scholarly journals Differences in retinal vascular parameters between pediatric patients with inflammatory bowel diseases and healthy controls measured by optical coherence tomography angiography

Klinika Oczna ◽  
2020 ◽  
Vol 122 (3) ◽  
pp. 100-104
Author(s):  
Beata Klincewicz ◽  
Andrzej Michalski ◽  
Marcin Stopa
Keyword(s):  
Optical Coherence Tomography ◽  
Inflammatory Bowel Diseases ◽  
Optical Coherence Tomography Angiography ◽  
Pediatric Patients ◽  
Healthy Controls ◽  
Optical Coherence ◽  
Bowel Diseases ◽  
Inflammatory Bowel

Tu1718 - Body Image Dissatisfaction in Pediatric Patients with Inflammatory Bowel Diseases

2018 ◽  
Vol 154 (6) ◽  
pp. S-998
Author(s):  
Jennifer Claytor ◽  
Bharati Kochar ◽  
Michael Kappelman ◽  
Christopher Martin ◽  
Amber Robb ◽  
...  
Keyword(s):  
Body Image ◽  
Inflammatory Bowel Diseases ◽  
Pediatric Patients ◽  
Body Image Dissatisfaction ◽  
Bowel Diseases ◽  
Inflammatory Bowel

Dermatological Manifestations in Pediatric Patients with Inflammatory Bowel Diseases on Anti-TNF Therapy

2018 ◽  
Vol 24 (9) ◽  
pp. 2086-2092 ◽  
Author(s):  
Shilpa Sridhar ◽  
Ross M Maltz ◽  
Brendan Boyle ◽  
Sandra C Kim
Keyword(s):  
Inflammatory Bowel Diseases ◽  
Pediatric Patients ◽  
Bowel Diseases ◽  
Inflammatory Bowel

Assessment of optic nerve head parameters using optical coherence tomography angiography in behçet uveitis patients with healthy controls

2020 ◽  
Vol 29 (2) ◽  
pp. 131
Author(s):  
Melike BALIKOGLU ◽  
Erdinc AYDIN ◽  
Pinar NALCACIOGLU ◽  
Nur DOGANAY KUMCU ◽  
Seher SARITEPE IMREL ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Optic Nerve ◽  
Optic Nerve Head ◽  
Optical Coherence Tomography Angiography ◽  
Healthy Controls ◽  
Optical Coherence

scholarly journals P015 BODY IMAGE DISSATISFACTION IN PEDIATRIC PATIENTS WITH INFLAMMATORY BOWEL DISEASES

2018 ◽  
Vol 24 (suppl_1) ◽  
pp. S6-S6
Author(s):  
Jennifer Claytor ◽  
Bharati Kochar ◽  
Michael Kappelman ◽  
Christopher F Martin ◽  
Amber Robb ◽  
...  
Keyword(s):  
Body Image ◽  
Inflammatory Bowel Diseases ◽  
Pediatric Patients ◽  
Body Image Dissatisfaction ◽  
Bowel Diseases ◽  
Inflammatory Bowel

scholarly journals Optical coherence tomography angiography indicates subclinical retinal disease in neuromyelitis optica spectrum disorders

2021 ◽  
pp. 135245852110288
Author(s):  
Lilian Aly ◽  
Eva-Maria Strauß ◽  
Nikolaus Feucht ◽  
Isabella Weiß ◽  
Achim Berthele ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
Optical Coherence Tomography ◽  
Optic Neuritis ◽  
Disease Activity ◽  
Optical Coherence Tomography Angiography ◽  
Visual Performance ◽  
Healthy Controls ◽  
Optical Coherence ◽  
Neuromyelitis Optica Spectrum Disorders ◽  
Spectrum Disorders

Background: Neuromyelitis optica spectrum disorders (NMOSD) are neuroinflammatory diseases of the central nervous system. Patients suffer from recurring relapses and it is unclear whether relapse-independent disease activity occurs and whether this is of clinical relevance. Objective: To detect disease-specific alterations of the retinal vasculature that reflect disease activity during NMOSD. Methods: Cross-sectional analysis of 16 patients with NMOSD, 21 patients with relapsing-remitting multiple sclerosis, and 21 healthy controls using retinal optical coherence tomography (OCT), optical coherence tomography angiography (OCT-A), measurement of glial fibrillary acidic protein (GFAP) serum levels, and assessment of visual acuity. Results: Patients with NMOSD but not multiple sclerosis revealed lower foveal thickness (FT) ( p = 0.02) measures and an increase of the foveal avascular zone (FAZ) ( p = 0.02) compared to healthy controls independent to optic neuritis. Reduced FT ( p = 0.01), enlarged FAZ areas ( p = 0.0001), and vessel loss of the superficial vascular complex ( p = 0.01) were linked to higher serum GFAP levels and superficial vessel loss was associated with worse visual performance in patients with NMOSD irrespective of optic neuritis. Conclusion: Subclinical parafoveal retinal vessel loss might occur during NMOSD and might be linked to astrocyte damage and poor visual performance. OCT-A may be a tool to study subclinical disease activity during NMOSD.

scholarly journals Going Viral: a Novel Role for Bacteriophage in Colorectal Cancer

mBio ◽  
2019 ◽  
Vol 10 (1) ◽  
Author(s):  
Scott A. Handley ◽  
Suzanne Devkota
Keyword(s):  
Colorectal Cancer ◽  
Dark Matter ◽  
Gastrointestinal Tract ◽  
Sample Preparation ◽  
Cross Section ◽  
Inflammatory Bowel Diseases ◽  
Healthy Controls ◽  
Bowel Diseases ◽  
Inflammatory Bowel ◽  
Disease Signatures

ABSTRACT Microbiome-based signatures of disease have focused primarily on the bacterial component of the microbiome for numerous reasons, including ease of sample preparation and depth of the curated bacterial database. However, even more numerous than bacteria are the bacteriophages of the viral portion of the microbiome, which have emerged with identifiable disease signatures in other diseases, such as inflammatory bowel diseases. Here, G. D. Hannigan, M. B. Duhaime, M. T. Ruffin, IV, C. C. Koumpouras, and P. D. Schloss (mBio 9:e02248-18, https://doi.org/10.1128/mBio.02248-18) present a study that explores the potential bacteriophage signatures in patients with colorectal cancer (CRC) and the associated changes in bacterial signatures. Sampling from a cross section of 60 patients at different stages of CRC in addition to 30 healthy controls, this study highlights the need for greater exploration into the virome, including the “dark matter” of diverse forms that viruses assume in the gastrointestinal tract.

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