scholarly journals Interobserver variations of target volume delineation and its impact on irradiated volume in accelerated partial breast irradiation with intraoperative interstitial breast implant

2017 ◽  
Vol 2 ◽  
pp. 139-145 ◽  
Author(s):  
Ritu Raj Upreti ◽  
Ashwini Budrukkar ◽  
Tabassum Wadasadawala ◽  
Shagun Misra ◽  
Lavanya Gurram ◽  
...  
Keyword(s):  
Breast Implant ◽  
Target Volume ◽  
Accelerated Partial Breast Irradiation ◽  
Partial Breast Irradiation ◽  
Breast Irradiation ◽  
Target Volume Delineation ◽  
Volume Delineation ◽  
Interobserver Variations

Target volume delineation in external beam partial breast irradiation: Less inter-observer variation with preoperative- compared to postoperative delineation

2014 ◽  
Vol 110 (3) ◽  
pp. 467-470 ◽  
Author(s):  
Femke van der Leij ◽  
Paula H.M. Elkhuizen ◽  
Tomas M. Janssen ◽  
Philip Poortmans ◽  
Maurice van der Sangen ◽  
...  
Keyword(s):  
Target Volume ◽  
Observer Variation ◽  
Partial Breast Irradiation ◽  
External Beam ◽  
Breast Irradiation ◽  
Target Volume Delineation ◽  
Volume Delineation

PO-0625 EXTERNAL BEAM PARTIAL BREAST IRRADIATION: DIFFERENCE IN PRE-AND POSTOPERATIVE TARGET VOLUME DELINEATION

2012 ◽  
Vol 103 ◽  
pp. S246 ◽  
Author(s):  
F. van der Leij ◽  
P.H.M. Elkhuizen ◽  
T.M. Janssen ◽  
P. Poortmans ◽  
M. van der Sangen ◽  
...  
Keyword(s):  
Target Volume ◽  
Partial Breast Irradiation ◽  
External Beam ◽  
Breast Irradiation ◽  
Target Volume Delineation ◽  
Volume Delineation

Five-day accelerated partial breast irradiation (APBI) using intensity modulated radiation therapy (IMRT) in stage 0-II breast cancer: A report of 214 cases with up to 39 month follow-up.

2021 ◽  
Vol 39 (15_suppl) ◽  
pp. e12508-e12508
Author(s):  
Rufus J. Mark ◽  
Valerie Gorman ◽  
Michal Wolski ◽  
Steven McCullough
Keyword(s):  
Breast Cancer ◽  
Intensity Modulated Radiation Therapy ◽  
Target Volume ◽  
Accelerated Partial Breast Irradiation ◽  
Partial Breast Irradiation ◽  
Breast Irradiation ◽  
Skin Reactions ◽  
Cosmetic Results ◽  
Non Invasive

e12508 Background: Randomized trials in stage 0-II breast cancer have proven that APBI given via HDR implant in 5 days is equivalent to whole breast irradiation (WBI) given in 5-6 weeks in regard to breast tumor local recurrence (LR). However, complications have been significant. Recently APBI using non-invasive IMRT given in 5 fractions has been shown in another randomized trial with 10 year follow-up to be equivalent to WBI in 6 weeks, with respect to LR. IMRT was superior in regard to acute effects, late effects, and cosmesis. In the randomized clinical trial of APBI IMRT, the Clinical Target Volume (CTV) was defined by the injection of individual fiducial markers bordering the surgical cavity. We have used the Biozorb fiducial system to localize the CTV for IMRT. We sought to confirm the APBI IMRT results with this simpler less labor intensive fiducial placement system. Methods: Between 2017 and 2021, 214 patients have undergone IMRT targeted to a Biozorb defined CTV with the walls of the surgical cavity sewn to the Biozorb device. Eligible patients were older than age 40, had tumor sizes < 3 cm, negative surgical margins, and negative sentinel node dissections. IMRT dose was 30 Gy given in 5 fractions. Dose Constraints were as follows : V-30 Gy < 105%, Ipsilateral Breast V-15 Gy < 50%, Ipsilateral Lung V-10 Gy < 20%, Contralateral Lung V-5 Gy < 10%, Heart V-3 Gy < 20%, Contralateral Breast Dmax < 2 Gy and Skin Dmax < 27 Gy. The Planning Target Volume (PTV) ranged from 27 to 355 cc with a median of 80 cc. PTV = CTV + 1-2 cm. Results: Follow-up ranged from 1-39 months with a median of 20 months. LR has been 0% (0/214). There have been no skin reactions or seromas. Infection has occurred in one patient (0.5%). Four (1.9%) patients developed pain around the Biozorb site. This resolved on a short courses of steroids in all cases. Cosmetic results as rated by the Surgeon, Radiation Oncologist, and Nurse, were rated excellent in 99.0% (212/214) of cases. Conclusions: Non-invasive APBI with IMRT given qd over 5 days targeted to Biozorb has resulted in LR, complications, and cosmetic results which compare favorably to invasive APBI given bid with HDR implant. At last follow-up, there have been no LR, skin reactions, or significant complications. Cosmesis has been excellent in 99.0% of patients.

Multicatheter breast implant during breast conservative surgery: Novel approach to deliver accelerated partial breast irradiation

Brachytherapy ◽  
2016 ◽  
Vol 15 (4) ◽  
pp. 485-494 ◽  
Author(s):  
Mauricio Cambeiro ◽  
Fernando Martinez-Regueira ◽  
Natalia Rodriguez-Spiteri ◽  
Begoña Olartecoechea ◽  
Luis Pina Insausti ◽  
...  
Keyword(s):  
Breast Implant ◽  
Conservative Surgery ◽  
Accelerated Partial Breast Irradiation ◽  
Partial Breast Irradiation ◽  
Breast Irradiation ◽  
Breast Conservative Surgery ◽  
Novel Approach
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