scholarly journals Role of topical combination drug containing clindamycin and benzoyl peroxide 279 in the treatment of common acne

2012 ◽  
Vol 4 ◽  
pp. 279-292
Author(s):  
Marta Pastuszka ◽  
Andrzej Kaszuba
Keyword(s):  
Benzoyl Peroxide ◽  
Combination Drug

Elucidation of block boundaries as the dissolution channels in hydrated cement

1978 ◽  
Vol 36 (1) ◽  
pp. 484-485
Author(s):  
N.V. Belov ◽  
U.I. Papiashwili ◽  
B.E. Yudovich
Keyword(s):  
Liquid Phase ◽  
Grain Boundaries ◽  
Benzoyl Peroxide ◽  
Phase Contrast ◽  
Active Role ◽  
Point Of View ◽  
Hardened Cement ◽  
Hydrated Cement ◽  
Hardened Cement Paste

It has been almost universally adopted that dissolution of solids proceeds with development of uniform, continuous frontiers of reaction.However this point of view is doubtful / 1 /. E.g. we have proved the active role of the block (grain) boundaries in the main phases of cement, these boundaries being the areas of hydrate phases' nucleation / 2 /. It has brought to the supposition that the dissolution frontier of cement particles in water is discrete. It seems also probable that the dissolution proceeds through the channels, which serve both for the liquid phase movement and for the drainage of the incongruant solution products. These channels can be appeared along the block boundaries.In order to demonsrate it, we have offered the method of phase-contrast impregnation of the hardened cement paste with the solution of methyl metacrylahe and benzoyl peroxide. The viscosity of this solution is equal to that of water.

Compendium of Conventional and Targeted Drug Delivery Formulation Used for the Treatment and Management of the Wound Healing

2021 ◽  
Vol 18 ◽  
Author(s):  
Ajay Singh ◽  
Zeba Maqsood ◽  
Mohammad Kashif Iqubal ◽  
Javed Ali ◽  
Sanjula Baboota
Keyword(s):  
Drug Delivery ◽  
Wound Healing ◽  
Healing Process ◽  
Wound Healing Process ◽  
Combination Drug ◽  
Delayed Wound Healing ◽  
Accelerate Wound Healing ◽  
Synthetic Drugs ◽  
Normal Wound Healing

: Wound healing is a complex and dynamic phenomenon that involves the restoration of normal physiology and functioning of injured tissue. The process of wound healing is primarily regulated by various cytokines, inflammatory mediators, and growth factors at the molecular level. Any intervention in the normal wound healing process leads to further tissue damage, which in turn leads to delayed wound healing. Several natural, synthetic drugs and their combinations were used to restored and accelerate the wound healing process. However, the conventional delivery carriers were not much effective, and thus, nowadays, nanocarriers are gaining much popularity since they are playing a pivotal role in drug delivery. Since nanocarriers have their own applicability and benefits (enhance the bioavailability, site-specific targeting) so, they can accelerate wound healing more efficiently. This review briefly discussed about the various events that take place during the wound healing process with emphasis on various natural, synthetic, and combination drug therapy used for accelerating wound healing and the role of nanotechnology-based approaches in chronic wound healing.

The Role of Free Radicals in Low Temperature Vulcanization of Butadiene Rubber

1960 ◽  
Vol 33 (1) ◽  
pp. 199-207
Author(s):  
B. A. Dogadkin ◽  
E. N. Belyaeva
Keyword(s):  
Hydrogen Sulfide ◽  
Low Temperature ◽  
Benzoyl Peroxide ◽  
Spectroscopic Analysis ◽  
Elementary Sulfur ◽  
Butadiene Rubber ◽  
Radical Chain ◽  
Considerable Loss ◽  
Chain Interaction

Abstract 1. Elementary sulfur, liberated in the nascent state at room temperature in the reactions of MBTS with H2S, of benzoyl peroxide with H2S and SO2 with H2S, does not bring about vulcanization of butadiene rubber. In the case of the system MBTS/H2S we observe combination of sulfur in amounts 1.2 to 1.6% to a small portion of the rubber, which does not lead to structurization. The main part of the rubber (about 90% by weight) does not, according to spectroscopic analysis, alter. The combination of sulfur with rubber observed in this case takes place, apparently, according to an ionic mechanism. 2. Low-temperature vulcanization (structurization) of rubber by the system MBTS/H2S becomes apparent with prior irradiation of solutions of rubber containing disulfide with diffuse or ultraviolet light. The rate of structurization depends upon the duration of irradiation and is governed by the interaction with the H2S of the polymeric rubber radicals which are formed as a result of the dehydrogenation of the rubber by the benzothiazolyl radicals which are formed in the photodissociation of the disulfide. 3. Structurization of rubber by the system benzoyl peroxide/hydrogen sulfide is observed in the presence of an amine, in particular PBNA, necessary for the formation of free benzoate radicals as a result of the reaction of the peroxide with the amine. The peroxide in the present case acts similarly to the benzothiazolyl radicals in the case of the system MBTS/H2S. 4. Peachey type low-temperature vulcanization (SO2/H2S) proceeds in the presence of the peroxides of the rubber itself. Prior heating of the solutions of rubber upsets structurization. 5. In the vulcanization of rubber by the systems MBTS/H2S and benzoyl peroxide/hydrogen sulfide we observe combination of sulfur with the rubber in amounts of 0.6 to 0.7% and a considerable loss of double bonds, reaching 60% for 1:4 type bonds and 75% for 1:2 type bonds. 6. Radical chain interaction schemes are put forward for the processes of low-temperature structurization (vulcanization) of rubber under the action of the systems MBTS/H2S, benzoyl peroxide/hydrogen sulfide and SO2/H2S. 7. The reaction of benzoyl peroxide with PBNA is studied. A new compound, O-benzoyl-N-phenyl-N-2-naphthylhydroxylamine, is obtained, which is a powerful inhibitor of rubber oxidation.

The role of oxygen in the reaction of ferrocene with benzoyl peroxide

2015 ◽  
Vol 85 (1) ◽  
pp. 123-125 ◽  
Author(s):  
Yu. I. Murinov ◽  
S. A. Grabovskiy ◽  
A. R. Kuramshina ◽  
A. V. Antipin ◽  
N. N. Kabal’nova
Keyword(s):  
Benzoyl Peroxide

Adjuvant chemotherapy in stage III and IV squamous cell carcinoma of the head and neck

1988 ◽  
Vol 102 (4) ◽  
pp. 337-340 ◽  
Author(s):  
A. Klima ◽  
TH Klippstein ◽  
L. Bergmann ◽  
S. Szepesi ◽  
C. V. Ilberg
Keyword(s):  
Head And Neck ◽  
Tumour Response ◽  
Multimodality Treatment ◽  
Drug Regimen ◽  
Stage Iii ◽  
Combination Drug ◽  
Radiotherapy Group ◽  
Group I ◽  
Group Ii

Summary Initial combination drug regimen containing cisplatin in patients with stage III and IV head and neck cancer produced a high percentage of clinical response. This trial was initiated to assess the role of multimodality treatment (chemotherapy plus radiotherapy) versus chemotherapy alone. Ninety-six patients entered into this study; 80 patients were evaluable at time of analysis (Table I). Patients were randomized between chemotherapy and radiotherapy (group I) and chemotherapy alone (group II). The chemotherapy administered consisted of cisplatin, bleomycin and methotrexate and was given in 2 cycles over 35 days. Local radiotherapy followed. In group II 3 cycles of chemotherapy were given without radiotherapy. The overall tumour response after chemotherapy rose up to 75 per cent. After radiotherapy in group II the response rate sank to 59 per cent. In both regimes the remission duration was very short. Patients receiving only two cycles of chemotherapy do not have a statistically shorter survival than patients, who were treated by chemotherapy plus radiotherapy, or by a 3rd cycle of chemotherapy.

Polymerization of vinyl chloride by the AlEt3/benzoyl-peroxide/Lewis-base system and the role of the Lewis base in initiation

Polymer ◽  
1972 ◽  
Vol 13 (6) ◽  
pp. 288-296 ◽  
Author(s):  
E.B. Milovskaya ◽  
E.L. Kopp ◽  
O.S. Mikhailicheva ◽  
V.M. Denisov ◽  
A.I. Koltsov
Keyword(s):  
Benzoyl Peroxide ◽  
Vinyl Chloride ◽  
Lewis Base ◽  
Base System
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