scholarly journals A rare case of gastric-type mucinous endocervical adenocarcinoma in a 59-year-old woman

2020 ◽  
Vol 19 (3) ◽  
pp. 147-150
Author(s):  
Francesk Mulita ◽  
Fotios Iliopoulos ◽  
Ioannis Kehagias
Keyword(s):  
Rare Case ◽  
Endocervical Adenocarcinoma ◽  
Gastric Type

scholarly journals Gastric‐type endocervical adenocarcinoma and cervical cytology: Experience at a general hospital and review of the literature

Cytopathology ◽  
2020 ◽  
Vol 32 (1) ◽  
pp. 75-83
Author(s):  
Nancy Y. Greenland ◽  
Rebecca J. Wolsky ◽  
Teresa M. Darragh ◽  
Poonam Vohra
Keyword(s):  
General Hospital ◽  
Cervical Cytology ◽  
Review Of The Literature ◽  
Endocervical Adenocarcinoma ◽  
Gastric Type

Gastric‐type endocervical adenocarcinoma with uterine corpus involvement mimicking primary endometrial carcinoma

2019 ◽  
Vol 45 (7) ◽  
pp. 1414-1417 ◽  
Author(s):  
Akio Kamiya ◽  
Yoshihiro Ikura ◽  
Noriaki Iizuka ◽  
Toru Yokokawa ◽  
Hiroki Kato ◽  
...  
Keyword(s):  
Endometrial Carcinoma ◽  
Uterine Corpus ◽  
Endocervical Adenocarcinoma ◽  
Gastric Type

Ovarian Metastasis by Gastric-type Endocervical Adenocarcinoma

2021 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Bingjian Lu ◽  
Haiyan Shi ◽  
Ying Shao ◽  
Junfen Xu
Keyword(s):  
Ovarian Metastasis ◽  
Endocervical Adenocarcinoma ◽  
Gastric Type

scholarly journals Peuzt – Jeghers syndrome with gastric type mucinous endocervical adenocarcinoma in a young woman: A case report

2021 ◽  
pp. 102700
Author(s):  
Giap Vu Dinh ◽  
Nhat Doan Thi Hong ◽  
Tu Vo Ngoc ◽  
Long Nguyen Thanh ◽  
Hoai Hoang Thi ◽  
...  
Keyword(s):  
Case Report ◽  
Young Woman ◽  
Endocervical Adenocarcinoma ◽  
Gastric Type

scholarly journals Gastric-type Endocervical Adenocarcinoma

2015 ◽  
Vol 39 (11) ◽  
pp. 1449-1457 ◽  
Author(s):  
Yevgeniy S. Karamurzin ◽  
Takako Kiyokawa ◽  
Vinita Parkash ◽  
Anjali R. Jotwani ◽  
Prusha Patel ◽  
...  
Keyword(s):  
Endocervical Adenocarcinoma ◽  
Gastric Type

scholarly journals GASTRIC-TYPE ENDOCERVICAL ADENOCARCINOMA (GAS): A COMPARATIVE ANALYSIS

2019 ◽  
Author(s):  
Lenny Gallardo-Alvarado ◽  
David Cantu-de Leon ◽  
Rebeca Ramirez ◽  
Delia Perez-Montiel ◽  
Salim Abraham Barquet Muñoz ◽  
...  
Keyword(s):  
Comparative Analysis ◽  
Endocervical Adenocarcinoma ◽  
Gastric Type

scholarly journals A Retrospective Study on Incidence, Diagnosis, and Clinical Outcome of Gastric-type Endocervical Adenocarcinoma in a Single Institution

2021 ◽  
Author(s):  
Anna Radomska ◽  
Daniel Lee ◽  
Heather Neufeld ◽  
Nancy Korte ◽  
Emina Torlakovic ◽  
...  
Keyword(s):  
Human Papillomavirus ◽  
Kinase Inhibitor ◽  
P53 Protein ◽  
Progesterone Receptors ◽  
Cervical Adenocarcinoma ◽  
Single Institution ◽  
Mutant Type ◽  
Usual Type ◽  
Endocervical Adenocarcinoma ◽  
Gastric Type

Abstract Background: Gastric-type endocervical adenocarcinoma is rare but the most common subtype of cervical adenocarcinoma not associated with human papillomavirus. It is more aggressive with a shorter five-year survival rate compared to human papillomavirus-associated usual type endocervical adenocarcinoma. The objectives of our study were to determine the incidence and clinical-pathological characteristics of Gastric-type endocervical adenocarcinoma in a single institution. Methods: Twenty four cases of invasive cervical adenocarcinoma were identified between January 2000 and December 2015, from the Saskatoon Health Region pathology database using International Endocervical Adenocarcinoma Criteria and Classification to retrospectively classify endocervical adenocarcinoma. Immunohistochemistry was performed with antibodies for Gastric mucin-6 (MUC-6), p16INK4a, cyclin-dependent kinase inhibitor 2A (p16), p53 protein (p53), estrogen and progesterone receptors. Clinical and pathological data was retrieved from pathology reports and charts. Statistical analysis was performed using Mann-Whitney U test and Chi-Square test.Results: Using the International Endocervical Adenocarcinoma Criteria and Classification criteria, 19 cases (79.2%) were classified as human papillomavirus-associated usual type endocervical adenocarcinoma, and five cases (20.8%) as Gastric-type endocervical adenocarcinoma. In our study 40% of Gastric-type endocervical adenocarcinoma cases presented at stage III compared to none of the usual type endocervical carcinoma cases. All the Gastric-type endocervical adenocarcinoma cases were positive for MUC-6, and negative for p16. 60% Gastric-type endocervical adenocarcinoma cases demonstrated mutant type p53 staining. In contrast, 84.2% of human papillomavirus-associated usual type endocervical adenocarcinoma cases showed block like nuclear and cytoplasmic positivity with p16 antibodies. The Gastric-type endocervical adenocarcinoma group had significantly shorter median survival time than human papillomavirus-associated usual type endocervical adenocarcinoma group, Gastric-type endocervical adenocarcinoma is 22 months compared to human papillomavirus-associated usual type endocervical adenocarcinoma at 118 months (p = 0.043). Conclusions: In this study, Gastric-type endocervical adenocarcinoma accounted for 20.8% of all cervical adenocarcinoma with higher stage at presentation and shorter overall survival. Histomorphology and immunohistochemistry for MUC-6 and p16 could differentiate between Gastric-type endocervical adenocarcinoma and human papillomavirus-associated usual type endocervical adenocarcinoma.

Sign in / Sign up

Export Citation Format

Share Document