scholarly journals Original article Methyl-CpG binding protein 2, receptors of innate immunity and receptor for advanced glycation end-products in human viral meningoencephalitis

2014 ◽  
Vol 4 ◽  
pp. 428-435
Author(s):  
Danuta Maslinska ◽  
Milena Laure-Kamionowska ◽  
Sławomir Maslinski
Keyword(s):  
Innate Immunity ◽  
Advanced Glycation End Products ◽  
Binding Protein ◽  
Advanced Glycation ◽  
Glycation End Products ◽  
End Products

The Emerging Role of the Receptor for Advanced Glycation End Products on Innate Immunity

2013 ◽  
Vol 33 (1) ◽  
pp. 67-80 ◽  
Author(s):  
Armando Rojas ◽  
Ramón Pérez-Castro ◽  
Ileana González ◽  
Fernando Delgado ◽  
Jacqueline Romero ◽  
...  
Keyword(s):  
Innate Immunity ◽  
Advanced Glycation End Products ◽  
Advanced Glycation ◽  
Glycation End Products ◽  
End Products

Identification of C1q as a Binding Protein for Advanced Glycation End Products

Biochemistry ◽  
2016 ◽  
Vol 55 (3) ◽  
pp. 435-446 ◽  
Author(s):  
Miho Chikazawa ◽  
Takahiro Shibata ◽  
Yukinori Hatasa ◽  
Sayumi Hirose ◽  
Natsuki Otaki ◽  
...  
Keyword(s):  
Advanced Glycation End Products ◽  
Binding Protein ◽  
Advanced Glycation ◽  
Glycation End Products ◽  
End Products

scholarly journals Co-localization of the Receptor for Advanced Glycation End Products (RAGE) with S100 Calcium-Binding Protein B (S100B) in Human Umbilical Vein Endothelial

2019 ◽  
Vol 63 (1) ◽  
Author(s):  
Iris Serratos ◽  
Ambar López_Macay ◽  
Pilar Castellanos ◽  
José Gilberto Córdoba-Herrera ◽  
Ruy Pérez-Montfort ◽  
...  
Keyword(s):  
Advanced Glycation End Products ◽  
Calcium Binding ◽  
Binding Protein ◽  
Umbilical Vein ◽  
Calcium Binding Protein ◽  
Advanced Glycation ◽  
Human Umbilical Vein ◽  
S100 Calcium Binding Protein ◽  
Glycation End Products ◽  
End Products

The receptor for advanced glycation end products (RAGE) has been involved in the actions of inflammatory proteins such as S100 calcium binding protein B (S100B), among several others. Despite there being many studies available proposing several different modes of interaction between the receptor and the protein, it is necessary to reconcile these binding hypotheses. We evaluated the co-localization of RAGE and S100B in human umbilical vein endothelial cells (HUVEC’s) exposed to acute pro-inflammatory lipopolysaccharide (LPS). Co-localization of the receptor and the protein in umbilical cells exposed to pro-inflammatory stimuli was analyzed using an immunofluorescent assay. RAGE was present in umbilical cells, and its co-localization with S100B was stimulated in the presence of LPS. Our findings suggest an interaction between these proteins, possibly producing early inflammatory responses in umbilical cells. The understanding of the molecular mechanisms of this recognition is relevant to characterize the nature of the signaling associated with this receptor in inflammatory processes.

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