scholarly journals Influence of allergen immunotherapy on the quality of life in patients with asthma, allergic rhinitis and insect venom allergy

2018 ◽  
Vol 5 (3) ◽  
pp. 148-156
Author(s):  
Ewa Cichocka-Jarosz
Keyword(s):  
Quality Of Life ◽  
Allergic Rhinitis ◽  
Allergen Immunotherapy ◽  
Insect Venom Allergy ◽  
Venom Allergy ◽  
Insect Venom

scholarly journals Tolerability, course and follow-up of specific immunotherapy using a modified ultra-rush procedure in children and adolescents with insect venom allergy

2021 ◽  
Author(s):  
Jens-Oliver Steiß ◽  
Conrad Weber ◽  
Max Becker
Keyword(s):  
Quality Of Life ◽  
Quality Of Care ◽  
Maintenance Therapy ◽  
Children And Adolescents ◽  
Specific Immunotherapy ◽  
Insect Venom Allergy ◽  
Venom Allergy ◽  
Insect Venom

Summary Background Specific immunotherapy with insect venom (hymenoptera venom (HG)-AIT) is an effective and the only causal treatment for patients with systemic reactions due to IgE-mediated insect venom allergy. The present study investigated the quality of care after bee and wasp venom allergy, the tolerability of modified ultra-rush immunotherapy and the course after the conclusion of maintenance therapy in children and adolescents. Studies on the quality of life of children with insect venom allergy are scarce. Methods The efficacy, safety and tolerability of an ultra-rush protocol was analysed in 114 patients aged 4–17 years with insect venom allergy. After the end of HG-AIT, patients were contacted by questionnaire and asked to report on the quality of care as well as the course of insect venom allergy, including accidental stinging events. Quality of life was validated using the established questionnaire VQLQ‑d (Vespid Quality of Life Questionnaire), which is also used for bee venom allergy patients. Results Discontinuation of the initial therapy was not necessary in any patient. Side effects were mostly mild and did not require treatment. In 16 patients, a new sting reaction occurred during maintenance therapy, in another 15 patients a sting event was documented after cessation of HG-AIT. The intensity of the reaction to the accidental insect bite according to the severity classification after Ring and Messmer decreased from an average of 2.3 to 0.9 in these patients. This corresponds to a decrease of 61%. An emergency kit was carried by 70% of the patients, the expiry date of which, however, had already passed in almost 40% of the respondents. After the end of the therapy, most patients were not under any medical care or had never been to a check-up (92%). The evaluation of the VQLQ‑d showed a medium to low level of stress during or after therapy. Discussion Ultra-rush AIT in childhood and adolescence is safe, tolerable and effective. HG-AIT has a lasting positive effect on the health-related quality of life of patients. However, after the end of HG-AIT, there are deficits in the follow-up and care of the patients.

Allergic rhinitis and quality of life after one year of allergen immunotherapy

2002 ◽  
Vol 109 (1) ◽  
pp. S121-S121
Author(s):  
S Echechipia ◽  
BE Garcia ◽  
MT Lizaso ◽  
MT Aldunate ◽  
JM Olaguibel ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Allergic Rhinitis ◽  
Allergen Immunotherapy ◽  
One Year

scholarly journals Allergen immunotherapy for insect venom allergy: protocol for a systematic review

2015 ◽  
Vol 6 (1) ◽  
Author(s):  
Sangeeta Dhami ◽  
Ulugbek Nurmatov ◽  
Eva-Maria Varga ◽  
Gunter Sturm ◽  
Antonella Muraro ◽  
...  
Keyword(s):  
Systematic Review ◽  
Allergen Immunotherapy ◽  
Insect Venom Allergy ◽  
Venom Allergy ◽  
Insect Venom

scholarly journals Erratum to: Allergen immunotherapy for insect venom allergy: protocol for a systematic review

2017 ◽  
Vol 7 (1) ◽  
Author(s):  
Sangeeta Dhami ◽  
Ulugbek Nurmatov ◽  
Eva-Maria Varga ◽  
Gunter Sturm ◽  
Antonella Muraro ◽  
...  
Keyword(s):  
Systematic Review ◽  
Allergen Immunotherapy ◽  
Insect Venom Allergy ◽  
Venom Allergy ◽  
Insect Venom

Long-term efficacy of injected allergen immunotherapy for treatment of grass pollen allergy in elderly patients with allergic rhinitis

2020 ◽  
Vol 41 (4) ◽  
pp. 271-277
Author(s):  
Andrzej Bozek ◽  
Anna Cudak ◽  
Giorgio Walter Canonica
Keyword(s):  
Quality Of Life ◽  
Allergic Rhinitis ◽  
Placebo Group ◽  
Elderly Patients ◽  
Grass Pollen ◽  
Allergen Immunotherapy ◽  
Pollen Allergy ◽  
Life Questionnaire ◽  
Grass Pollen Allergy

Background: The effect of prolonged allergen immunotherapy is still insufficiently known, especially in elderly patients. Objective: The effect after a 3-year course of injected allergen-specific immunotherapy (AIT) for grass pollen allergy in elderly patients with allergic rhinitis was observed. Methods: Thirty-eight elderly patients (mean ± standard deviation, 66.2 ± 2.7 years old) who received preseasonal injected AIT or placebo for grass pollen allergy were monitored for 3 years and compared with a placebo group. The combined symptom medication score (CSMS), serum level of immunoglobulin G4 (IgG4) to phleum pratense 5 (Phl p5) and quality of life were assessed immediately after AIT and 3 years later. Results: After AIT, the CSMS was significantly decreased from 2.15 (range, 1.27‐3.00) to 1.13 (range, 0.79‐1.36) (p = 0.03) and remained lower (1.41 ± 0.72 versus 2.41 ± 1.11) than that in the placebo group during the 3 years after AIT. Serum-specific IgG4 against increased during the course of AIT and remained at a high level during further observation. Quality of life, based on the Rhinoconjunctivitis Quality of Life Questionnaire, was significantly decreased in the patients who received AIT from 1.51 (95% confidence interval [CI], 1.21‐1.84) to 1.01 (95% CI, 0.93‐1.87) (p < 0.05) and was decreased to 0.97‐1.26 (95% CI, 0.88‐1.82) during the 3 years after discontinuation of AIT. Conclusion: A prolonged positive effect after AIT for grass pollen allergy was observed in elderly patients with allergic rhinitis. Further trials are needed to confirm this effect.Clinical trial MC56871/12, <ext-link xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="uri" xlink:href="http://www.clinicaltrials.gov">www.clinicaltrials.gov</ext-link>.

scholarly journals Allergen immunotherapy for insect venom allergy: a systematic review and meta-analysis

Allergy ◽  
2017 ◽  
Vol 72 (3) ◽  
pp. 342-365 ◽  
Author(s):  
S. Dhami ◽  
H. Zaman ◽  
E.-M. Varga ◽  
G. J. Sturm ◽  
A. Muraro ◽  
...  
Keyword(s):  
Systematic Review ◽  
Allergen Immunotherapy ◽  
Meta Analysis ◽  
Insect Venom Allergy ◽  
Venom Allergy ◽  
Insect Venom
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