Evaluation of the efficacy and tolerability of mandelic acid-containing cosmetic formulations for acne skin care

In vitro techniques to assess the proficiency of skin care cosmetic formulations

Pharmacognosy Reviews ◽

10.4103/0973-7847.120507 ◽

2013 ◽

Vol 7 (14) ◽

pp. 97 ◽

Cited By ~ 13

Author(s):

RamKumar Sahu ◽

Munglu Matlam ◽

VinayKumar Deshmukh ◽

Jaya Dwivedi ◽

ArvindKumar Jha ◽

...

Keyword(s):

Skin Care ◽

In Vitro Techniques ◽

Cosmetic Formulations

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Evaluation of comedogenic potential of a paraben-free plant-based butter moisturizing cream: A double-blind, comparative study

10.25259/csdm_53_2021 ◽

2021 ◽

Vol 1 ◽

pp. 52

Author(s):

Monil Yogesh Neena Gala ◽

Snehal Sameer Muchhala ◽

Sujeet Narayan Charugulla ◽

Rahul Rathod ◽

Amey Mane ◽

...

Keyword(s):

Comparative Study ◽

Coconut Oil ◽

Critical Factor ◽

Positive Control ◽

Negative Control ◽

Skin Care ◽

Double Blind ◽

Test Product ◽

Cosmetic Formulations ◽

The Mean

Objectives: Comedogenicity is a critical factor in making of cosmetics and skin care products. The term “acne cosmetica” was coined to link the relationship between female acne to the use of cosmetic formulations, stating that the ingredients used in the cosmetic formulations have the potential to evoke a comedogenic response or produce comedones. Therefore, it is important that a skin care product is non-comedogenic and efficacious at the same time. The main objective of this study is to evaluate the comedogenic potential of the test product (Venusia Max Cream – paraben free) when applied topically under occluded patch to the skin. Material and Methods: This was a randomized, double-blinded, comparative study conducted in 24 healthy female participants, with prominent follicular orifices on the upper back region. Comedogenic potential of the test product (Venusia Max Cream – paraben free) was evaluated in comparison to positive (coconut oil) and negative (glycerin) controls in women. Each participant received topical application of test and control products under occluded patch to the skin on the upper aspect of the back, 3 times weekly for 4 weeks. Cyanoacrylate biopsies were performed before and after treatment to determine the microcomedones histologically. Microcomedones were graded using light microscopy and results were analyzed based on scale rating (0–3). Results: The mean comedone grading was assessed between positive versus negative control, and positive control versus test product. The mean comedone grades were significantly less in test product 0.41 ± 0.50 and negative control 0.82 ± 0.73 in comparison to positive control 2.09 ± 0.68. The test product was least comedogenic in this study. Furthermore, no adverse events were reported during the study period. Conclusion: Based on the histological evidence, Venusia Max Cream (paraben free) is a non-comedogenic, plant-based intense moisturizing cream and its use in regular skin care routine can be beneficial, particularly for acne prone and dry skin as it improves the skin hydration levels.

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Trending Anti-Aging Peptides

Cosmetics ◽

10.3390/cosmetics7040091 ◽

2020 ◽

Vol 7 (4) ◽

pp. 91

Author(s):

Marta Salvador Ferreira ◽

Maria Catarina Magalhães ◽

José Manuel Sousa-Lobo ◽

Isabel Filipa Almeida

Keyword(s):

Synthetic Peptides ◽

Skin Care ◽

Active Ingredients ◽

Technical Data ◽

Dominant Source ◽

Scientific Databases ◽

Cosmetic Industry ◽

Cosmetic Formulations ◽

Market Trends ◽

Meaningful Data

The development of synthetic peptides for skin care dates to the 1980s. The cosmetic industry periodically launches new peptides, as they are promising and appealing active ingredients in the growing and innovative cosmetics market. In this study, trends in the use of peptides in anti-aging products were analyzed by comparing the composition of the products marketed in 2011 with products launched or reformulated in 2018. The scientific and marketing evidence for their application as active ingredients in anti-aging cosmetics was also compiled from products’ labels, suppliers’ technical data forms and online scientific databases. The use of peptides in anti-aging cosmetics increased by 7.2%, while the variety and the number of peptide combinations in products have increased by 88.5%. The most used peptides in antiaging cosmetic formulations are, in descending order, Palmitoyl Tetrapeptide-7, Palmitoyl Oligopeptide and Acetyl Hexapeptide-8. In 2011, the majority of peptides were obtained from synthesis, while in 2018, biotechnology processing was the dominant source. This study provides an overview of the market trends regarding the use of peptides in anti-aging products, providing meaningful data for scientists involved in the development of new peptides to identify opportunities for innovation in this area.

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Selection and Application of Synthetic versus Natural Emollients in the Formulation of Skin Care Products

Revista de Chimie ◽

10.37358/rc.19.8.7423 ◽

2019 ◽

Vol 70 (8) ◽

pp. 2764-2768 ◽

Cited By ~ 2

Author(s):

Anca Maria Juncan ◽

Claudiu Morgovan ◽

Luca Liviu Rus

Keyword(s):

Quality Control ◽

Helianthus Annuus ◽

Sunflower Seed ◽

Skin Care ◽

Natural Origin ◽

Synthetic Oil ◽

Cosmetic Formulations ◽

Hand Cream ◽

Skin Care Products

Two emollient ingredients with proven sensorial properties were slected for the development of a hand cream cosmetic formulations, and comparatively analysed. A synthetic oil (Polydecene) and a natural blend (Jojoba Esters and Acacia Decurrens Flower Wax and Helianthus Annuus (Sunflower) Seed Wax and Polyglycerin-3) were incorporated in cosmetic formulations for hand care. The aim of this study was to evaluate the quality control and the cosmetic qualities of the developed formulations, comparatively, of topical applied synthetic oil versus a natural origin wax blend.

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