scholarly journals Extended lipid profile in Romanian ischemic stroke patients in relation to stroke severity and outcome: a path analysis model

2019 ◽  
Author(s):  
Adina Hutanu ◽  
Mihaela Iancu ◽  
Minodora Dobreanu ◽  
Oana Oprea ◽  
Stefan Barbu ◽  
...  
Keyword(s):  
Ischemic Stroke ◽  
Path Analysis ◽  
Lipid Profile ◽  
Stroke Severity ◽  
Analysis Model ◽  
Stroke Patients ◽  
Path Analysis Model

A path analysis model for grooming performance in stroke patients

2018 ◽  
Vol 41 (24) ◽  
pp. 2958-2964 ◽  
Author(s):  
Takaaki Fujita ◽  
Atsushi Sato ◽  
Kazuaki Iokawa ◽  
Kazuhiro Yamane ◽  
Yuichi Yamamoto ◽  
...  
Keyword(s):  
Path Analysis ◽  
Analysis Model ◽  
Stroke Patients ◽  
Path Analysis Model

The Influence of Leadership on the Transfer of Knowledge and Work Effectivity at Secretariat Office in Boven Digoel Regency

2020 ◽  
Vol 2 (4) ◽  
pp. 44-52
Author(s):  
Yoseph Awunim ◽  
Abdul Rahman Kadir ◽  
Mahlia Muis
Keyword(s):  
Data Analysis ◽  
Knowledge Transfer ◽  
Path Analysis ◽  
Positive Impact ◽  
Direct Impact ◽  
Transfer Of Knowledge ◽  
Analysis Model ◽  
Work Effectiveness ◽  
Statistical Results ◽  
Path Analysis Model

The research objective is to analyze the direct impact of leadership toward transfer knowledge and work effectiveness in Boven Digoel. Data analysis in this research is quantitative using a path analysis model (path analysis) with the help of Smart PLS Software version 3.2 .8. The research distributed questionnaires to 89 respondents of officers assigned at the secretariat office in Boven Digoel Regency. On the basis of statistical results, it was found that leadership can be said to have impacted positively and significant knowledge transfer and work effectiveness. The knowledge transfer also has a positive impact on work effectiveness.

scholarly journals Influential Path of Social Risk Factors toward Suicidal Behavior—Evidence from Chinese Sina Weibo Users 2013–2018

2021 ◽  
Vol 18 (5) ◽  
pp. 2604
Author(s):  
Yujin Han ◽  
He Li ◽  
Yunyu Xiao ◽  
Ang Li ◽  
Tingshao Zhu
Keyword(s):  
Risk Factors ◽  
Path Analysis ◽  
Suicide Prevention ◽  
Suicidal Behavior ◽  
Empirical Support ◽  
National Bureau ◽  
Social Risk ◽  
Analysis Model ◽  
The Relationship ◽  
Path Analysis Model

(1) Purpose: The purpose of this study was to determine suicidal risk factors, the relationship and the underlying mechanism between social variables and suicidal behavior. We hope to provide empirical support for the future suicide prevention of social media users at the social level. (2) Methods: The path analysis model with psychache as the mediate variable was constructed to analyze the relationship between suicidal behavior and selected social macro variables. The data for our research was taken from the Chinese Suicide Dictionary, Moral Foundation Dictionary, Cultural Value Dictionary and National Bureau of Statistics. (3) Results: The path analysis model was an adequate representation of the data. With the mediator psychache, higher authority vice, individualism, and disposable income of residents significantly predicted less suicidal behavior. Purity vice, collectivism, and proportion of the primary industry had positive significant effect on suicidal behavior via the mediator psychache. The coefficients of harm vice, fairness vice, ingroup vice, public transport and car for every 10,000 people, urban population density, gross domestic product (GDP), urban registered unemployment rate, and crude divorce rate were not significant. Furthermore, we applied the model to three major economic development belts in China. The model’s result meant different economic zones had no influence on the model designed in our study. (4) Conclusions: Our evidence informs population-based suicide prevention policymakers that incorporating some social factors like authority vice, individualism, etc. can help prevent suicidal ideation in China.

Prestroke statin use enhances collateralization in acute ischemic stroke patients

2020 ◽  
Vol 38 (4) ◽  
pp. 311-321
Author(s):  
Jiaying Zhu ◽  
Mengmeng Ma ◽  
Jinghuan Fang ◽  
Jiajia Bao ◽  
Shuju Dong ◽  
...  
Keyword(s):  
Ischemic Stroke ◽  
Middle Cerebral Artery ◽  
Acute Ischemic Stroke ◽  
Statin Therapy ◽  
Cerebral Artery ◽  
Functional Outcomes ◽  
Collateral Circulation ◽  
Stroke Severity ◽  
Stroke Patients ◽  
Statin Use

Background: Statin therapy has been shown to be effective in the prevention of ischemic stroke. In addition, recent studies have suggested that prior statin therapy could lower the initial stroke severity and improve stroke functional outcomes in the event of stroke. It was speculated that prestroke statin use may enhance collateral circulation and result in favorable functional outcomes. Objective: The aim of the study was to investigate the association of prestroke statin use with leptomeningeal collaterals and to determine the association of prestroke statin use with stroke severity and functional outcome in acute ischemic stroke patients. Methods: We prospectively and consecutively enrolled 239 acute ischemic stroke patients with acute infarction due to occlusion of the middle cerebral artery within 24 h in the neurology department of West China Hospital from May 2011 to April 2017. Computed tomographic angiography (CTA) imaging was performed for all patients to detect middle cerebral artery thrombus; regional leptomeningeal collateral score (rLMCS) was used to assess the degree of collateral circulation; the National Institutes of Health Stroke Scale (NIHSS) was used to measure stroke severity at admission; the modified Rankin scale (mRS) was used to measure outcome at 90 days; and premorbid medications were recorded. Univariate and multivariate analyses were performed. Results: Overall, 239 patients met the inclusion criteria. Fifty-four patients used statins, and 185 did not use statins before stroke onset. Prestroke statin use was independently associated with good collateral circulation (rLMCS > 10) (odds ratio [OR], 4.786; 95% confidence interval [CI], 1.195–19.171; P = 0.027). Prestroke statin use was not independently associated with lower stroke severity (NIHSS score≤14) (OR, 1.955; 95% CI, 0.657–5.816; p = 0.228), but prestroke statin use was independently associated with favorable outcome (mRS score≤2) (OR, 3.868; 95% CI, 1.325–11.289; P = 0.013). Conclusions: Our findings suggest that prestroke statin use was associated with good leptomeningeal collaterals and clinical outcomes in acute ischemic stroke (AIS) patients presenting with occlusion of the middle cerebral artery. However, clinical studies should be conducted to verify this claim.

scholarly journals Association of Anemia with Stroke Severity in Acute Ischemic Stroke Patients

Cureus ◽  
2018 ◽  
Author(s):  
Muhammad F Khan ◽  
Ibrahim Shamael ◽  
Qamar Zaman ◽  
Asad Mahmood ◽  
Maimoona Siddiqui
Keyword(s):  
Ischemic Stroke ◽  
Acute Ischemic Stroke ◽  
Stroke Severity ◽  
Stroke Patients

scholarly journals CD163 as a Potential Biomarker of Monocyte Activation in Ischemic Stroke Patients

2021 ◽  
Vol 22 (13) ◽  
pp. 6712
Author(s):  
Rosaria Greco ◽  
Chiara Demartini ◽  
Anna Maria Zanaboni ◽  
Elena Tumelero ◽  
Alessandra Persico ◽  
...  
Keyword(s):  
Ischemic Stroke ◽  
Stroke Severity ◽  
Mrna Levels ◽  
Monocyte Count ◽  
Stroke Patients ◽  
Inflammatory Status ◽  
Specific Distribution ◽  
Cd163 Expression ◽  
Potential Biomarker ◽  
Complex Correlation

In ischemic stroke patients, a higher monocyte count is associated with disease severity and worse prognosis. The complex correlation between subset phenotypes and functions underscores the importance of clarifying the role of monocyte subpopulations. We examined the subtype-specific distribution of the CD163+ and CD80+ circulating monocytes and evaluated their association with the inflammatory status in 26 ischemic stroke patients and 16 healthy controls. An increased percentage of CD163+/CD16+ and CD163+/CD14++ events occurred 24 and 48 h after a stroke compared to the controls. CD163+ expression was more pronounced in CD16+ non-classical and intermediate monocytes, as compared to CD14+ classical subtype, 24 h after stroke. Conversely, the percentage of CD80+/CD16+ events was unaffected in patients; meanwhile, the percentage of CD80+/CD14+ events significantly increased only 24 h after stroke. Interleukin (IL)-1beta, TNF-alpha, and IL-4 mRNA levels were higher, while IL-10 mRNA levels were reduced in total monocytes from patients versus controls, at either 24 h or 48 h after stroke. The percentage of CD163+/CD16+ events 24 h after stroke was positively associated with NIHSS score and mRS at admission, suggesting that stroke severity and disability are relevant triggers for CD163+ expression in circulating CD16+ monocytes.

scholarly journals Predictors of the functional outcome after thrombolysis in an Egyptian patients’ sample

2021 ◽  
Vol 57 (1) ◽  
Author(s):  
H. M. Eldeeb ◽  
D. H. Elsalamawy ◽  
A. M. Elabd ◽  
H. S. Abdelraheem
Keyword(s):  
Ischemic Stroke ◽  
Hospital Stay ◽  
Functional Outcome ◽  
Arterial Occlusion ◽  
University Hospital ◽  
Stroke Severity ◽  
Stroke Patients ◽  
Predicting Factors ◽  
Egyptian Patients ◽  
Cerebrovascular Stroke

Abstract Background About 6.2 million individuals worldwide and approximately 200 Egyptians/100,000 citizens have cerebrovascular stroke annually, and only less than 1% of stroke patients received intravenous (IV) thrombolysis in 2014. Outcome of the ischemic stroke after IV thrombolysis varies, and there is lack of data about the predicting factors that contributes to the outcome of ischemic strokes after IV thrombolysis in Egypt. Objective The aim of this work is to study the predictors of the functional outcome of ischemic cerebrovascular stroke after IV thrombolysis in Egyptian patients. Patients and methods This is a prospective study that includes acute ischemic stroke patients who received IV thrombolysis at the Alexandria University Hospital during the year from February 2017 to February 2018, and they were evaluated initially by Rapid Arterial Occlusion Evaluation (RACE) scale and followed-up serially for 6 months after thrombolysis using the National Institutes of Health Stroke Scale (NIHSS) and modified ranking score (mRS). Results Forty-five patients are included; 56% had favorable functional outcome (mRS 0–2) after 6 months, 68% had ≥ 4 points improvement in NIHSS after 6 months, and 13% had hemorrhagic conversion with 18% mortality rate. High initial RACE scale and long hospital stay are associated with poor functional outcome 6 months after thrombolysis. Conclusion Stroke severity demonstrated by high initial RACE and the duration of hospital stay are the two most significant predictors with an impact on the functional outcome of ischemic cerebrovascular stroke after thrombolysis.

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