in women.Objectives were to- Highlight the health-related QOL of Tunisian women after the treatment of breast cancer compared with the general population.- assess the functional scales that predict the global quality of life (GQOL) scale of the QLQ - C30.MethodsWe recruited 50 patients who were in remission for at least 3 months after initial treatment of breast cancer, and 50 women with no history of cancer.Those patients were previously referred to the Department of Gynecology in Sfax University Hospital for breast surgery, and then they had all received adjuvant therapy.QOL was evaluated using the Arabic version of the European Organization for Research and Treatment of Cancer (EORTC) QLQ-C30 questionnaire.ResultsThe mean scores for QLQ - C30 indicated that the patients had poor to average functioning (GQOL, 56.7; and five functional scales, 55.6%–67.3%).Those scores showed a significant deterioration in the sample of breast cancer survivors relative to general population.Among the symptoms scales, only the financial difficulties were significantly greater in patients (p = 9.10-7).Deterioration of the GQOL was induced by the worsening of the emotional (p = 0.005) and social (p = 0.008) functioning but it was independent of symptoms scales.ConclusionThe findings indicated that, despite many treatment advances, Tunisian women had significantly poorer GQOL and functional scales scores in comparison with the general population. It seems also that improving the emotional and social functioning contribute to a better GQOL.

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