scholarly journals Severe cicatricial alopecia as a rare cutaneous side effect due to erlotinib – case report

2016 ◽  
Vol 5 ◽  
pp. 371-375
Author(s):  
Magdalena Żychowska ◽  
Aleksandra Batycka-Baran ◽  
Wojciech Baran ◽  
Joanna Maj
Keyword(s):  
Case Report ◽  
Side Effect ◽  
Cutaneous Side Effect

scholarly journals Cutaneous Side Effect of Hydroxurea in a Sickle Cell Anaemia Child-A Case Report

2019 ◽  
pp. 1-6
Author(s):  
A. O. Salako ◽  
S. O. Ogunmefun ◽  
O. W. Aworanti
Keyword(s):  
Case Report ◽  
Side Effects ◽  
Sickle Cell ◽  
Side Effect ◽  
Low Dose ◽  
Sickle Cell Anaemia ◽  
Skin Lesions ◽  
Cutaneous Lesions ◽  
Care Givers ◽  
Cutaneous Side Effect

Background: Hydroxyurea (HU) has redefined the quality of life of children with sickle cell anaemia and their care givers. Despite the acclaimed benefits of HU, the drug could be associated with variable side effects affecting different systems in the human body, including the skin and integuments. The aim of this report is to raise the awareness about the less common side effects of HU. Case Report: A 5-year 8 months old homozygous sickle cell anaemia child presented with pruritic hyperpigmented lesions on the trunk, arms and the legs, four weeks after commencement of HU. HU was initially discontinued for two weeks and thereafter recommenced with a different brand but there was worsening skin lesions despite at a daily low dose of 10 mg/kg. The rashes eventually resolved with low dose once in 3 days HU therapy.  She had recurrent episodes of acute painful crisis; average of three [3] episodes per year warranted hospital admission prior to commencement, but with HU therapy, there has been significant improvement in the crisis. Discussion: Cutaneous lesions are uncommon side effect of hydroxyurea. This side effect is dependent on genetic predisposition and photosensitivity. However, with the established benefit of HU in the management sickle cell anaemia, it is important for the sickle cell experts to continue to monitor closely the children for both the common and rare side effects and to individualize therapy to ensure maximal benefit with minimal or no side effects.

Methimazole induced agranulocytosis side effect-not always a bad effect: case report

2016 ◽  
Author(s):  
Iulia Soare ◽  
Anca Sirbu ◽  
Minodora Betivoiu ◽  
Simona Fica
Keyword(s):  
Case Report ◽  
Side Effect

Skin lesions and G-CSF in patients with malignant diseases. Malignancy or cutaneous side-effect?

1996 ◽  
Vol 32 (3) ◽  
pp. 554-555 ◽  
Author(s):  
A. Loraas ◽  
S.D. Fossa ◽  
S. Franzen ◽  
G. S˦ter ◽  
L. Rode
Keyword(s):  
Side Effect ◽  
Skin Lesions ◽  
Malignant Diseases ◽  
Cutaneous Side Effect

scholarly journals Bleomycin-induced flagellate pigmentation: a case report from North-East India

2019 ◽  
Vol 5 (4) ◽  
pp. 879
Author(s):  
Nandakishore Thokchom ◽  
Nandita Bhattacharjee ◽  
Linda Kongbam
Keyword(s):  
Adverse Effect ◽  
Case Report ◽  
Germ Cell ◽  
Targeted Therapies ◽  
Side Effect ◽  
Ovarian Teratoma ◽  
Germ Cell Tumours ◽  
North East India ◽  
North East ◽  
Cutaneous Adverse Effect

<p class="abstract">Bleomycin is an antitumour antibiotic commonly used in the management of Hodgkin’s lymphoma and germ cell tumours. Flagellate pigmentation is a very specific and rare cutaneous adverse effect of bleomycin. It is characterised by linear, painless, pruritic, hyperpigmented lesions simulating marks of whiplashes over trunk and extremities. With the advent of targeted therapies resulting in the infrequent use of bleomycin, this unique side effect is also uncommonly encountered nowadays. Here, we report a case of bleomycin-induced flagellate pigmentation in a 35-year-old Indian female with ovarian teratoma. The characteristic patterned hyperpigmented patches developed following 2nd cycle of chemotherapy with bleomycin, etoposide and cisplatin.</p><p class="abstract"> </p>

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